Results 91 to 100 of about 182,753 (279)

Visible and near-infrared observations of asteroid 2012 DA14 during its closest approach of February 15, 2013

, 2013
Near-Earth asteroid 2012 DA14 made its closest approach on February 15, 2013, when it passed at a distance of 27,700 km from the Earth's surface. It was the first time an asteroid of moderate size was predicted to approach that close to the Earth ...
Alvarez-Candal, A., Cabrera-Lavers, A., Cikota, S., de Leon, J., Duffard, R., Licandro, J., Lorenzi, V., Morales, N., Ortiz, J. L., Perez-Romero, A., Pinilla-Alonso, N., Santos-Sanz, P.   +11 more
core   +1 more source

The Crystal Structure of Human Transport and Golgi Organization 2 Homolog (TANGO2) Protein Reveals an αββα‐Fold Arrangement

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Transport and Golgi Organization 2 Homolog (TANGO2) protein deficiency disorder (TDD) is a rare autosomal recessive disorder characterized by multi‐systemic abnormalities and significant phenotypic variability including neurodevelopmental delay, seizures, intermittent ataxia, hypothyroidism, rhabdomyolysis, life‐threatening metabolic ...
Anne Cooper, Alyssa Powers, Kevin P. Battaile, Al‐Walid Mohsen, David K. Johnson, Scott Lovell, Lina Ghaloul‐Gonzalez   +6 more
wiley   +1 more source

Infrared identification of IGR J09026-4812 as a Seyfert 1 galaxy

, 2009
IGR J09026-4812 was discovered by INTEGRAL in 2006 as a new hard X-ray source. Thereafter, an observation with Chandra pinpointed a single X-ray source within the ISGRI error circle, showing a hard spectrum, and improving its high-energy localisation to ...
Barvainis, Bird, Bird, Bodaghee, Glikman, J. A. Tomsick, J. A. Zurita Heras, Landolt, Lebrun, Persson, Pickles, Riffel, Rudy, S. Chaty, Schlegel, Stephen, Tomsick, Ubertini, Winkler   +18 more
core   +2 more sources

Restoring failed inhibition in the substantia nigra pars reticulata suppresses absence seizures in rats

Epilepsia, EarlyView.
Abstract Objective For over four decades, the substantia nigra pars reticulata (SNr) has been recognized as a critical structure in the modulation of seizure activity. Pharmacological and optogenetic inhibition of the SNr produces robust seizure suppression in a range of seizure models.
Devin Palmer, Patrick A. Forcelli
wiley   +1 more source

Structural analysis of the NifL‐NifA complex reveals the molecular basis of anti‐activation of nitrogen fixation gene expression in Azotobacter vinelandii

The FEBS Journal, EarlyView.
Using cryo‐EM combined with biochemical and genetic approaches, we mapped the interaction surface between NifL and NifA to gain insights into the regulation of nitrogen fixation genes in A. vinelandii. Our findings suggest that NifL, a homolog of histidine kinases lacking phosphorylation activity, evolved to act as a steric block of NifA activity ...
Marcelo Bueno Batista, Jake Richardson, Michael W. Webster, Dmitry Ghilarov, John W. Peters, David M. Lawson, Ray Dixon   +6 more
wiley   +1 more source

Combining Aperture and PSF-Fitting Photometry

Open Astronomy, 2003
The multiple object and multiple frame (MOMF) CCD photometry package, that combines the advantages of aperture and PSF photometry is described. Results from comparisons with other programs are given; no other photometry package was found to give better ...
Handler G.
doaj   +1 more source

The fc fragment of IgMs binds C1q to activate the first step of the classical complement pathway, while inhibiting complement‐dependent cytotoxicity

The FEBS Journal, EarlyView.
Multimeric IgM‐fragment crystallizable region (Fc) fragments retain the ability to bind C1q and initiate the classical complement pathway, leading to C4 activation and deposition in vitro. However, the Fc cores can also inhibit complement‐dependent cytotoxicity by competing with surface‐bound antibodies for C1q engagement.
Andrea J. Pinto, Anne Chouquet, Isabelle Bally, Véronique Rossi, Nicole M. Thielens, Chantal Dumestre‐Pérard, Renate Kunert, Christine Gaboriaud, Wai Li Ling, Jean‐Baptiste Reiser   +9 more
wiley   +1 more source

First Results From the Large Binocular Telescope: Deep Photometry of New dSphs

, 2007
This contribution describes photometry for two Galactic dSphs obtained with the Large Binocular Telescope to a magnitude of ~25.5. Using the Large Binocular Camera, a purpose-built wide-field imager for the LBT, we have examined the structure and star ...
A.E. Dolphin, C.J. Grillmair, J.M. Hill, L. Girardi, M.J. Irwin, R. Ragazzoni, V. Belokurov   +6 more
core   +1 more source

Inflammatory and Myocardial Biomarker Response Following Pulmonary Vein Isolation: Cryoballoon Versus Balloon‐in‐Basket Pulsed Field Ablation

Journal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Background Cryoballoon ablation (CB) is a well‐established thermal technique for pulmonary vein isolation (PVI), while balloon‐in‐basket pulsed field ablation (BiB‐PFA) represents a novel non‐thermal alternative. Both single‐shot systems may trigger systemic inflammation and myocardial injury, yet direct comparisons are lacking.
Jan‐Per Wenzel, Sascha Hatahet, Charlotte Eitel, Raed Abdessadok, Sorin Popescu, Julius Nikorowitsch, Suzanne de Waha, Tanja Zeller, Karl‐Heinz Kuck, Roland Richard Tilz   +9 more
wiley   +1 more source

Study of the Time-Series of Microvariability in Kepler Blazar W2R 1926+42

Galaxies, 2017
One of the remarkable features of blazars is violent variability over a wide wavelength range. The variation mechanism causing the observed complex behavior is still under debate.
Mahito Sasada, Shin Mineshige, Shinya Yamada, Hitoshi Negoro   +3 more
doaj   +1 more source