Results 71 to 80 of about 2,597,479 (292)

Photodynamic therapy characteristics of phthalocyanines in the presence of boron doped detonation nanodiamonds [PDF]

, 2022
The synthesis, photophysicochemical and photodynamic therapy (PDT) activities of benzothiazole substituted zinc phthalocyanine (Pc): 1 (asymmetrically substituted and composed of no charges), 2 (asymmetrically substituted and composed of three positive ...
Nyokong, Tebello, Chen, Zhi-Long, Matshitse, Refilwe, Managa, Muthimuni, Nwaji, Njemuwa, Njemuwa Nwaji, Zhi-Long Chen, Refilwe Matshitse, Muthumuni Managa, Tebello Nyokong   +9 more
core   +1 more source

ROS Self‐Supply Nanoplatform Based on Fenton Catalyst for Chemodynamic and Immunotherapy: Reprogramming Cold Tumor Into Hot Tumor in Cancer Treatment

Advanced Science, EarlyView.
A multifunctional HA‐conjugated nanoplatform (HA‐PGMC) integrates CuO2, glucose oxidase, and mil‐100 to enable cascade catalytic ROS generation in tumor microenvironments. This self‐supplying ROS strategy induces immunogenic cell death, reprograms “cold” tumors into “hot” ones, and synergizes with PD‐L1 blockade, achieving potent chemodynamic ...
Man Lung Lee, Jack Chun Hin Chen, Wai Wing Cheng, Kwan Yee Lau, Hiu Yee Kwan, Ngar‐Yun Ellen Poon, Hung‐Wing Li   +6 more
wiley   +1 more source

Repetitive Daylight Photodynamic Therapy versus Cryosurgery for Prevention of Actinic Keratoses in Photodamaged Facial Skin: A Prospective, Randomized Controlled Multicentre Two-armed Study

Acta Dermato-Venereologica, 2021
Actinic keratoses are a chronic condition in ultraviolet-damaged skin, with a risk of progressing to invasive skin cancer. The aim of this study was to investigate the preventive potential of field-directed repetitive daylight photodynamic therapy for ...
Sigrid Karrer, Rolf-Markus Szeimies, Wolfgang G. Philipp-Dormston, Peter A. Gerber, Welf Prager, Elisabeth Datz, Florian Zeman, Karolina Müller, Michael Koller   +8 more
doaj   +1 more source

Photodynamic therapy in the esophagus

Photodiagnosis and Photodynamic Therapy, 2004
Photodynamic therapy (PDT) involves in situ photo-activation of photosensitizers by light at appropriate wavelength, generating highly active singlet oxygen and free radicals. For esophageal mucosal dysplasia such as high-grade dysplasia or intramucosal cancer, curative endoluminal therapy including PDT is now a reality.
Shou-Jiang, Tang, Norman E, Marcon
openaire   +2 more sources

A Molecular Engineering Strategy to Fine‐Tune Phototoxicity of AIE Probes for Super‐Resolution Imaging of Mitochondrial Cristae Dynamics

Advanced Science, EarlyView.
Regulation of molecular packing, phototoxicity, and ROS output of AIE photosensitizers is achieved through carboxylation and alkyl‐chain‐length tuning. The probe designed via this strategy enables super‐resolution visualization of inner‐mitochondrial‐membrane cristae dynamics under controlled oxidative stress, and fluorescence‐lifetime imaging of ...
Kongqi Chen, Mengjie Wang, Chuen Kam, Zhiming Wang, Qinrong Zhang, Sijie Chen   +5 more
wiley   +1 more source

Non-homogeneous liver distribution of photosensitizer and its consequence for photodynamic therapy outcome

, 2010
Background: Photodynamic therapy is mainly used for treatment of malignant lesions, and is based on selective location of a photosensitizer in the tumor tissue, followed by light at wavelengths matching the photosensitizer absorption spectrum.
Mônica Andrioli Caracanhas, VOLLET-FILHO, Jose Dirceu, CARACANHAS, Monica Andrioli, FERREIRA, Juliana, Clóvis Grecco, GRECCO, Clovis, Vanderlei Salvador Bagnato, Juliana Ferreira, KURACHI, Cristina, BAGNATO, Vanderlei Salvador, Cristina Kurachi, José Dirceu Vollet-Filho   +11 more
core   +1 more source

Review of Gastrointestinal Capsule Robots: Materials, Actuation, Diagnostics, and Therapeutics

Advanced Science, EarlyView.
This review examines gastrointestinal capsule robots through a systems engineering lens, covering shell materials, actuation and localization strategies, diagnostic modalities, therapeutic interventions, and commercialization status. By mapping the complete technological chain from fabrication to clinical deployment, this work identifies critical gaps ...
Zengsheng Li, Zhongguo Ren, Yiliang Lin, Xianfeng Xia, Tianlong Li, Kai Fung Chan, Philip Wai Yan Chiu, Wei Peng Yong, Mengmeng Sun   +8 more
wiley   +1 more source

Photodynamic therapy in Argentina

Photodiagnosis and Photodynamic Therapy, 2006
The use of endogenous Protoporphyrin IX generated through the heme biosynthetic pathway after administration of 5-aminolevulinic acid (ALA) has led to many applications in photodynamic therapy (PDT). In Buenos Aires, Argentina, the Centro de Investigaciones sobre Porfirinas y Porfirias (CIPYP), reported for the first time, in 1975, porphyrin synthesis ...
Adriana, Casas, Alcira, Batlle
openaire   +2 more sources

Genetic deviation associated with photodynamic therapy in HeLa cell

, 2023
Photodynamic therapy (PDT) is a method that is used in cancer treatment. The main therapeutic effect is the production of singlet oxygen (1O2). Phthalocyanines for PDT produce high singlet oxygen with absorbers of about 600-700 nm.
Okat, Zehra, Gök Yurttaş, Asiye, Elgün, Tuğba, Uçar Çifçi, Kexban, Tugba ELGUN, Asiye GOK YURTTAS, Zehra OKAT, Gül, Ahmet, Çiftci, Kezban Uçar, Sevim, Altug Mert, Yurttaş, Asiye Gök, Altug Mert SEVIM, Kezban UCAR CİFCİ, CİFCİ, KEZBAN, Uçar Çifçi, Kezban, Ahmet GUL   +15 more
core   +1 more source

Modification‐Selective Inhibition of Succinate Dehydrogenase a Enables Tumor‐Restricted Mitochondrial Modulation

Advanced Science, EarlyView.
This work identifies acetylation‐dependent SDHA homeostasis as a determinant of tumor‐specific metabolic vulnerability. Guided by this mechanism, a modification‐selective inhibitor, ZPI‐3, selectively targets non‐acetylated SDHA, achieving tumor‐restricted SDH inhibition and effective bladder cancer control. Differential responses in clinical specimens
Kaikai Xu, Lulu Kong, Kebin Ye, Xinlu Bao, Haowen Liu, Ning Wang, Yongming Deng, Wei Wang, Shaohua Wei, Lin Zhou   +9 more
wiley   +1 more source