Results 71 to 80 of about 68,387 (225)
Conformational dynamics in insulin receptor kinase reveal a type III allosteric pocket
Abstract Allosteric modulation is a promising strategy for selective kinase inhibition, yet structural insights into allosteric pockets remain limited across the human kinome. In this work, we present comprehensive characterization of a type III allosteric pocket in the insulin receptor kinase (IRK), integrating structural, conformational, and ...
Jyoti Verma, Harish Vashisth
wiley +1 more source
Abstract Members of Bacillus cereus have been documented as important bacterial pathogens in aquaculture. However, scarce information is available on B. cereus isolates as causal pathogens of big‐belly seahorses Hippocampus abdominalis. In the present study, a B. cereus isolate (SH1), recovered from a disease outbreak on a seahorse farm, was identified
Chunlei Gai +7 more
wiley +1 more source
In this study, the isolated guinea pig heart was pulse-labeled with a precursor of ethanolamine glycerophospholipid, and then chased with the non-radioactive compound for 0-8 h.
F Y Xu, K O, P C Choy
doaj +1 more source
Yeast Phosphoramidate-Adenosine Diphosphate Phosphotransferase
Abstract An enzyme, phosphoramidate-ADP phosphotransferase, has been isolated from dried bakers' yeast. We have previously shown that phosphoramide, N-phosphorylglycine, and N-phosphohistidine can act as phosphate donors. Phosphoiodohistidine was shown also to function as a phosphate donor and the enzyme was stereospecific for the l form of this ...
M J, Dowler, H I, Nakada
openaire +2 more sources
Phospholipid Interconversion and Transport Are Altered in Glaucoma
Decreased phosphatidylserine (PS) and increased phosphatidylethanolamine (PE) occur in both trabecular meshwork (TM) cells and aqueous humor due to aberrant phosphatidylserine decarboxylase (PSD) over‐expression, and variation in levels of individual PS or PE species differing by only a few acyl chains occurs due to impaired lipid transport due to ...
Genea Edwards +5 more
wiley +1 more source
Women with overweight or obesity follow intended isocaloric early and late time‐restricted eating (TRE) in a crossover trial. Shotgun plasma lipidomics reveals no significant differences between interventions, but identify pronounced lipid changes—including reductions in ceramides and phosphatidylcholines—within the early TRE.
Kristof Szekely +15 more
wiley +1 more source
Streptomyces griseus Streptomycin Phosphotransferase: Expression of Its Gene in Escherichia coli and Sequence Homology with Other Antibiotic Phosphotransferases and with Eukaryotic Protein Kinases [PDF]
Chang‐Kweng Lim +4 more
openalex +1 more source
Preliminary genetic barcodes for ash (Fraxinus) species and generation of new wide hybrids
Societal Impact Statement The world‐wide diversity of ash trees includes genetic information encoding resistance to the ash dieback fungus and the emerald ash borer beetle, which are currently devastating ash populations in Europe and North America. In order to mobilise this genetic diversity in conventional breeding programmes, we need to be able to ...
William J. Plumb +11 more
wiley +1 more source
Transient expression of uidA gene in grapevine protoplasts after PEG-mediated transformation
Leaf protoplasts, isolated from Vitis vinifera «Sakasly» and «Muscat d’Alexandrie» and protoplasts from embryogenic tissue of Vitis sp. «Seyval blanc» were incubated in the presence of PEG in a transformation solution containing the plasmid pBI426 which ...
Rahma Jardak +3 more
doaj +1 more source
Adenylate cyclase is required for chemotaxis to phosphotransferase system sugars by Escherichia coli [PDF]
Roy A. Black, A C Hobson, Julius Adler
openalex +1 more source

