Results 1 to 10 of about 8,386 (150)

Mapping the effect of configuration and protecting group pattern on glycosyl acceptor reactivity

Chemical Science, 2023
The reactivity of the acceptor alcohol can have a tremendous influence on the outcome of a glycosylation reaction, both in terms of yield and stereoselectivity.
J. V. van Hengst, Rik Hellemons, Wouter A. Remmerswaal, Koen N A van de Vrande, Thomas Hansen, Stefan van der Vorm, H. Overkleeft, G. A. van der Marel, J. Codée   +8 more
semanticscholar   +1 more source

Inductive Effects on Intramolecular Hydrogen Bond Strength: An Investigation of the Effect of an Electron-Withdrawing CF3 Group Adjacent to an Alcohol Hydrogen Bond Donor

Journal of Physical Chemistry A, 2023
This combined experimental and theoretical study seeks to determine the role that inductive effects have on hydrogen bonds by an investigation into the change in intramolecular hydrogen bond strength in 2-amino-1-trifluoromethylethanol (2ATFME) relative ...
Kaili Yap, K. D. Krantzman, R. Lavrich
semanticscholar   +1 more source

Advances in DNA, histone, and RNA methylation mechanisms in the pathophysiology of alcohol use disorder

Advances in Drug and Alcohol Research, 2023
Alcohol use disorder (AUD) has a complex, multifactorial etiology involving dysregulation across several brain regions and peripheral organs. Acute and chronic alcohol consumption cause epigenetic modifications in these systems, which underlie changes in
Tara M. Cruise, K. Kotlo, Emir Malovic, S. Pandey   +3 more
semanticscholar   +1 more source

Acceptance of Illness and Coping with Stress among Patients Undergoing Alcohol Addiction Therapy

Journal of Clinical Medicine, 2023
(1) Background: Acceptance of illness is a process in which a person with an illness accepts its presence and treats it as an integral part of their life.
Mateusz Curyło, Marlena Rynkiewicz-Andryśkiewicz, Przemysław Andryśkiewicz, M. Mikoś, Dariusz Lusina, J. W. Raczkowski, Olga Partyka, Monika Pajewska, Katarzyna Sygit, Marian Sygit, E. Cipora, M. Kaczmarski, Łukasz Gawiński, Tomasz Banaś, Łukasz Strzępek, Grzegorz Juszczyk, E. Krzych-Fałta, Ewa Bandurska, W. Ciećko, M. Zabojszcz, K. Zdziarski, A. Knyszyńska, D. Kosior, M. Marczak, A. Czerw, Remigiusz Kozłowski   +25 more
semanticscholar   +1 more source

Pantothenate Kinase Associated Neurodegeneration in Two Brothers

Acta Médica Portuguesa, 2015
Keywords: Neurodegenerative Diseases; Phosphotransferases (Alcohol Group Acceptor); Siblings.
Bruno Niemeyer de Freitas Ribeiro, Tiago Medina Salata, Lívia de Oliveira Antunes, Beatriz Salata Antunes   +3 more
doaj   +1 more source

Identifcation of small molecule enzyme inhibitors as broad-spectrum anthelmintics [PDF]

, 2019
Targeting chokepoint enzymes in metabolic pathways has led to new drugs for cancers, autoimmune disorders and infectious diseases. This is also a cornerstone approach for discovery and development of anthelmintics against nematode and flatworm parasites.
Aroian, Raffi V., Brindley, Paul J., Bulman, Christina A., Elfawal, Mostafa A., Helander, Jon, Janetka, James W., Mitreva, Makedonka, Rosa, Bruce A., Sakanari, Judy, Tyagi, Rahul, Wildman, Scott A.   +10 more
core   +3 more sources

Relating the metatranscriptome and metagenome of the human gut [PDF]

, 2014
Although the composition of the human microbiome is now wellstudied, the microbiota’s \u3e8 million genes and their regulation remain largely uncharacterized.
Boylan, Matthew R., Chan, Andrew T., Ciulla, Dawn, Earl, Ashlee M., Franzosa, Eric A., Garrett, Wendy S., Gevers, Dirk, Giannoukos, Georgia, Huttenhower, Curtis, Izard, Jacques, Morgan, Xochitl C., Reyes, Joshua, Segata, Nicola, Waldron, Levi   +13 more
core   +2 more sources

The genome of Pelobacter carbinolicus reveals surprising metabolic capabilities and physiological features [PDF]

, 2012
Background The bacterium Pelobacter carbinolicus is able to grow by fermentation, syntrophic hydrogen/formate transfer, or electron transfer to sulfur from short-chain alcohols, hydrogen or formate; it does not oxidize acetate and is not known to ferment
Cliff S Han, Derek R Lovley, Miriam L Land, Muktak Aklujkar, Olga Chertkov, Peter Brown, Raymond DiDonato, Shelley A Haveman   +7 more
core   +2 more sources

Holding your liquor: Comparison of alcohol-induced psychomotor impairment in drinkers with and without alcohol use disorder.

Alcohol, 2023
BACKGROUND Behavioral tolerance to alcohol underscores the widely accepted notion that individuals who regularly drink alcohol become less sensitive to its impairing effects.
Nathan A Didier, Ashley Vena, Abigayle R Feather, J. Grant, A. King   +4 more
semanticscholar   +1 more source

Sulfur hydrogen bonding and internal dynamics in the monohydrates of thenyl mercaptan and thenyl alcohol.

Physical Chemistry, Chemical Physics - PCCP, 2020
The monohydrates of thenyl alcohol and thenyl mercaptan have been probed in a supersonic jet expansion using chirped-pulse and Fabry-Perot Fourier-transform microwave spectroscopy.
M. Juanes, R. Saragi, R. Pinacho, J. E. Rubio, A. Lesarri   +4 more
semanticscholar   +1 more source