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Quorum sensing regulation by the nitrogen phosphotransferase system in Pseudomonas aeruginosa [PDF]

open access: yesJournal of Bacteriology
In the opportunistic pathogen Pseudomonas aeruginosa, the nitrogen-related phosphotransferase system (PTSNtr) influences multiple virulence behaviors. The PTSNtr is comprised of three enzymes: first PtsP, then the PtsO phosphocarrier, and the final PtsN ...
Samalee Banerjee   +6 more
doaj   +2 more sources

Characterization of the Phosphotransferase from Bacillus subtilis 1101 That Is Responsible for the Biotransformation of Zearalenone [PDF]

open access: yesToxins
Bacillus microorganisms play an important role in the zearalenone (ZEA) biotransformation process in natural environments. The phosphotransferase pathway in Bacillus is both widespread and relatively well conserved.
Yuzhuo Wu   +8 more
doaj   +2 more sources

Genomic and functional characterization of the L‑sorbose phosphotransferase system in high-risk Escherichia coli lineages [PDF]

open access: yesmSystems
Certain Escherichia coli strains belong to international high-risk clonal lineages exhibiting a combination of multidrug resistance, enhanced fitness, and increased virulence, posing major public health challenges. Investigation of characteristics beyond
Lena-Sophie Swiatek   +10 more
doaj   +2 more sources

The potential regulatory role of mannose phosphotransferase system EII in alkaline resistance of Enterococcus faecalis

open access: goldJournal of Oral Microbiology
Objective To investigate the role of mannose phosphotransferase system (Man-PTS) EII in the alkaline resistance of Enterococcus faecalis (E. faecalis).Methods The Man-PTS EIID (mptD) deletion (ΔmptD) and overexpressing (+mptD) strains of E. faecalis were
Runze Liu   +5 more
doaj   +2 more sources

A Transcriptional Analysis Showing the Effects of GH12 Combined with Fluoride for Suppressing the Acidogenicity of Streptococcus mutans Biofilms

open access: yesMicroorganisms, 2023
The acidogenicity of Streptococcus mutans is important for caries development. The antimicrobial peptide GH12 can affect the integrity of cellular membranes and the virulence factors of S. mutans.
Yuhao Zeng   +5 more
doaj   +1 more source

Mutational Analysis of N-Ethyl-N-Nitrosourea (ENU) in the Fission Yeast Schizosaccharomyces pombe

open access: yesG3: Genes, Genomes, Genetics, 2020
Forward genetics in model organisms has boosted our knowledge of the genetic bases of development, aging, and human diseases. In this experimental pipeline, it is crucial to start by inducing a large number of random mutations in the genome of the model ...
Rafael Hoyos-Manchado   +4 more
doaj   +1 more source

Naturally forming benzoic acid orientates perilipin to facilitate glyceride-type polyunsaturated fatty acid degradation via fermentation behavior

open access: yesJournal of Dairy Science, 2023
: Naturally forming benzoic acid in fermented dairy products accumulates in organisms and biomagnifies through collateral transport. The association between benzoic acid agglomeration and susceptible lipid nutrients remains obscure.
Wei Jia, Xixuan Wu, Lin Shi
doaj   +1 more source

Differential contributions of choline phosphotransferases CPT1 and CEPT1 to the biosynthesis of choline phospholipids

open access: yesJournal of Lipid Research, 2021
Choline phospholipids (PLs) such as phosphatidylcholine (PC) and 1-alkyl-2-acyl-sn-glycerophosphocholine are important components for cell membranes and also serve as a source of several lipid mediators.
Yasuhiro Horibata, Hiroyuki Sugimoto
doaj   +1 more source

RRE-deleting self-inactivating and self-activating HIV-1 vectors for improved safety [PDF]

open access: yesPeerJ, 2013
Retroviruses have been shown to efficiently delete sequences between repeats as a consequence of the template switching ability of the viral reverse transcriptase.
Narasimhachar Srinivasakumar
doaj   +2 more sources

Identification and characterization of a novel chromosomal aminoglycoside 3’-O-phosphotransferase, APH(3′)-Id, from Kluyvera intermedia DW18 isolated from the sewage of an animal farm

open access: yesFrontiers in Microbiology, 2023
BackgroundAminoglycosides, as important clinical antimicrobials, are used as second-line drugs for treating multidrug-resistant tuberculosis or combined with β-lactam drugs for treating severe infections such as sepsis.
Yuning Sha   +17 more
doaj   +1 more source

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