Results 51 to 60 of about 587,022 (279)

Properties of halogenated and sulfonated porphyrins relevant for the selection of photosensitizers in anticancer and antimicrobial therapies. [PDF]

PLoS ONE, 2017
The impact of substituents on the photochemical and biological properties of tetraphenylporphyrin-based photosensitizers for photodynamic therapy of cancer (PDT) as well as photodynamic inactivation of microorganisms (PDI) was examined. Spectroscopic and
Barbara Pucelik, Robert Paczyński, Grzegorz Dubin, Mariette M Pereira, Luis G Arnaut, Janusz M Dąbrowski   +5 more
doaj   +1 more source

Photodynamic inactivation of influenza virus as a potential alternative for the control of respiratory tract infections

Journal of Photochemistry and Photobiology, 2021
Over the last centuries, the influenza virus has been the cause of one of the deadliest and most concerning respiratory tract infections. Besides being annually responsible for thousands of deaths worldwide, it's capable of originating pandemics that can
Rafael T. Aroso, Giusi Piccirillo, Zoe A. Arnaut, Andreia C.S. Gonzalez, Fábio M.S. Rodrigues, Mariette M. Pereira   +5 more
doaj   +1 more source

Conjugated Porphyrin Polymer With Superior Charge Transfer for Photodynamic‐Immunomodulatory Prevention of CIED Infection in Diabetes

Advanced Healthcare Materials, EarlyView.
Under NIR irradiation, PTCPP generates ROS to eliminate MRSA biofilms and promote M1 macrophage polarization for phagocytosis. After bacterial clearance, the material is phagocytosed by macrophages, shifting their polarization to M2 phenotype via metabolic reprogramming, which synergistically enhances anti‐infection therapy and wound healing.
Honghao Ma, Jinguo Xu, Rongrong Gu, Chuanhui Dong, Te Chen, Yi Mu, Jing Zhu, Yating Wang, Wen Wang, Yingying Zhang, Hongyu Ma, Xiaochen Wang, Sheng Ye, Cheng Cheng   +13 more
wiley   +1 more source

Photodynamic effectiveness of laser diode combined with ozone to reduce STaphylicoccus aureus biofilm with exogenous chlorophyll of Dracaena angustifolia leaves

Biomedical Photonics, 2019
Photodynamic inactivation is an effective treatment that uses light irradiation, photosensitizer and oxygen. The aim of this study was to determine photodynamic effectiveness of laser diode combined with ozone to reduce Staphylococcus aureus biofilm ...
S. D. Astuti, N. D. Drantantiyas, A. P. Putra, P. S. Puspita, A. Syahrom, S. Suhariningsih   +5 more
doaj   +1 more source

A Naphthalimide‐Based NIR‐Emissive AIE Photosensitizer for Synergistic Apoptosis/Ferroptosis‐Mediated Antitumor Therapy and Broad‐Spectrum Bacterial Inactivation With Rapid Wound Healing

Advanced Healthcare Materials, EarlyView.
An ionic naphthalimide AIE photosensitizer (PS), TPAPV‐NIM‐M, anchors to cellular and bacterial membranes, emits in the far‐red/near‐infrared (NIR) region, and efficiently generates reactive oxygen species (ROS) under white light. Its membrane‐localized photodynamic action drives apoptosis/ferroptosis‐mediated tumor suppression and broad‐spectrum ...
Sayed Mir Sayed, Zeeshan Tahir, Fahri Alkan, Yavuz Nuri Ertas   +3 more
wiley   +1 more source

Fluorescence Imaging and Photodynamic Inactivation of Bacteria Based on Cationic Cyclometalated Iridium(III) Complexes with Aggregation‐Induced Emission Properties

Advanced Healthcare Materials, 2021
Antibacterial photodynamic therapy (PDT) is one of the emerging methods for curbing multidrug‐resistant bacterial infections. Effective fluorescent photosensitizers with dual functions of bacteria imaging and PDT applications are highly desirable.
Po-Yu Ho, Sin-Ying Lee, C. Kam, Junfei Zhu, G. Shan, Yuning Hong, W. Wong, Sijie Chen   +7 more
semanticscholar   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Synthesis, Photophysical Characterization, and Photoinduced Antibacterial Activity of Methylene Blue-loaded Amino- and Mannose-Targeted Mesoporous Silica Nanoparticles

Molecules, 2015
Over the last 20 years, the number of pathogenic multi-resistant microorganisms has grown steadily, which has stimulated the search for new strategies to combat antimicrobial resistance. Antimicrobial photodynamic therapy (aPDT), also called photodynamic
Oriol Planas, Roger Bresolí-Obach, Jaume Nos, Thibault Gallavardin, Rubén Ruiz-González, Montserrat Agut, Santi Nonell   +6 more
doaj   +1 more source

Staphylococcus aureus Tolerance and Genomic Response to Photodynamic Inactivation

Msphere, 2021
Staphylococcus aureus can cause disease at most body sites, with illness ranging from asymptomatic infection to death. The increasing prevalence of antibiotic-resistant strains results in treatment failures and high mortality rates. S.
Sara B. Snell, A. Gill, C. Haidaris, T. Foster, T. Baran, S. Gill   +5 more
semanticscholar   +1 more source

Mitochondria and Neuromast Tagging With Fluorescent Gallium‐Triapine Analogues: In Cellulo MP FLIM and Zebrafish Live Imaging

Advanced Science, EarlyView.
Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green, Michael W. Jones, Merissa Saleem, Haobo Ge, Melita Tvardauskaite, Julia Dudzic, Fernando Cortezon‐Tamarit, Rory L. Arrowsmith, Charareh Pourzand, Gabriele Kociock‐Kohn, Nicholas H. Rees, Jonathan R. Dilworth, Stephen Faulkner, Stanley W. Botchway, David Gurevich, Sofia I. Pascu   +15 more
wiley   +1 more source