Results 91 to 100 of about 101,669 (297)

Studies of photochemical internalisation: mechanisms and strategies in cancer therapeutics [PDF]

open access: yes, 2010
Photochemical internalisation (PCI) is a technique which enhances targeted drug delivery using light in combination with a photosensitiser. It is a modification of photodynamic therapy (PDT) which involves sub-lethal photodynamic treatment to modify ...
Wang, T.-W.
core  

Non-homogeneous liver distribution of photosensitizer and its consequence for photodynamic therapy outcome

open access: yes, 2010
Background: Photodynamic therapy is mainly used for treatment of malignant lesions, and is based on selective location of a photosensitizer in the tumor tissue, followed by light at wavelengths matching the photosensitizer absorption spectrum.
Mônica Andrioli Caracanhas   +11 more
core   +1 more source

Light‐Activated Ruthenium Nanoclusters Reprogram the Metabolic‐Quorum Sensing Axis for Precision Periodontitis Therapy

open access: yesAdvanced Science, EarlyView.
Under 660 nm visible light, Ru NCs efficiently photocatalyze nitrate‐to‐ammonium conversion and modulate oral nitrogen metabolism. They precisely perturb Veillonella parvula, block its key support to Porphyromonas gingivalis, and exert an “inhibiting without killing” antivirulence effect.
Jing Zhou   +10 more
wiley   +1 more source

Antimicrobial photodynamic therapy for inactivation of biofilms formed by oral key pathogens

open access: yesFrontiers in Microbiology, 2014
With increasing numbers of antibiotic-resistant pathogens all over the world there is a pressing need for strategies that are capable of inactivating biofilm-state pathogens with less potential of developing resistances in pathogens.
Fabian eCieplik   +3 more
doaj   +1 more source

A Plant-derived Anti-nociceptive Spray for Reduction of Pain with Photodynamic Therapy

open access: yes, 2014
Background Photodynamic therapy is an effective tool in the management of some forms of skin cancer and generalized solar dermopathy and can be beneficial in the management of acne vulgaris.
Messieh, Alfonse   +5 more
core   +1 more source

Self‐Sustaining Lactate Depletion Nanoplatform Remodels Tumor Microenvironment and Augments Synergistic Photodynamic/Photothermal/Chemodynamic/Starvation Therapy for Eradication of Colon Cancer

open access: yesAdvanced Science, EarlyView.
The HILA nanoplatform integrates HMnO2, LOX, and ICG to orchestrate multimodal therapy (starvation, chemodynamic, photodynamic, and photothermal) for achieving efficient colon cancer eradication. The established HMnO2‐LOX catalytic cycle continuously consumes lactate, acidifys microenvironment, relieves hypoxia, and generats reactive oxygen species ...
Yu‐E. Wang   +11 more
wiley   +1 more source

Diode Laser and Red-Laser Photodynamic Therapy with Toluidine Blue Gel for the Treatment of Onychomycosis: A Case Series

open access: yesMicrobiology Research
Background: Onychomycosis is the most prevalent nail disease, posing a challenge for health professionals in terms of treatment. Conventional topical antifungal treatments can often prove insufficient, and the use of oral antifungal drugs carries a high ...
Sara García-Oreja   +5 more
doaj   +1 more source

Biomimetic Nanoplatform for Dual Target Nano‐Metabolic Therapy in Diabetes‐Associated Biofilm Infections

open access: yesAdvanced Science, EarlyView.
A biomimetic GOx/Arg‐loaded nanoplatform produces nitric oxide through an in situ catalytic cascade reaction, enabling dual‐target metabolic regulation in diabetes‐associated biofilm infections. Bacterial metabolism is disrupted, and macrophage immunometabolism is reprogrammed, resulting in biofilm eradication, immune restoration, and enhanced ...
Mingzhang Li   +13 more
wiley   +1 more source

The use of photosensitizers in photodynamic therapy

open access: yes, 2015
Number of studies and advances in health has been made in the discovery of new photosensitizers (PS) proposed as potentially useful in photodynamic therapy (PDT) for the treatment of various diseases.
Silva, Michelle Peneluppi   +1 more
core   +1 more source

Photodynamic therapy in the esophagus

open access: yesPhotodiagnosis and Photodynamic Therapy, 2004
Photodynamic therapy (PDT) involves in situ photo-activation of photosensitizers by light at appropriate wavelength, generating highly active singlet oxygen and free radicals. For esophageal mucosal dysplasia such as high-grade dysplasia or intramucosal cancer, curative endoluminal therapy including PDT is now a reality.
Shou-Jiang, Tang, Norman E, Marcon
openaire   +2 more sources

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