Results 71 to 80 of about 5,289,516 (392)

Cancer targeting with biomolecules: a comparative study of photodynamic therapy efficacy using antibody or lectin conjugated phthalocyanine-PEG gold nanoparticles [PDF]

, 2015
The functionalisation of therapeutic nanoparticle constructs with cancer-specific biomolecules can enable selective tumour accumulation and targeted treatment. Water soluble gold nanoparticles (ca.
Allen, Arap, Bechet, Bertrand, Boya, Bullous, David A. Russell, Davis, Dougherty, Gary-Bobo, Girgis Obaid, Hamblin, Harris, Hogemann-Savellano, Hone, Isabelle Chambrier, Iversen, Jeyaprakash, Jin, Kim, Konska, Kopeček, Lindig, Marín, Mew, Michael J. Cook, Obaid, Oleinick, Orlova, Poiroux, Qualls, Robertson, Ross, Schafer, Schrama, Slamon, Spring, Springer, Stuchinskaya, Sudimack, Tang, Vacha, Wang, Weissenbock, Wieder, Xu, Yarden, Yu, Yu, Zhang   +49 more
core   +1 more source

Sonodynamic therapy with chemo-radiotherapy in high-grade brainstem gliomas: A prospective phase IIa clinical trial

Photodiagnosis and Photodynamic Therapy
The treatment of high-grade brainstem gliomas (HBSGs), which are a type of malignant neoplasm, is challenging. There is a need to develop novel and effective therapeutic approaches for HBSGs. This study analyzed the data between sonodynamic therapy (SDT)
Xiaohao Liu, Linkuan Huangfu, Long Wang, Jiayin Ding, Tianqi Li, Yahang Liu, Yue Yu, Miaomiao Zhang, Zhifei Dai, Yingjuan Zheng   +9 more
doaj   +1 more source

Key Role of Human ABC Transporter ABCG2 in Photodynamic Therapy and Photodynamic Diagnosis

Advances in Pharmacological Sciences, 2010
Accumulating evidence indicates that ATP-binding cassette (ABC) transporter ABCG2 plays a key role in regulating the cellular accumulation of porphyrin derivatives in cancer cells and thereby affects the efficacy of photodynamic therapy and photodynamic ...
Toshihisa Ishikawa, Hiroshi Nakagawa, Yuichiro Hagiya, Naosuke Nonoguchi, Shin-ichi Miyatake, Toshihiko Kuroiwa   +5 more
doaj   +1 more source

Dual Role of Subphthalocyanine Dyes for Optical Imaging and Therapy of Cancer [PDF]

, 2018
This is the peer-reviewed version of the following article: van de Winckel, E., Mascaraque, M., Zamarrón, A., Juarranz de la Fuente, Á., Torres, T., & de la Escosura, A. (2018).
Escosura Navazo, Andrés de la, Juarranz de la Fuente, Ángeles, Mascaraque Checa, Marta, Torres Cebada, Tomás, van de Winckel, Eveline, Zamarrón, Alicia   +5 more
core   +1 more source

Solutions to the Drawbacks of Photothermal and Photodynamic Cancer Therapy

Advancement of science, 2021
Phototherapy such as photothermal therapy and photodynamic therapy in cancer treatment has been developed quickly over the past few years for its noninvasive nature and high efficiency. However, there are still many drawbacks in phototherapy that prevent
Xiangyu Deng, Zengwu Shao, Yanli Zhao
semanticscholar   +1 more source

Photodynamic Therapy of Necrobiosis Lipoidica - A Multicenter Study of 18 Patients [PDF]

, 2008
Background: Necrobiosis lipoidica (NL) is a granulomatous skin disease of unknown origin, and no reliably effective treatment option exists to handle this often disfiguring disease.
Arenberger, P., Berking, C., Hegyi, J., Jemec, G. B. E., Ruzicka, Thomas   +4 more
core   +1 more source

Multi‐Functional Liposome: A Powerful Theranostic Nano‐Platform Enhancing Photodynamic Therapy

Advancement of science, 2021
Although photodynamic therapy (PDT) has promising advantages in almost non‐invasion, low drug resistance, and low dark toxicity, it still suffers from limitations in the lipophilic nature of most photosensitizers (PSs), short half‐life of PS in plasma ...
Xiamin Cheng, Jing Gao, Yang Ding, Yao Lu, Qiancheng Wei, Dezhi Cui, Jiali Fan, Xiaoman Li, Ershu Zhu, Yongna Lu, Qiong Wu, Lin Li, Wei Huang   +12 more
semanticscholar   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Susceptibility and Resistance Mechanisms During Photodynamic Therapy of Melanoma

Frontiers in Oncology, 2020
Melanoma is the most aggressive malignant skin tumor and arises from melanocytes. The resistance of melanoma cells to various treatments results in rapid tumor growth and high mortality.
Xin-Ying Li, Liu-Chang Tan, Li-Wen Dong, Wan-Qi Zhang, Xiao-Xiao Shen, Xiao Lu, Hong Zheng, Yuan-Gang Lu   +7 more
doaj   +1 more source

Gold Nanorod-Decorated Metallic MoS₂ Nanosheets for Synergistic Photothermal and Photodynamic Antibacterial Therapy

Nanomaterials, 2021
Light-responsive nanocomposites have become increasingly attractive in the biomedical field for antibacterial applications. Visible-light-activated metallic molybdenum disulfide nanosheets (1T-MoS2 NSs) and plasmonic gold nanorods (AuNRs) with absorption
Sibidou Yougbaré, Chinmaya Mutalik, Pei-Feng Chung, Dyah Ika Krisnawati, Fajar Rinawati, Hengky Irawan, Heny Kristanto, Tsung-Rong Kuo   +7 more
doaj   +1 more source