Results 11 to 20 of about 7,848 (188)

Relating the metatranscriptome and metagenome of the human gut [PDF]

, 2014
Although the composition of the human microbiome is now wellstudied, the microbiota’s \u3e8 million genes and their regulation remain largely uncharacterized.
Boylan, Matthew R., Chan, Andrew T., Ciulla, Dawn, Earl, Ashlee M., Franzosa, Eric A., Garrett, Wendy S., Gevers, Dirk, Giannoukos, Georgia, Huttenhower, Curtis, Izard, Jacques, Morgan, Xochitl C., Reyes, Joshua, Segata, Nicola, Waldron, Levi   +13 more
core   +2 more sources

Identifcation of small molecule enzyme inhibitors as broad-spectrum anthelmintics [PDF]

, 2019
Targeting chokepoint enzymes in metabolic pathways has led to new drugs for cancers, autoimmune disorders and infectious diseases. This is also a cornerstone approach for discovery and development of anthelmintics against nematode and flatworm parasites.
Aroian, Raffi V., Brindley, Paul J., Bulman, Christina A., Elfawal, Mostafa A., Helander, Jon, Janetka, James W., Mitreva, Makedonka, Rosa, Bruce A., Sakanari, Judy, Tyagi, Rahul, Wildman, Scott A.   +10 more
core   +2 more sources

The genome of Pelobacter carbinolicus reveals surprising metabolic capabilities and physiological features [PDF]

, 2012
Background The bacterium Pelobacter carbinolicus is able to grow by fermentation, syntrophic hydrogen/formate transfer, or electron transfer to sulfur from short-chain alcohols, hydrogen or formate; it does not oxidize acetate and is not known to ferment
Cliff S Han, Derek R Lovley, Miriam L Land, Muktak Aklujkar, Olga Chertkov, Peter Brown, Raymond DiDonato, Shelley A Haveman   +7 more
core   +2 more sources

Molecular mechanism of dietary phospholipid requirement of Atlantic salmon, Salmo salar, fry [PDF]

, 2015
The phospholipid (PL) requirement in fish is revealed by enhanced performance when larvae are provided PL-enriched diets. To elucidate the molecular mechanism underlying PL requirement in Atlantic salmon, Salmo salar, were fed a minimal PL diet and ...
Carmona-Antoñanzas, Greta, Martinez-Rubio, Laura, Taylor, John, Tocher, Douglas R   +3 more
core   +1 more source

Structural and functional insights into Mimivirus ORFans [PDF]

, 2007
Background Mimivirus isolated from A. polyphaga is the largest virus discovered so far. It is unique among all the viruses in having genes related to translation, DNA repair and replication which bear close homology to eukaryotic genes.
Fischer, Daniel, Saini, Harpreet Kaur
core   +3 more sources

Genetic methods for Rapid Detection of Medically Important Nosocomial Bactera [PDF]

, 1995
The role of the microbiology laboratory is (1) to provide infection control information, so that highly transmissible isolates may be identified and appropriate control measures instigated as rapidly as possible and (2) to provide adequate information to
Bakker-Niezen, S.H., Bartels, R.H.M.A., Rotteveel, J.J., Thijssen, H.O.M.   +3 more
core   +3 more sources

Combinatorial omics analysis reveals perturbed lysosomal homeostasis in collagen VII-deficient keratinocytes [PDF]

, 2018
The extracellular matrix protein collagen VII is part of the microenvironment of stratified epithelia and critical in organismal homeostasis. Mutations in the encoding gene COL7A1 lead to the skin disorder dystrophic epidermolysis bullosa (DEB), are ...
Athanasiou, Ioannis, Backofen, Rolf, Bornert, Olivier, Bruckner-Tuderman, Leena, Dengjel, Jörn, Erxleben, Anika, Grüning, Björn Andreas, Has, Cristina, Kiritsi, Dimitra, Leppert, Juna, Nyström, Alexander, Reinheckel, Thomas, Thriene, Kerstin, Weber, Ekkehard   +13 more
core   +1 more source

Analysis on topological alterations of functional brain networks after acute alcohol intake using resting-state functional magnetic resonance imaging and graph theory

Frontiers in Human Neuroscience, 2022
Aims Alcohol consumption could lead to a series of health problems and social issues. In the current study, we investigated the resting-state functional brain networks of healthy volunteers before and after drinking through graph-theory analysis, aiming ...
Gengbiao Zhang, Hongkun Liu, Hongyi Zheng, Ni Li, L. Kong, W. Zheng   +5 more
semanticscholar   +1 more source

Radiation Synthesis of Edible Coating Films of Nanocurcumin Based on Carboxymethyl Chitosan/Polyvinyl Alcohol to Extend the Shelf Life of Sweet Orange "Valencia"

Journal of Polymers and the Environment, 2023
Edible coating CMCS/PVA/Cur and films were prepared using γ-irradiation to extend the shelf-life of sweet orange "Valencia" fruits. Water-soluble CMCS was synthesized by carboxymethylation of chitosan.
A. Elbarbary, Ehab E. Khozemy, Asmaa Ezz El-Dein, N. El-Sawy   +3 more
semanticscholar   +1 more source

The return of metabolism: biochemistry and physiology of glycolysis

Biological Reviews, EarlyView.
ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Nana‐Maria Grüning, Federica Agostini, Camila Caldana, Johannes Hartl, Matthias Heinemann, Markus A. Keller, Jan Lukas Krüsemann, Costanza Lamperti, Carole L. Linster, Steffen N. Lindner, Julia Muenzner, Jens Nielsen, Zoran Nikoloski, Bettina Siebers, Jacky L. Snoep, Hezi Tenenboim, Bas Teusink, Spencer J. Williams, Mirjam M. C. Wamelink, Markus Ralser   +19 more
wiley   +1 more source