Results 111 to 120 of about 900,190 (260)

A novel PHKA2 mutation in a Chinese child with glycogen storage disease type IXa: a case report and literature review

BMC Medical Genetics, 2019
Background PHKA2 gene mutations can cause liver phosphorylase kinase (PhK) deficiency, resulting in glycogen storage disease type IXa (GSD IXa). Elevated liver transaminase levels and liver enlargement are the most frequent phenotypes of GSD IXa. However,
Junling Fu, Tong Wang, Xinhua Xiao
doaj   +1 more source

Intersubunit communication in glycogen phosphorylase influences substrate recognition at the catalytic sites

Amino Acids
Glycogen phosphorylase (GP) is biologically active as a dimer of identical subunits, each activated by phosphorylation of the serine-14 residue. GP exists in three interconvertible forms, namely GPa (di-phosphorylated form), GPab (mono-phosphorylated ...
Nahori Kamada, Ayato Ikeda, Yasushi Makino, Hiroshi Matsubara   +3 more
doaj   +1 more source

Computational and Pharmacological Evaluation of Ferrocene-Based Acyl Ureas and Homoleptic Cadmium Carboxylate Derivatives for Anti-diabetic Potential

Frontiers in Pharmacology, 2018
We investigated possible anti-diabetic effect of ferrocene-based acyl ureas: 4-ferrocenyl aniline (PFA), 1-(4-chlorobenzoyl)-3-(4-ferrocenylphenyl) urea (DPC1), 1-(3-chlorobenzoyl)-3-(4-ferrocenylphenyl) urea (DMC1), 1-(2-chlorobenzoyl)-3-(4 ...
Shahar Bano, Arif-ullah Khan, Faiza Asghar, Faiza Asghar, Muhammad Usman, Amin Badshah, Saqib Ali   +6 more
doaj   +1 more source

Lipoproteins of Mycobacterium tuberculosis : an abundant and functionally diverse class of cell envelope components [PDF]

, 2004
Mycobacterium tuberculosis remains the predominant bacterial scourge of mankind. Understanding of its biology and pathogenicity has been greatly advanced by the determination of whole genome sequences for this organism.
Harrington, Dean, Sutcliffe, Iain
core   +1 more source

Comprehensive structural and functional analysis of hVEGFR1: Insights into phosphorylation, molecular interactions, and potential inhibitors through docking and dynamics simulations

Cancer Treatment and Research Communications
Vascular Endothelial Growth Factor Receptor 1 (VEGFR1), is an enzyme with tyrosine kinase activity that plays a pivotal role in angiogenesis, the process of new blood vessel formation.
Manne Munikumar, Jangampalli Adi Pradeepkiran, Marineni Kiran Kumar, Swathi Banapuram, Akshatha Bhat Edurkala   +4 more
doaj   +1 more source

Evidence for a Phosphorylated Form of Calmodulin in Chicken Brain and Muscle [PDF]

, 1983
Phosphocalmodulin (PCaM) was identified after analysis of calmodulin (CaM) preparations by two-dimensional gel electrophoresis by using a modified ampholyte system to resolve very acidic proteins.
Lazarides, Elias, Plancke, Yves D.
core  

The maximum activities of hexokinase, phosphorylase, phosphofructokinase, glycerol phosphate dehydrogenases, lactate dehydrogenase, octopine dehydrogenase, phosphoenolpyruvate carboxykinase, nucleoside diphosphatekinase, glutamate-oxaloacetate transaminase and arginine kinase in relation to carbohydrate utilization in muscles from marine invertebrates [PDF]

, 1976
Victor A. Zammit, E. A. Newsholme
openalex   +1 more source

Pathway-oriented action of dietary essential oils to prevent muscle protein oxidation and texture deterioration of farmed rainbow trout

Animal, 2019
Recently, great attention has been directed towards the use of essential oils from aromatic plants as antimicrobials and antioxidant in food matrix. Fish is well known to be a high perishable food. Indeed, fish muscle is susceptible to suffer protein and
H.M.C. Santos, L. Méndez, G. Secci, G. Parisi, R. Martelli, I. Medina   +5 more
doaj   +1 more source

Stimulation of rat liver phosphorylase kinase by micromolar concentrations of Ca²⁺ [PDF]

, 1975
John C. Khoo, Daniel Steinberg
openalex   +1 more source

Activation of type II calcium/calmodulin-dependent protein kinase by Ca^(2+)/calmodulin is inhibited by autophosphorylation of threonine within the calmodulin-binding domain [PDF]

, 1990
It is now well established that autophosphorylation of a threonine residue located next to each calmodulin-binding domain in the subunits of type II Ca^(2+)/calmodulin-dependent protein kinase causes the kinase to remain active, although at a reduced ...
Kennedy, Mary B., Miller, Stephen G., Patton, Bruce L.   +2 more
core