Results 141 to 150 of about 316,881 (368)

Photometry of Variable Stars, and System Transformability Over Long Time Intervals

open access: yesOpen Astronomy, 2003
The fundamental problem of long-term photometric monitoring of variable stars and of multi-wavelength photometric campaigns is the problem of bringing the data to a common standard.
Sterken C.
doaj   +1 more source

cGAS Inhibits ALDH2 to Suppress Lipid Droplet Function and Regulate MASLD Progression

open access: yesAdvanced Science, EarlyView.
cGAS is a cytosolic DNA sensor known for innate immune defense. cGAS binds and suppresses ALDH2 are showed, limiting acetyl‐CoA production. cGAS loss activates ALDH2, promoting histone acetylation, lipogenesis, and lipid droplets accumulation. cGas‐/‐ mice on a high‐fat diet show signs of worsened MASLD.
Ying Wang   +14 more
wiley   +1 more source

Impact of photometric variability on age and mass determination of Young Stellar Objects: A case study on Orion Nebula Cluster

open access: yes, 2015
In case of pre-main sequence objects, the only way to determine age and mass is by fitting theoretical isochrones on color-magnitude (alternatively luminosity-temperature) diagrams.
Messina, Sergio   +2 more
core  

LncRNA THUMPD3‐AS1 Regulates Behavioral and Synaptic Structural Abnormalities in Schizophrenia via miR‐485‐5p and ARHGAP8

open access: yesAdvanced Science, EarlyView.
Schizophrenia (SCZ) is linked to synaptic structural deficits driven by dysregulated noncoding RNAs. Using the novel ceRNAxis pipeline, THUMPD3‐AS1/miR‐485‐5p/ARHGAP8 is identified as a key regulator of actin cytoskeletal remodeling through noncanonical RhoB/C‐ROCK2 signaling. Modulating this axis ameliorates SCZ‐like phenotypes in mice and aligns with
Xiaojuan Gong   +9 more
wiley   +1 more source

Photocatalytic Activity of Ionic Carbon Nitrides is Governed by Cation‐Modulated Dark Exciton Dynamics

open access: yesAdvanced Science, EarlyView.
This study establishes a direct link between photocatalytic activity, spectroscopic properties, and theoretical analysis of structural effects on exciton behavior in ionic carbon nitrides with different cations. The exciton lifetimes and photocatalytic activity are shown to be primarily related to different dark exciton dynamics governed by changes in ...
Arindam Konar   +12 more
wiley   +1 more source

Synaptic Dysfunction in the Anterior Cingulate Cortex Underlies Pain‐Anxiety Comorbidity in a Mandibular Asymmetry Mouse Model

open access: yesAdvanced Science, EarlyView.
This study establishes a mandibular asymmetry (MA) mouse model that recapitulates chronic orofacial pain and anxiety comorbidity. Anterior cingulate cortex (ACC) hyperactivation and synaptic dysfunction are identified as central neural mechanisms underlying these pathologies, with chemogenetic inhibition of ACC CaMKII+ neurons effectively reversing ...
Zhaoyichun Zhang   +19 more
wiley   +1 more source

Soil Nutrient Enrichment Induces Trade‐Offs in Bacterial Life‐History Strategies Promoting Plant Productivity

open access: yesAdvanced Science, EarlyView.
Soil nutrient enrichment induces the trade‐offs between bacterial functional potential and growth‐rate potential. Such trade‐offs favor specific plant‐beneficial species and genes, playing a pivotal role in determining plant productivity. These findings enhance the understanding of the microbial responses in agroecosystems to ongoing global ...
Yuanyuan Yan   +5 more
wiley   +1 more source

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