Results 131 to 140 of about 528 (169)

The bystander effect in photodynamic inactivation of cells

Biochimica et Biophysica Acta (BBA) - General Subjects, 2000
Treatment of MDCK II cells with the lipophilic photosensitizer tetra(3-hydroxyphenyl)porphyrin and light was found to induce a rapid apoptotic response in a large fraction of the cells. Furthermore, the distribution of apoptotic cells in microcolonies of eight cells was found to be different from the binomial distribution, indicating that the cells are
J, Dahle, S, Bagdonas, O, Kaalhus, G, Olsen, H B, Steen, J, Moan   +5 more
openaire   +2 more sources

Photodynamic Inactivation of Herpes Simplex Keratitis

Archives of Ophthalmology, 1974
Bilateral herpes simplex keratitis was induced in rabbit corneas. The infected corneas were treated with either neutral red dye followed by exposure to fluorescent light or with idoxuridine ointment. Dye-light treatment produced a faster cure rate than idoxuridine.
C S, Tara, J A, Stanley, L S, Kucera, S, Hollis   +3 more
openaire   +2 more sources

Light sources for photodynamic inactivation of bacteria

Lasers in Medical Science, 2008
Bacteria have an important role in human and animal morbidity, and a great number of them have developed antibiotic resistance. In the past recent years a new way of dealing with this problem has been studied: photodynamic inactivation. This method is based on administration of a photosensitizing substance that fixes itself in the bacterial cell ...
Mihaela Antonina, Calin, S V, Parasca
openaire   +2 more sources

Fullerene Derivatives in Photodynamic Inactivation of Microorganisms

2017
Fullerene derivatives are accepted as nanoparticles with several potential biomedical applications. The combination of visible light absorption and a long lifetime of triplet excited state allow fullerenes to act as efficient photosensitizers.
Spesia, Mariana Belen, Milanesio, María Elisa, Durantini, Edgardo Néstor   +2 more
openaire   +2 more sources

Dye‐sensitized photodynamic inactivation of cells

Medical Physics, 1981
Living cells may be modified in diverse ways by the combined action of visible light and photosensitizing molecules. The effects appear most frequently as disruptions of subcellular structure, changes in surface membrane function or inhibition of mitotic ability. This review concentrates on the four most thoroughly studied cell types—yeast cells, nerve
J P, Pooler, D P, Valenzeno
openaire   +2 more sources

Photodynamic Inactivation of Infectious Nucleic Acid

Science, 1960
Tobacco mosaic virus-infectious nucleic acid causes a color shift when combined with acridine orange, methylene blue, and safranine. A high concentration of acridine orange inactivates infectious nucleic acid even in darkness, while a mixture of nucleic acid with a low concentration of the dye must be exposed to visible light prior to inoculation for ...
openaire   +2 more sources

Photodynamic inactivation of fibroblasts by a cationic porphyrin

Lasers in Medical Science, 2005
An important determinant of the clinical applicability and value of antimicrobial photodynamic inactivation (PDI) is the cytotoxicity of the treatment to human cells. We evaluated the in vitro cytotoxicity of PDI to human dermal fibroblasts using 5-phenyl-10,15,20-tris(N-methyl-4-pyridyl)porphyrin chloride (TriP[4]) as the photosensitiser.
Lambrechts, Saskia A. G., Schwartz, Kevin R., Aalders, Maurice C. G., Dankert, Jacob B.   +3 more
openaire   +3 more sources

PHOTODYNAMIC INACTIVATION OF AN ION CHANNEL: GRAMICIDIN A

Photochemistry and Photobiology, 1992
Abstract— The ion channel formed by the peptide gramicidin A in planar lipid membranes is inactivated by visible light in the presence of the photosensitizer Rose Bengal. This is concluded from the strong decrease of the membrane conductance by more than two orders of magnitude.Experiments performed at different oxygen concentrations, in the presence ...
M, Strässle, G, Stark
openaire   +2 more sources

Reactivation of photodynamically inactivated lambda phages

Molecular and General Genetics MGG, 1968
UV-irradiated λc phages show a lower survival when plated on rec −-cells as compared to rec +-cells. Photodynamically inactivated λc phages show the lowest survival on hcr −; rec −-cells. The rec-functions do not influence the repair of UV- or photodynamically induced lesions in T1 phages.
openaire   +2 more sources

Photodynamic inactivation of Junin virus

Medical Microbiology and Immunology, 1986
M, Fernández Cobo, E L, Pasian, Z M, de Martínez Segovia   +2 more
openaire   +2 more sources