Results 21 to 30 of about 68,387 (225)

Diversity analysis of streptomycetes and associated phosphotranspherase genes in soil. [PDF]

open access: yesPLoS ONE, 2012
An attempt was made to verify the observation that Streptomyces griseus was prevalent in soil based on isolation work. A genus-specific PCR was developed for Streptomyces based on the housekeeping gene atpD and used to investigate species diversity ...
Paris Laskaris   +2 more
doaj   +1 more source

Engineering of GlcNAc-1-Phosphotransferase for Production of Highly Phosphorylated Lysosomal Enzymes for Enzyme Replacement Therapy

open access: yesMolecular Therapy: Methods & Clinical Development, 2017
Several lysosomal enzymes currently used for enzyme replacement therapy in patients with lysosomal storage diseases contain very low levels of mannose 6-phosphate, limiting their uptake via mannose 6-phosphate receptors on the surface of the deficient ...
Lin Liu   +3 more
doaj   +1 more source

The Phosphohistidine Phosphatase SixA Targets a Phosphotransferase System

open access: yesmBio, 2018
SixA, a well-conserved protein found in proteobacteria, actinobacteria, and cyanobacteria, is the only reported example of a bacterial phosphohistidine phosphatase. A single protein target of SixA has been reported to date: the Escherichia coli histidine
Jane E. Schulte, Mark Goulian
doaj   +1 more source

Sugar Influx Sensing by the Phosphotransferase System of Escherichia coli. [PDF]

open access: yesPLoS Biology, 2016
The phosphotransferase system (PTS) plays a pivotal role in the uptake of multiple sugars in Escherichia coli and many other bacteria. In the cell, individual sugar-specific PTS branches are interconnected through a series of phosphotransfer reactions ...
Rahul Somavanshi   +2 more
doaj   +1 more source

Aminoglycoside 3'-phosphotransferase III, a new phosphotransferase. Resistance mechanism.

open access: yesThe Journal of Antibiotics, 1975
The aminoglycoside phosphotransferase of Pseudomonas aeruginosa 21-75 was purified by affinity chromatography using dibekacin-Sephadex 4B or lividomycin A-Sepharose 4B followed by DEAE Sephadex A-50 chromatography. It had activities of both the known aminoglycoside 3'-phosphotransferases I and II, and transferred phosphate from ATP to the 3'-hydroxyl ...
YOJI UMEZAWA   +6 more
openaire   +3 more sources

Structural basis for catalysis of human choline/ethanolamine phosphotransferase 1

open access: yesNature Communications, 2023
Phosphatidylcholine (PC) and phosphatidylethanolamine (PE) are two primary components of the eukaryotic membrane and play essential roles in the maintenance of membrane integrity, lipid droplet biogenesis, autophagosome formation, and lipoprotein ...
Zhenhua Wang   +4 more
doaj   +1 more source

Whole-Cell Display of Phosphotransferase in Escherichia coli for High-Efficiency Extracellular ATP Production

open access: yesBiomolecules, 2022
Adenosine triphosphate (ATP), as a universal energy currency, takes a central role in many biochemical reactions with potential for the synthesis of numerous high-value products.
Shuai Zhao   +6 more
doaj   +1 more source

Phosphoenolpyruvate phosphotransferase system components positively regulate Klebsiella biofilm formation

open access: yesJournal of Microbiology, Immunology and Infection, 2018
Background/Purpose: Klebsiella pneumoniae is one of the leading causes of device-related infections (DRIs), which are associated with attachment of bacteria to these devices to form a biofilm.
Yu-Tze Horng   +5 more
doaj   +1 more source

NIR Light‐Driven Photocatalytic Antibacterial Hydrogels for Synergistic MRSA Biofilm Eradication and Wound Regeneration

open access: yesAdvanced Science, EarlyView.
The nanohybrid hydrogel (Fe‐BOS@C/H Gel) is composed of Fe‐Bi2O2‐XS (Fe‐BOS) photocatalysts and CS‐ADH/OHA (C/H) hydrogel. Fe‐BOS photocatalysts achieve near‐infrared (NIR) light‐driven antibacterial photocatalytic/mild photothermal therapy (APCT/MPTT), effectively eliminating methicillin‐resistant Staphylococcus aureus (MRSA) biofilms. The degradation
Dong Mo   +13 more
wiley   +1 more source

Enzyme I facilitates reverse flux from pyruvate to phosphoenolpyruvate in Escherichia coli

open access: yesNature Communications, 2017
Enzyme I, a component of the phosphoenolpyruvate-carbohydrate phosphotransferase system (PTS), converts phosphoenolpyruvate to pyruvate. Here, the authors show that Enzyme I facilitates also the reverse reaction during both gluconeogenic and glycolytic ...
Christopher P. Long   +4 more
doaj   +1 more source

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