Results 71 to 80 of about 7,386,477 (299)

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Identification of Two Common Bottlenose Dolphin (Tursiops truncatus) Ecotypes in the Guadeloupe Archipelago, Eastern Caribbean

Animals
The common bottlenose dolphin (Tursiops truncatus) exhibits significant intraspecific diversity globally, with distinct ecotypes identified in various regions.
Rachel Haderlé, Laurent Bouveret, Bruno Serranito, Paula Méndez-Fernandez, Olivier Adam, Mélodie Penel, Jérôme Couvat, Iwan Le Berre, Jean-Luc Jung   +8 more
doaj   +1 more source

Revisiting giraffe photo-identification using deep learning and network analysis

bioRxiv, 2020
An increasing number of research programs rely on photographic capture-recapture (vs. direct marking) of individuals to study distribution and demography within animal populations.
V. Miele, Gaspard Dussert, B. Spataro, S. Chamaillé‐Jammes, D. Allainé, C. Bonenfant   +5 more
semanticscholar   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Performance of visual vs. software-assisted photo-identification in mark-recapture studies: a case study examining different life stages of the Pacific Horned Frog (Ceratophrys stolzmanni)

, 2020
The use of individual phenotypic features as non-invasive marks through photo-identification (photo-ID) has many advantages for individual-based field studies.
C. Bardier, D. Székely, Guilherme Augusto-Alves, Nicolás Matínez-Latorraca, B. Schmidt, S. Cruickshank   +5 more
semanticscholar   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Validity of photo-identification technique to analyze natural markings in Melanophryniscus montevidensis (Anura: Bufonidae)

Phyllomedusa: Journal of Herpetology, 2014
Individual identification is useful for answering a variety of biological questions about animal life histories. Most of the techniques used to mark amphibians are invasive and can cause negative effects, compromising individual survivorship and biasing ...
Ernesto Elgue, Gisela Pereira, Federico Achaval-Coppes, Raúl Maneyro   +3 more
doaj   +3 more sources

First evidence of bidirectional exchange between distant humpback whale breeding populations in eastern Australia and Brazil [PDF]

Royal Society Open Science
Movements between humpback whale (Megaptera novaeangliae) breeding stocks are exceedingly rare, and exchange between distant breeding grounds in both directions has not previously been documented between eastern Australia and Brazil. Using 19 283 curated
Cristina Castro Ayala, Stephanie H. Stack, Milton C. C. Marcondes, Julio Cardoso, Ted Cheeseman, Jens J. Currie, Arlaine Francisco, Marilia Olio, Bianca Righi, Silke Stuckenbrock, Renata S. Sousa-Lima   +10 more
doaj   +1 more source

Photo-identification of individual Southern Hemisphere humpback whales (Megaptera novaeangliae) using all available natural marks:

, 2020
Misidentification errors in capture-mark recapture studies of humpback whales (Megaptera novaeangliae) related to poor quality of photographs as well as changes in natural marks can seriously affect population dynamics parameter estimates and derived ...
W. Franklin, T. Franklin, P. Harrison, L. Brooks   +3 more
semanticscholar   +1 more source