Results 181 to 190 of about 1,807,104 (196)

Translational Photoacoustic Microscopy

2015
Photoacoustic microscopy (PAM), combining the advantages of optical excitation and of acoustic detection, has been widely used for both structural and functional imaging with scalable resolution and penetration in biological tissues. In this chapter, we provide a detailed discussion on PAM in translational studies. We first summarize the principles and
Zhou, Yong, Wang, Lihong V.
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Ultraviolet photoacoustic remote sensing microscopy

Optics Letters, 2019
Traditional histopathology involves fixing, sectioning, and staining protocols that are time consuming and subject to staining variability. In this Letter, we present ultraviolet photoacoustic remote sensing microscopy, capable of imaging cell nuclei without the need for exogenous stains or labelling. Our reflection mode approach is non-contact and has
Nathaniel J. M. Haven, Kevan L. Bell, Pradyumna Kedarisetti, John D. Lewis, Roger J. Zemp   +4 more
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Virtual Intraoperative surgical photoacoustic microscopy

Opto-Acoustic Methods and Applications in Biophotonics II, 2015
A virtual intraoperative surgical photoacoustic microscopy at 1064 nm wavelength (VISPAM) system was designed and fabricated by integrating a commercial type surgical microscope and laser scanning photoacoustic microscopy (PAM) with a 1064 nm pulsed laser. Based on a simple augmented reality device, VISPAM could simultaneously provide 2D depth-resolved
Changho Lee, Donghyun Lee, Qifa Zhou, Jeehyun Kim, Chulhong Kim   +4 more
openaire   +1 more source

Ultracompact high-resolution photoacoustic microscopy

Optics Letters, 2018
Optical resolution photoacoustic microscopy (ORPAM), benefiting from rich optical contrast, scalable acoustic resolution, and deep penetration depth, is of great importance for the fields of biology and medicine. However, limited by the size and performance of reported optical/acoustic scanners, existing portable/handheld ORPAMs are bulky and heavy ...
Qian Chen, Heng Guo, Tian Jin, Weizhi Qi, Huikai Xie, Lei Xi   +5 more
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Dual Focused Photoacoustic Microscopy

Biomedical Optics 2014, 2014
We developed a dual focused technique for depth extended photoacoustic microscopy (PAM). Employing an improved synthetic-aperture-focusing-technique for the dual focused PAM, the imaging depth can be double extended with 2× improved signal intensity.
Jianbo Tang, Lei Xi, Huabei Jiang
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Variable wavelength photoacoustic microscopy

IEEE Symposium on Ultrasonics, 2002
Imaging with a variable wavelength photoacoustic (PA) microscope is a technique that permits the characterization of surface-improved materials, layered materials, etc. The authors present theoretical and experimental studies of the modulation frequency dependence and the image for a layered sample using a variable-wavelength PA microscope.
Y. Nagata, K. Yamanaka, H. Ogiso, T. Koda   +3 more
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Acoustic resolution photoacoustic microscopy

Biomedical Engineering Letters, 2014
Even if conventional optical imaging systems such as multiphoton microscopy (MPM), confocal microscopy (CM), fluorescence microscopy (FM), and optical coherence tomography (OCT) are regarded as revolutionary microscopic imaging modalities to reveal the inner information of biological tissues with very high spatial resolution, it is inherently ...
Sungjo Park, Changho Lee, Jeesu Kim, Chulhong Kim   +3 more
openaire   +2 more sources

Photoacoustic expansion microscopy of melanosomes

Optics Letters
Optical resolution photoacoustic microscopy (OR-PAM) is a hybrid imaging method for visualizing organelles due to the high spatial resolution and abundant optical contrast. Usually, OR-PAM employs high numerical aperture (NA) objectives and high-frequency ultrasonic detectors to resolve three-dimensional (3D) microstructures of cells.
Tingting Li, Xinrui Gong, Heng Guo, Lei Xi   +3 more
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Optical-resolution photoacoustic microscopy with a needle-shaped beam

Nature Photonics, 2022
Rui Cao, Jing-Song Zhao, Lei Li, Lin Du, Yide Zhang, Yilin Luo, Laiming Jiang, Samuel Davis, Qifa Zhou, A. de la Zerda, Lihong V. Wang   +10 more
semanticscholar   +1 more source

Real-time photoacoustic microscopy

Applied Physics Letters, 1984
A new technique in photoacoustic microscopy is described in which a line scan photoacoustic image is displayed directly on an oscilloscope screen and can be observed to change in real time. The new method differs from conventional photoacoustic microscopy in that the beam position is modulated rather than the beam intensity, so that the spatial ...
openaire   +1 more source