Results 221 to 230 of about 8,958 (245)

Aligned Conductive Magnetic Nanofibers with Directional Magnetic Field Stimulation Promotes Peripheral Nerve Regeneration

Advanced Science, Volume 12, Issue 37, October 6, 2025.
Peripheral nerve injury necessitates alternatives to autografts. This study combines magnetic nanoparticles, oriented PCL fibers, and Ppy to create a conductive, magnetically active scaffold. In vitro and in vivo experiments demonstrated enhanced downstream pathways of calcium signaling, as revealed by transcriptome analysis.
Zheyuan Fan, Wei Yu, Xinggui Wen, Xiangdong Ding, Xiang Li   +4 more
wiley   +1 more source

Boron Difluoride Formazanate Dye With Donor Planarization Engineering for 1060 nm Laser Activated Photothermal Theranostics

Advanced Science, Volume 12, Issue 37, October 6, 2025.
The donor engineering strategy enhances the planarity of the π‐conjugated molecular framework, thereby promoting stronger intramolecular charge transfer (ICT). This structural refinement in FBDFDPA leads to a pronounced bathochromic shift in absorption from the NIR‐I to the NIR‐II region, enabling effective photothermal therapy (PTT) for tumors within ...
Kang Xu, Mengchen Luo, Weili Wang, Tian Zhang, Yang Chen, Jinjun Shao, Peng Chen, Xiaochen Dong, Yu Cai   +8 more
wiley   +1 more source

Confocal Raman microspectroscopy for spatially resolved tissue characterisation of disease‐linked spectra‐pathological signatures

Clinical and Translational Medicine, Volume 15, Issue 10, October 2025.
Confocal Raman microspectroscopy for spatially resolved tissue analysis: technology setup, spectra‐pathological signatures derived from computational methods, and tissue‐level insights for biomedical research and clinical applications. Abstract Raman spectroscopy is a versatile analytical technique for highly specific molecular characterisation of ...
Nektarios A. Valous, Inka Zörnig, Dirk Jäger   +2 more
wiley   +1 more source

Repurposing the Antidepressant Sertraline: A Systematic Scoping Review of Its Anticancer Mechanisms

Pharmacology Research &Perspectives, Volume 13, Issue 5, October 2025.
A multi‐targeted antidepressant with strong preclinical anticancer activity, sertraline represents a candidate for therapeutic repurposing. ABSTRACT Drug repurposing offers a cost‐effective and time‐efficient strategy for identifying new cancer therapies. Sertraline, a widely prescribed selective serotonin reuptake inhibitor (SSRI), has shown promising
Ciara B. Blum, McCarlie‐Jayne Dohrmann, Lucia McCarthy, Milli McMenamin, Liam A. O'Callaghan   +4 more
wiley   +1 more source

Synthetic Biology and Biomaterials Strategies to Deceive the Tumor Microenvironment in CAR‐T Immunotherapy

Small, Volume 21, Issue 39, October 2, 2025.
A. Synthetic biology and biomaterials have emerged as tools to study and facilitate the treatment of solid tumors wi‐th chimeric antigen receptor‐CAR‐T cells. These strategies aim to resist the tumor microenvironment‐TME that presents cellular, biochemical, and mechanical immunosuppressive signals that hinder CAR‐T efficacy. B.
Grazia Marsico, Sudarshan GC, Velia Siciliano   +2 more
wiley   +1 more source

Illuminating the Unseen: Dynamic Butyrylcholinesterase Detection Driving Precision Medicine and Environmental Toxicology

SmartMat, Volume 6, Issue 5, October 2025.
Butyrylcholinesterase (BChE), a key member of the cholinesterase family, plays an indispensable role in neural signal regulation, Alzheimer's disease therapeutic development, metabolic homeostasis, and clinical toxicology diagnostics. This study provides a comprehensive review of existing analytical methodologies for BChE detection, along with their ...
Min Liu, Shuaige Bai, Shuai Huang, Ting Luo, Yiyang Zhou, Meihui Liu, Xueping Feng, Wenbin Zeng   +7 more
wiley   +1 more source

Nanozymes in Reactive Oxygen Species‐Dependent Diseases: From Design and Preclinical Studies to Clinical Translation Prospects

Small Structures, Volume 6, Issue 10, October 2025.
Nanozymes emerge as promising therapeutic agents for reactive oxygen species (ROS)‐dependent diseases, offering advantages over traditional biocatalysts through enhanced stability, tunability, and targeting capabilities. This review explores their mechanisms, design strategies, and clinical progress, emphasizing precision medicine potential.
Lihong Zhou, Jingyu Yan, Chenying Cui, Yurong Xu, Kaifang Zhang, Meijun Du, Zhuowei Zhang, Xiuping Wu, Bing Li   +8 more
wiley   +1 more source

Synthesis of Anthraquinone Mono‐ and Diboron Complexes with Near‐Infrared Panchromatic Absorption

Chemistry – A European Journal, Volume 31, Issue 53, September 19, 2025.
Anthraquinone boron complexes bearing β‐iminoenolate ligand(s) exhibit strongly substituent‐dependent absorption properties. Unsubstituted monoboron and diboron complexes show sharp UV–Vis–NIR absorption spectra resulting from increased molecular rigidity induced by boron coordination.
Yasuhiro Kubota, Ayumi Ogasawara, Shota Mizuno, Toshiyasu Inuzuka, Kazumasa Funabiki   +4 more
wiley   +1 more source

Collection on clinical photoacoustic imaging

European Journal of Nuclear Medicine and Molecular Imaging
Vonk, J., Knieling, F., Kruijff, S.
openaire   +3 more sources

A New Hope for Melasma: Long‐Term Clearance With 755‐nm Picosecond Alexandrite Laser and Topical JAK Inhibition

Journal of Cosmetic Dermatology, Volume 24, Issue 10, October 2025.
Ali Al‐Mamoori, Sajjad Ghanim Al‐Badri, Ibrahim Khalil, Wael Al‐Daraji   +3 more
wiley   +1 more source