Results 11 to 20 of about 28,187 (220)

Enzymatic regulation of glycogenolysis in a subarctic population of the wood frog: implications for extreme freeze tolerance. [PDF]

open access: yesPLoS ONE, 2013
The wood frog, Rana sylvatica, from Interior Alaska survives freezing at -16°C, a temperature 10-13°C below that tolerated by its southern conspecifics. We investigated the hepatic freezing response in this northern phenotype to determine if its profound
M Clara F do Amaral   +2 more
doaj   +1 more source

Phosphorylase Kinase Inhibition Therapy in Burns and Scalds [PDF]

open access: yesBioDiscovery, 2017
Severe burns and scalds almost always result in unsightly hypertrophic scarring. Among the important processes involved in scarring are fibroblast formation and transformation of fibroblasts into myofibroblasts.
Madalene Heng
doaj   +3 more sources

Glycogenolysis Is Crucial for Astrocytic Glycogen Accumulation and Brain Damage after Reperfusion in Ischemic Stroke

open access: yesiScience, 2020
Summary: Astrocytic glycogen is an important energy reserve in the brain and is believed to supply fuel during energy crisis. However, the pattern of glycogen metabolism in ischemic stroke and its potential therapeutic impact on neurological outcomes are
Yanhui Cai   +13 more
doaj   +1 more source

Oximes: Novel Therapeutics with Anticancer and Anti-Inflammatory Potential

open access: yesBiomolecules, 2021
Oximes have been studied for decades because of their significant roles as acetylcholinesterase reactivators. Over the last twenty years, a large number of oximes have been reported with useful pharmaceutical properties, including compounds with ...
Igor A. Schepetkin   +4 more
doaj   +1 more source

A female patient with GSD IXc developing multiple and recurrent hepatocellular carcinoma: a case report and literature review

open access: yesHuman Genome Variation, 2021
Glycogen storage disease type IX (GSD IX), the most common form of GSD, is caused by a defect in phosphorylase kinase (PhK). We describe the case of a female patient with GSD IXc harboring a homozygous mutation in PHKG2 (NM_000294.3; PHKG2 (c ...
Jun Kido   +6 more
doaj   +1 more source

Generation of human induced pluripotent stem cell line, KRIBBi003-A, from urinary cells of a patient with glycogen storage disease type IXa

open access: yesStem Cell Research, 2021
Glycogen storage disease type IXa (GSD IXa) is a rare genetic disorder characterized by phosphorylase kinase (PhK) deficiency, which leads to excessive glycogen accumulation in the liver.
Yongbo Shin   +6 more
doaj   +1 more source

Regulation of yeast phosphorylase by phosphorylase kinase and cAMP‐dependent protein kinase [PDF]

open access: yesFEBS Letters, 1983
Yeast phosphorylase is phosphorylated and activated by a cyclic AMP‐independent protein kinase (called phosphorylase kinase) and a cyclic AMP‐dependent protein kinase. Only in the presence of both kinases is phosphorylase fully activated and phosphorylated.
Wingender-Drissen, Ruth   +1 more
openaire   +2 more sources

Changes in phosphorylation of chicken breast muscle in response to L-histidine introduction under low-NaCl conditions

open access: yesCyTA - Journal of Food, 2021
In an attempt to positively regulate meat quality at low NaCl concentration, the influence of L-histidine (L-his) introduction on the postmortem phosphorylation of chicken breast muscle protein that had been cured for 16 h at 1% NaCl was investigated at ...
Jiahui Li   +5 more
doaj   +1 more source

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