Results 71 to 80 of about 68,387 (225)

Conformational dynamics in insulin receptor kinase reveal a type III allosteric pocket

open access: yesProtein Science, Volume 35, Issue 2, February 2026.
Abstract Allosteric modulation is a promising strategy for selective kinase inhibition, yet structural insights into allosteric pockets remain limited across the human kinome. In this work, we present comprehensive characterization of a type III allosteric pocket in the insulin receptor kinase (IRK), integrating structural, conformational, and ...
Jyoti Verma, Harish Vashisth
wiley   +1 more source

Isolation, identification, and pathogenic potential of Bacillus cereus from diseased big‐belly seahorse Hippocampus abdominalis

open access: yesJournal of the World Aquaculture Society, Volume 57, Issue 1, February 2026.
Abstract Members of Bacillus cereus have been documented as important bacterial pathogens in aquaculture. However, scarce information is available on B. cereus isolates as causal pathogens of big‐belly seahorses Hippocampus abdominalis. In the present study, a B. cereus isolate (SH1), recovered from a disease outbreak on a seahorse farm, was identified
Chunlei Gai   +7 more
wiley   +1 more source

Biosynthesis of plasmenylethanolamine (1-O-alk-1'-enyl-2-acyl-sn-glycero-3-phosphoethanolamine) in the guinea pig heart

open access: yesJournal of Lipid Research, 1997
In this study, the isolated guinea pig heart was pulse-labeled with a precursor of ethanolamine glycerophospholipid, and then chased with the non-radioactive compound for 0-8 h.
F Y Xu, K O, P C Choy
doaj   +1 more source

Yeast Phosphoramidate-Adenosine Diphosphate Phosphotransferase

open access: yesJournal of Biological Chemistry, 1968
Abstract An enzyme, phosphoramidate-ADP phosphotransferase, has been isolated from dried bakers' yeast. We have previously shown that phosphoramide, N-phosphorylglycine, and N-phosphohistidine can act as phosphate donors. Phosphoiodohistidine was shown also to function as a phosphate donor and the enzyme was stereospecific for the l form of this ...
M J, Dowler, H I, Nakada
openaire   +2 more sources

Phospholipid Interconversion and Transport Are Altered in Glaucoma

open access: yesThe FASEB Journal, Volume 40, Issue 2, 31 January 2026.
Decreased phosphatidylserine (PS) and increased phosphatidylethanolamine (PE) occur in both trabecular meshwork (TM) cells and aqueous humor due to aberrant phosphatidylserine decarboxylase (PSD) over‐expression, and variation in levels of individual PS or PE species differing by only a few acyl chains occurs due to impaired lipid transport due to ...
Genea Edwards   +5 more
wiley   +1 more source

Impact of Intended Isocaloric Early versus Late Time‐Restricted Eating on Plasma Lipidome in Women with Overweight or Obesity: Secondary Analysis of the ChronoFast Trial

open access: yesAdvanced Science, Volume 13, Issue 4, 19 January 2026.
Women with overweight or obesity follow intended isocaloric early and late time‐restricted eating (TRE) in a crossover trial. Shotgun plasma lipidomics reveals no significant differences between interventions, but identify pronounced lipid changes—including reductions in ceramides and phosphatidylcholines—within the early TRE.
Kristof Szekely   +15 more
wiley   +1 more source

Preliminary genetic barcodes for ash (Fraxinus) species and generation of new wide hybrids

open access: yesPLANTS, PEOPLE, PLANET, Volume 8, Issue 1, Page 245-258, January 2026.
Societal Impact Statement The world‐wide diversity of ash trees includes genetic information encoding resistance to the ash dieback fungus and the emerald ash borer beetle, which are currently devastating ash populations in Europe and North America. In order to mobilise this genetic diversity in conventional breeding programmes, we need to be able to ...
William J. Plumb   +11 more
wiley   +1 more source

Transient expression of uidA gene in grapevine protoplasts after PEG-mediated transformation

open access: yesOENO One, 2002
Leaf protoplasts, isolated from Vitis vinifera «Sakasly» and «Muscat d’Alexandrie» and protoplasts from embryogenic tissue of Vitis sp. «Seyval blanc» were incubated in the presence of PEG in a transformation solution containing the plasmid pBI426 which ...
Rahma Jardak   +3 more
doaj   +1 more source

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