Results 241 to 250 of about 2,046,842 (395)

Induced Proximity Approach Enables the Recombinant Production of Polyphosphorylated Silk Proteins with Improved Adhesiveness. [PDF]

Biomacromolecules
Möttönen NB, Fan R, Aspholm-Tsironi S, Keskitalo S, Tuhkala A, Varjosalo M, Aranko AS.   +6 more
europepmc   +1 more source

Mto2 multisite phosphorylation inactivates non-spindle microtubule nucleation complexes during mitosis [PDF]

, 2015
Weronika E. Borek, Lynda Groocock, Itaru Samejima, Juan Zou, Flávia de Lima Alves, Juri Rappsilber, Kenneth E. Sawin   +6 more
openalex   +1 more source

The Diverse Neuromuscular Spectrum of VPS13A Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective VPS13A disease (chorea‐acanthocytosis) is a rare neurodegenerative disorder caused by biallelic variants in VPS13A, typically presenting with hyperkinetic movement disorders, while neuromuscular signs are often mild. The aim of the project was to investigate the frequency and severity of neuromuscular impairment in VPS13A disease ...
Anne Buchberger, Evamaria Riedel, Marie Hackenberg, Alexander Mensch, Stefanie Beck‐Woedl, Joohyun Park, Tobias B. Haack, Bernhard Haslinger, Jan Kirschke, Holger Prokisch, Andreas Hermann, Christian Mawrin, Adrian Danek, Benedikt Schoser, Kevin Peikert, Marcus Deschauer, Isabell Cordts   +16 more
wiley   +1 more source

Global phosphoproteome analysis identifies PeVYV P4-induced host protein phosphorylation changes that facilitate viral proliferation. [PDF]

BMC Plant Biol
Li S, Yang X, Zhang Y, Luo X, Zhang Z, OuYang X, Liu H, Chen Y, Xu Y, Ye X, Lei X, Zhang S, Liu Y.   +12 more
europepmc   +1 more source

Cyclin-dependent kinase 5-mediated phosphorylation of chloride intracellular channel 4 promotes oxidative stress-induced neuronal death [PDF]

, 2018
Dong Guo, Wenting Xie, Pan Xiong, Huifang Li, Siqi Wang, Guimiao Chen, Yuehong Gao, Jiechao Zhou, Ye Zhang, Guojun Bu, Maoqiang Xue, Jie Zhang   +11 more
openalex   +1 more source

Exosome Proteomics of SOD1D90A Mutation Suggest Early Disease Mechanisms, and FN1 as a Biomarker

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Amyotrophic lateral sclerosis (ALS) is a neuromuscular disease. Super oxide dismutase 1 (SOD1) gene mutations cause ALS, and the D90A mutation is associated with primarily upper motor neuron (UMN) loss. Objective Our goal is to reveal the early cellular events in ALS pathology and identify potential pharmacokinetic biomarkers, using well ...
Mukesh Gautam, Ali Laith, Aslihan Gunel, Melda Yilmaz, Nazli Basak, Halil Idrisoglu, P. Hande Ozdinler   +6 more
wiley   +1 more source

Potential phosphorylation of Liprin-α1 at threonine 701 regulates integrin-mediated cell motility. [PDF]

PLoS One
Ramella M, Brambilla D, Surini S, Tonoli D, Ribolla LM, de Curtis I.   +5 more
europepmc   +1 more source

Silencing Kinase-Interacting Stathmin Gene Enhances Erlotinib Sensitivity by Inhibiting Ser10 p27 Phosphorylation in Epidermal Growth Factor Receptor–Expressing Breast Cancer [PDF]

, 2010
Dongwei Zhang, Ana M. Tari, Uǧur Akar, Banu Arun, Tiffany A. LaFortune, René Nieves-Alicea, Gabriel N. Hortobágyi, Naoto T. Ueno   +7 more
openalex   +1 more source

Impact of APOE ε4 Genotype Load on Cognitive Function and Lipid Metabolism in Patients With Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Apolipoprotein ε4 (APOE ε4) is a potent genetic risk factor for Alzheimer's disease (AD). However, its role in cerebral small vessel disease (CSVD) remains unclear. Given the clinical and pathological similarities between CSVD and AD, this study aimed to investigate the associations of APOE ε4 gene dosage with cognitive function and
Tingru Jin, Haocheng Yang, Feng Liu, Sihao Lin, Junru Hu, Jian Wang, Yulan Gou   +6 more
wiley   +1 more source

Inhibition of TBK1/IKKε mediated RIPK1 phosphorylation sensitizes tumors to immune cell killing. [PDF]

Cell Death Discov
Piskopou A, Vredevoogd DW, Kong X, Peeper DS, Altelaar M, Stecker KE.   +5 more
europepmc   +1 more source