Results 101 to 110 of about 240,809 (322)

Adenylyl Cyclase 8 in Dorsal CA1 Neurons Prevents Depressive‐Like Behaviors by Maintaining Neuronal Excitability and Glutamatergic Neurotransmission Through TIP39‐PTH2R Signaling

Advanced Science, EarlyView.
Depression, a prevalent neuropsychiatric disorder with unclear pathogenesis, involves dysfunctional adenylyl cyclase 8 (Adcy8) as a key risk factor. Chronic stress selectively reduces Adcy8 expression in the dorsal CA1 (dCA1) neurons. Depletion of Adcy8 in dCA1 excitatory neurons induces depressive‐like behaviors by impairing neuronal excitability and ...
Zi‐Jie Liu, Jia‐Rui Bi, Zong‐Yan Yu, Meng Tian, Zhi‐Yue Chen, Ran Wei, Miao‐Miao Wang, Hai‐Wei Zha, Yu‐Qing Zhang, Hong‐Jing Wang, Bang‐You Qiang, Shuang‐Shuang Sun, Xiao‐Juan Zhu, Wen‐Bing Chen, Dong Sun   +14 more
wiley   +1 more source

Impact of photometric variability on age and mass determination of Young Stellar Objects: A case study on Orion Nebula Cluster

, 2015
In case of pre-main sequence objects, the only way to determine age and mass is by fitting theoretical isochrones on color-magnitude (alternatively luminosity-temperature) diagrams.
Messina, Sergio, Parihar, Padmakar S., Distefano, Elisa   +2 more
core  

Astrocytic PCBP1 Suppresses Ferroptosis to Restore Glutamatergic Homeostasis and Mitigate Stress‐Induced Depression in Male Mice

Advanced Science, EarlyView.
This study demonstrates that polyC‐RNA‐binding protein 1 (PCBP1) in ventral hippocampal astrocytes modulates depressive‐like behaviors by regulating glutathione peroxidase 4‐mediated ferroptosis and synaptic glutamatergic transmission. PCBP1 overexpression intervention in the chronic unpredictable mild stress model rescues behavioral deficits ...
Jinyu Zhang, Binbin Zhao, Min Jia, Yan Zhao, Ye Lu, Wenyu Xi, Ziyu Zhu, Xiaojuan Gong, Qingyan Ma, Yuan Gao, Yijie Guo, Pan Li, Feng Zhu, Shuguang Wei, Xiancang Ma, Yunpeng Wang   +15 more
wiley   +1 more source

M DWARFS IN SLOAN DIGITAL SKY SURVEY STRIPE 82: PHOTOMETRIC LIGHT CURVES AND FLARE RATE ANALYSIS [PDF]

, 2009
Adam F. Kowalski, Suzanne L. Hawley, Eric J. Hilton, A. C. Becker, Andrew A. West, John J. Bochanski, Branimir Sesar   +6 more
openalex   +1 more source

Comprehensive spectroscopic and photometric study of pulsating eclipsing binary star AI Hya [PDF]

, 2023
F. Kahraman Alivacus, T. Pawar, K. G. Hełminiak, G. Handler, A. Moharana, F. Alicavus, P. De Cat, F. Leone, G. Catanzaro, M. Giarrusso, N. Ukita, E. Kambe   +11 more
openalex   +1 more source

Nanoscopic Mapping of the Extracellular Space in Amyloid Plaque‐rich Cortex

Advanced Science, EarlyView.
The extracellular space and diffusion around amyloid plaques are examined using shadow imaging and single‐particle tracking. Increased diffusivity is found near plaques, extracellular matrix alterations, and plaque core penetrability that varies with amyloid phenotype.
Juan Estaún‐Panzano, Yulia Dembitskaya, Ivo Calaresu, Somen Nandi, Quentin Gresil, Evelyne Doudnikoff, Thierry Leste‐Lasserre, Thierry Amédée, Laurent Cognet, Laurent Groc, Urs Valentin Nägerl, Erwan Bezard   +11 more
wiley   +1 more source

Photometry of Variable Stars, and System Transformability Over Long Time Intervals

Open Astronomy, 2003
The fundamental problem of long-term photometric monitoring of variable stars and of multi-wavelength photometric campaigns is the problem of bringing the data to a common standard.
Sterken C.
doaj   +1 more source

Pristine dwarf galaxy survey – I. A detailed photometric and spectroscopic study of the very metal-poor Draco II satellite [PDF]

, 2018
Nicolas Longeard, Nicolas F. Martin, Else Starkenburg, Rodrigo Ibata, Michelle Collins, Marla Geha, Benjamin P. M. Laevens, R. Michael Rich, David S. Aguado, Anke Arentsen, R. G. Carlberg, Patrick Côté, V. Hill, P. Jablonka, J. I. Gónzalez Hernández, Julio F. Navarro, Rubén Sánchez-Janssen, Eline Tolstoy, Kim A. Venn, Kris Youakim   +19 more
openalex   +1 more source

Osmotically Tunable Microdroplets Enable Amplification‐Free CRISPR Detection of Gene Doping

Advanced Science, EarlyView.
A novel amplification‐free clustered regularly interspaced short palindromic repeats/CRISPR‐associated protein (CRISPR/Cas) 12a assay is integrated with osmotically shrinkable double emulsion droplets for the rapid and ultrasensitive detection of gene doping.
Jihun Han, Reya Ganguly, Joon‐Yeop Yi, Hyewon Yun, So‐Yeon Jung, Changmin Sung, Chang‐Soo Lee   +6 more
wiley   +1 more source

SN 2013dx associated with GRB 130702A: a detailed photometric and spectroscopic monitoring and a study of the environment [PDF]

, 2015
V. D’Elia, E. Pian, A. Melandri, P. D’Avanzo, M. Della Valle, P. A. Mazzali, S. Piranomonte, G. Tagliaferri, L. A. Antonelli, F. Bufano, S. Covino, D. Fugazza, D. Malesani, P. Møller, E. Palazzi   +14 more
openalex   +1 more source