Results 41 to 50 of about 7,465 (118)

Metagenomic Exploration Uncovers Several Novel ‘Candidatus’ Species Involved in Acetate Metabolism in High‐Ammonia Thermophilic Biogas Processes

open access: yesMicrobial Biotechnology, Volume 18, Issue 3, March 2025.
Metagenomic analysis of three thermophilic species was performed to identify key species for stable biogas production at high free ammonia levels (> 0.7 g/L). Potential acetogens and syntrophic acetate‐oxidising bacteria (SAOB) were recovered by looking for genes of the Wood–Ljungdahl pathway and glycine synthase reductase pathway.
George B. Cheng   +2 more
wiley   +1 more source

The Mysterious World of Non‐Canonical Caps – What We Know and Why We Need New Sequencing Techniques

open access: yesChemBioChem, Volume 26, Issue 3, February 1, 2025.
This review describes sophisticated methodologies such as LC–MS that enabled the identification of 5’ non‐canonical RNA caps and also surveys so far developed sequencing methods, evaluating their advantages and disadvantages. It emphasizes the need for developing new, reliable sequencing techniques to identify RNA types with non‐canonical caps enabling
Flaminia Mancini, Hana Cahova
wiley   +1 more source

Paradigms of convergent evolution in enzymes

open access: yesThe FEBS Journal, Volume 292, Issue 3, Page 537-555, February 2025.
Some enzymes are able to catalyse the same reaction despite possessing different structures. Here, we used a combined strategy of analysing published literature and knowledge‐based computational resources to explore this. We conclude that multiple varieties of convergent functional evolution exist to date, but that it is necessary to investigate ...
Ioannis G. Riziotis   +5 more
wiley   +1 more source

The C3H gene PtZFP2‐like in Pinellia ternata acts as a positive regulator of the resistance to soft rot caused by Pectobacterium carotovorum

open access: yesPhysiologia Plantarum, Volume 177, Issue 1, January/February 2025.
Abstract Pinellia ternata (Thunb.) Breit is a member of the Araceae family and is globally distributed. The dry tuber has been used as a traditional Chinese medicine for over 2,000 years. With agricultural development, the harm of soft rot to P. ternata is an increasing problem.
Ming Luo   +4 more
wiley   +1 more source

Azulene-Based Donor-Acceptor Systems: Synthesis, Optical, and Electrochemical Properties.

open access: yesChemistry, 2017
We describe the synthesis and properties of azulene-substituted 1,1,4,4-tetracyanobutadienes (AzTCBDs) and heteroazulenyl TCBDs. TCBD derivatives were prepared in good to excellent yields through reaction of the corresponding 1-ethynylazulenes with ...
Taku Shoji, S. Ito
semanticscholar   +1 more source

Revealing the Mechanisms of Shikonin Against Diabetic Wounds: A Combined Network Pharmacology and In Vitro Investigation

open access: yesJournal of Diabetes Research, Volume 2025, Issue 1, 2025.
Background: Shikonin (SHK) possesses extensive pharmacological effects including antimicrobial and anti‐inflammatory properties for diabetic wound (DW), while its molecular mechanism remains to be clarified. In this study, we investigated the potential mechanisms of SHK in treating DW by combining network pharmacology and in vitro experiments. Methods:
Meng Tian   +9 more
wiley   +1 more source

The One Health approach in food safety: Challenges and opportunities

open access: yesFood Frontiers, Volume 5, Issue 5, Page 1837-1865, September 2024.
Abstract According to the World Health Organization, contaminated food causes approximately 600 million cases of illness and 420,000 associated deaths worldwide each year. In this scenario, food safety is a crucial task, which is based in the application of correct hygiene practices throughout the entire food production chain: from farm to table ...
Cristina Rodríguez‐Melcón   +2 more
wiley   +1 more source

Strategies for Detecting Aminoacylation and Aminoacyl‐tRNA Editing in vitro and in Cells

open access: yesIsrael Journal of Chemistry, Volume 64, Issue 8-9, September 2024.
Abstract Aminoacyl‐tRNA synthetases (aaRSs) maintain translational fidelity by ensuring the formation of correct aminoacyl‐tRNA pairs. Numerous point mutations in human aaRSs have been linked to disease phenotypes. Structural studies of aaRSs from human pathogens encoding unique domains support these enzymes as potential candidates for therapeutics ...
Rylan R. Watkins   +2 more
wiley   +1 more source

Alcohol Consumption Habits Among Young Adults: Perceptions of Personal Alcohol Consumption in Comparison to the Peer Group’s

open access: yes, 2016
In the United States, binge drinking is considered a ‘normal’ experience among teens and young adults; however, excessive alcohol consumption often results in severe or even fatal consequences.
A. Carlin   +4 more
semanticscholar   +1 more source

Inflammatory Microenvironment‐Responsive Hydrogels Enclosed with Quorum Sensing Inhibitor for Treating Post‐Traumatic Osteomyelitis

open access: yesAdvanced Science, Volume 11, Issue 20, May 28, 2024.
Inflammatory microenvironment targeted hydrogel promotes osteogenesis and inhibits inflammation in post‐traumatic osteomyelitis by responding to severe oxidative stress or acid abscess environment, and subsequently releasing quorum sensing inhibitors. It can inhibit “bacteria‐to‐bacteria communication” to clear planktonic bacteria and biofilms, reduce ...
Wenting Zhang   +8 more
wiley   +1 more source

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