USP10 binds to and stabilizes PFKFB4, enhancing glycolytic ATP production, which activates the urea cycle and elevates fumarate. This inhibits histone demethylase KDM1A, leading to increased H3K4me1 enrichment at the Rad51 promoter and direct activation of Rad51 transcription, which confers lung cancer radioresistance. The PFKFB4 inhibitor 5MPN targets
Yunshang Chen +7 more
wiley +1 more source
Anisotropic Memristive Switching in NbOCl2 Enabled by Directional Oxygen Ion Migration
This study investigates strongly orientation‐dependent memristive switching in anisotropic NbOCl2, observed exclusively along the in‐plane c‐axis. The switching originates from direction‐selective oxygen‐ion migration and vacancy propagation that modulate the Pd/NbOCl2 Schottky barrier, enabling short‐term plasticity.
Caokun Wang +6 more
wiley +1 more source
Considerations for managing legacy phosphorus in the Western Lake Erie Basin. [PDF]
Johnson LT, Baird T, Selzer M.
europepmc +1 more source
Ti‐doped Zr/Ti bimetallic MOFs activate neighboring Zr sites to selectively capture phospholipids from serum through cooperative interactions. In nontargeted screening, the material minimizes matrix interference, expands detectable feature coverage, and enables broad recovery of diverse chemical hazards, providing a powerful cleanup strategy for LC ...
Yanmin Liang +5 more
wiley +1 more source
Soil microbial biomass in tropical coastal shelterbelts of Hainan Island: seasonal characteristics and responses to environmental factors. [PDF]
Chen H +8 more
europepmc +1 more source
Balancing Bulk Solution Chemistry and Cation Solvation for Stable Aqueous Aluminum Batteries
A dual‐scale electrolyte design balances bulk solution chemistry and cation solvation in aqueous aluminum batteries. Regulation of the bulk solution preserves high ionic conductivity and electrochemical stability, while modulation of the Al3+ solvation environment lowers desolvation penalties and suppresses hydrogen evolution. This balanced electrolyte
Bei‐Er Jia +18 more
wiley +1 more source
Patient characteristics associated with the need for high doses of tenapanor hydrochloride in dialysis patients with hyperphosphatemia: A pooled analysis of three clinical trials. [PDF]
Nagano N +4 more
europepmc +1 more source
Enhanced Ionic Conductivity at the Solid Electrolyte Interphase of Oxygen‐Doped Li6PS5Cl
Machine‐learned molecular dynamics and machine‐learning‐based phase identification reveal the kinetically formed SEI at buried Li | Li6PS5Cl interfaces. The SEI is dominated by Li2S‐based anion‐substituted phases, while oxygen doping enhances SEI ionic conductivity.
Sojeong Yang +6 more
wiley +1 more source
The Geologic Rôle of Phosphorus [PDF]
openaire +2 more sources
Ex vitro standardization enables evaluation of phosphorus-use strategies in Pampa biome grasses. [PDF]
Farias J +10 more
europepmc +1 more source

