Results 241 to 250 of about 4,660,211 (356)

Combined Antibiotic and Photodynamic Therapies in Pseudomonas aeruginosa: From Synergy to Antagonism

Amanda C. Zangirolami, Yerra Koteswara Rao, Vladislav V. Yakovlev, Kate Cristina Blanco, Vanderlei Salvador Bagnato   +4 more
openalex   +1 more source

Aggregation‐Induced Triplet Symmetry‐Breaking Charge Separation Drives Electron Transfer for Autophagy Blockade‐Enhanced Type‐I Photodynamic Therapy

Aggregate, EarlyView.
This study presents a novel class of cyanine‐based photosensitizers (PS) to achieve controllable switching between Type‐I and Type‐II mechanisms during photodynamic therapy. The formation of radical ion pairs (PS•+−PS•−) via symmetry‐breaking charge separation in aggregated systems at the triplet state, triggering Type‐I cascade reactions for effective
Xin Li, Fuping Han, Xiao Zhou, Hongyi Zhang, Tiancong Shi, Lihan Cai, Danhong Zhou, Weijie Chi, Saran Long, Wen Sun, Jianjun Du, Jiangli Fan, Xiaojun Peng   +12 more
wiley   +1 more source

Aggregation‐Enhanced Asymmetric Heptamethine Cyanine Nanoplatform for Imaging‐Guided Synergistic Phototherapy and Ferroptosis

Aggregate, EarlyView.
An asymmetric heptamethine cyanine photosensitizer, Cyp‐TPE, is designed to break molecular symmetry and form ordered nanoaggregates, resulting in ultrahigh ROS generation and synergistic photothermal/photodynamic activity. It further triggers ferroptosis and lysosomal dysfunction, providing a potent aggregate‐based theranostic platform for imaging ...
Mengyuan Cui, Wenqing Li, Yanli Chen, Huijia Liu, Li Liu, Min Ji, Peng Wang   +6 more
wiley   +1 more source

Peri-Implant Diseases: Enhanced Antibacterial Photodynamic Therapy. [PDF]

Clin Exp Dent Res
Lähteenmäki H, Pätilä T, Räisänen IT, Kalliala R, Sorsa T.   +4 more
europepmc   +1 more source

Bacterial DNA‐Targeting AIE Photosensitizer for Efficient Eradication of Intracellular Bacteria and Biofilm‐Associated Infections

Aggregate, EarlyView.
A bacterial DNA‐targeted PS TPE‐CN for the precise treatment of MRSA‐associated infections has been developed. Through synergistic PDT effect, TPE‐CN damages bacterial DNA and membrane, resulting in effective elimination of planktonic bacteria, biofilm, and intracellular bacteria.
Yonghui Lv, Minyang Zhao, Qiaowen Lin, Zhiwen Xu, Qingqing Bai, Dan Ding, Duo Mao, Kang‐Nan Wang   +7 more
wiley   +1 more source

Subcellular Organelle-Targeted Drug Delivery of Photodynamic Therapy and Gas-Photodynamic Combination Therapy. [PDF]

Int J Nanomedicine
Zhang X, Wang J, Wang S, Fu L, Du X, Rong Q, Yao C, Xin J.   +7 more
europepmc   +1 more source

Immunogenic Cell Death: Can It Be Exploited in PhotoDynamic Therapy for Cancer? [PDF]

, 2012
Elisa Panzarini, Valentina Inguscio, Luciana Dini   +2 more
openalex   +1 more source

AI‐Driven Microphysiological Systems for Advancing Nanoparticle Therapeutics

Advanced Intelligent Systems, EarlyView.
This review outlines recent advances in integrating artificial intelligence with microphysiological systems for nanoparticle evaluation. It highlights data‐driven optimization, image‐based prediction, and AI‐enabled analysis frameworks that advance translational research and support the development of personalized nanomedicine. Nanoparticles (NPs) play
Yedam Lee, Jaehong Min, Sujin Kim, Jihoon Ko   +3 more
wiley   +1 more source

Rose bengal photodynamic antimicrobial therapy to inhibit Pseudomonas aeruginosa keratitis isolates

, 2019
Heather Durkee, Alejandro Arboleda, Mariela C Aguilar, Jaime D. Martinez, Karam A. Alawa, Nidhi Relhan, Jorge Maestre-Mesa, Guillermo Amescua, Darlene Miller, Jean–Marie Parel   +9 more
openalex   +2 more sources

Rod‐Like PLGA Microrobots with Enhanced Motion and Biodegradation for Magnetic‐Guided Drug Delivery

Advanced Intelligent Systems, EarlyView.
This study presents drug‐loaded Poly (lactic‐co‐glycolic acid) (PLGA) microrobots fabricated from an oil‐in‐water (O/W) emulsion of PLGA, Fe3O4 nanoparticles, and Adriamycin (DOX). They are formed by film‐forming and stretching microrobots, and exhibit motion analyzed via video‐snapshots, speed graphs, and shape changes, advancing targeted for drug ...
Junkai Zhang, Yukun Zhong, Zihao Chu, Xinran Geng, Zerui Li, Hongxi Yin, U Kei Cheang   +6 more
wiley   +1 more source