Results 21 to 30 of about 21,742 (223)

VH-RELATED IDIOTOPES DETECTED BY SITE-DIRECTED MUTAGENESIS [PDF]

, 1992
The function of the CD4 cell surface protein as coreceptor on T helper lymphocytes and as receptor for HIV makes this glycoprotein a prime target for an immune intervention with mAb.
Cheng, Y. H., Rieber, Ernst Peter, Riethmüller, Gert, Weiss, Elisabeth H., Weissenhorn, Winfried   +4 more
core   +1 more source

PH regulation of amphotericin B channels activity in the bilayer lipid membrane [PDF]

, 2016
Background: Amphotericin B (AmB) is a polyene antibiotic frequently applied in the treatment of systemic fungal infections in spite of its secondary effects.
Ashrafpour, M., Sepehry, H., Shahmoradi, T.   +2 more
core   +2 more sources

The Eukaryotic Elongation Factor 1 Alpha (eEF1α) from the Parasite Leishmania infantum Is Modified with the Immunomodulatory Substituent Phosphorylcholine (PC)

Molecules, 2017
Proteins and glycolipids have been found to be decorated with phosphorylcholine (PC) both in protozoa and nematodes that parasitize humans and animals. PC epitopes can provoke various effects on immune cells leading to an immunomodulation of the host’s ...
Thomas Timm, Giada Annoscia, Jochen Klein, Günter Lochnit   +3 more
doaj   +1 more source

Lubrication at physiological pressures by polyzwitterionic brushes [PDF]

, 2009
The very low sliding friction at natural synovial joints, which have friction coefficients of mu < 0.002 at pressures up to 5 megapascals or more, has to date not been attained in any human-made joints or between model surfaces in aqueous environments ...
Briscoe, Chen, Feng, Gong, Gourdon, Hills, Ishihara, J. Klein, Lee, Lis, M. Chen, Mcutchen, Moro, Nagle, Pabst, Park, Raviv, Raviv, S. P. Armes, Swann, Tadmor, W. H. Briscoe, Yaseen   +22 more
core   +1 more source

Hypoxia-degradable and long-circulating zwitterionic phosphorylcholine-based nanogel for enhanced tumor drug delivery

Acta Pharmaceutica Sinica B, 2021
Tumor microenvironment has been widely utilized for advanced drug delivery in recent years, among which hypoxia-responsive drug delivery systems have become the research hotspot. Although hypoxia-responsive micelles or polymersomes have been successfully
Shaojun Peng, Boshu Ouyang, Yongjie Xin, Wei Zhao, Shun Shen, Meixiao Zhan, Ligong Lu   +6 more
doaj   +1 more source

Does litomosoides sigmodontis synthesize dimethylethanolamine from choline? [PDF]

, 2008
Juvenile female Litomosoides sigmodontis secrete a protein (Juv-p120) highly modified with dimethylethanolamine (DMAE). In an attempt to establish the source of this decoration worms were pulsed with [3H]-choline and [3H]-ethanolamine and the radio ...
Allen, J E, Allen, Judith, Babayan, S A, Harnett, W, Houston, K M   +4 more
core   +2 more sources

Phosphorylcholine-Targeting Immunization Reduces Atherosclerosis

Journal of the American College of Cardiology, 2007
The present study evaluated the effect of phosphorylcholine (PC) immunization on the extent of experimental atherosclerosis.Immunization against oxidized lipoprotein (oxLDL) or Streptococcus pneumoconiae reduces atherosclerosis. Phosphorylcholine is the main epitope recognized by both antipneumococcus and anti-oxLDL antibodies.
Caligiuri, Giuseppina, Khallou-Laschet, Jamila, Vandaele, Marta, Gaston, Anh-Thu, Delignat, Sandrine, Mandet, Chantal, Kohler, Heinz V., Kaveri, Srini V., Nicoletti, Antonino   +8 more
openaire   +2 more sources

Hemocompatibility of β-Cyclodextrin-Modified (Methacryloyloxy)ethyl Phosphorylcholine Coated Magnetic Nanoparticles

Biomolecules, 2023
Adsorbing toxins from the blood to augment membrane-based hemodialysis is an active area of research. Films composed of β-cyclodextrin-co-(methacryloyloxy)ethyl phosphorylcholine (p(PMβCD-co-MPC)) with various monomer ratios were formed on magnetic ...
Shuhui Li, Mehdi Ghaffari Sharaf, Elyn M. Rowe, Katherine Serrano, Dana V. Devine, Larry D. Unsworth   +5 more
doaj   +1 more source

Phosphocholine-Modified Lipooligosaccharides of Haemophilus influenzae Inhibit ATP-Induced IL-1beta Release by Pulmonary Epithelial Cells [PDF]

, 2018
Phosphocholine-modified bacterial cell wall components are virulence factors enabling immune evasion and permanent colonization of the mammalian host, by mechanisms that are poorly understood.
Grau, Veronika, Koch, Christian, Magel, Ilona, McIntosh, J. Michael, Padberg, Winfried, Perniss, Alexander, Richter, Katrin, Sander, Michael, Schweda, Elke K. H., Wichmann, Sven, Wilker, Sigrid, Wolf, Philipp M.   +11 more
core   +1 more source

High fat diet deviates PtC-specific B1 B cell phagocytosis in obese mice [PDF]

, 2014
Phagocytosis had been attributed predominantly to "professional" phagocytes such as macrophages, which play critical roles in adipose tissue inflammation.
Allaimo, Danielle, Chiu, Joanna, Gong, Yuefei, Mao, Changchuin, Ow, Hooisweng, Porter, Tyrone, Vo, Hung, Wang, Yaqi, Zhong, Xuemei   +8 more
core   +1 more source