Results 81 to 90 of about 20,857 (202)
Unraveling the active site cover of coproheme decarboxylase from Listeria monocytogenes
During heme biosynthesis in Gram‐positive bacteria, coproheme decarboxylase (ChdC) catalyzes the conversion of four‐propionate substrate coproheme to the two propionate product heme b. Its active site is universally covered by a flexible linking loop. This study identifies an important histidine residue, which stabilizes the loop in a ChdC homolog.
Nikolaus Falb +4 more
wiley +1 more source
ABSTRACT Objectives Criteria for visual examination of stained peripheral blood smear (PBS) differ among institutions in the United States and internationally. In an effort to standardize review criteria, the International Consensus Group for Hematology Review (ICGHR) proposed in 2005 a consensus list of rules for CBC findings that should trigger a ...
Elizabeth L. Courville +14 more
wiley +1 more source
Phenotypic scoring of canola blackleg severity using machine learning image analysis
Abstract Canola blackleg is a fungal disease that causes significant yield loss and plant death of infected canola (Brassica napus L., Brassica rapa L., Brassica juncea L.) fields worldwide. One of the most effective methods for controlling blackleg is through the cultivation of resistant varieties.
Qiao Hu +15 more
wiley +1 more source
Treatment of polypropylene fabric in oxygen plasma was used to impart the fabric surface with more hydrophilic surface properties. Changes in bulk properties were minimal as the modification mainly affected the fabric surface. Bulk fabric properties water retention, moisture content and wicking were monitored over a period of 33 days.
Floriana Constantin +2 more
wiley +1 more source
mGluR5 in ECCCK to BLA Circuit Modulates Depressive‐Like Phenotypes through CCK Signaling
Dysregulation of mGluR5 and CCK signaling contributes to major depressive disorder, yet circuit‐level mechanisms remain unclear. Here, the ECCCK→BLA pathway is identified as a critical regulator of affective behavior. mGluR5 modulates synaptic function and CCK signaling within this circuit, controlling stress susceptibility and depressive‐like states ...
Muhammad Asim +4 more
wiley +1 more source
GK PUA Domain Modulates Cables, Cooperativity, and Proline Feedback
EcGK tetramers hierarchically assemble into metabolic filaments and bundle into metabolic cables. Upon substrate binding, this dynamic equilibrium shifts from inactive cables to active tetramers to drive catalysis; meanwhile the inhibitor proline stabilizes an X‐shaped conformation, redirecting assembly toward filaments to enable efficient feedback ...
Tianyi Zhang +4 more
wiley +1 more source
Linalool odor exposure activates a glutamatergic projection from the piriform cortex to the lateral hypothalamus (PiriGlu‐LH), mediating descending inhibitory pain pathways. This demonstrates a novel neural mechanism for olfactory‐induced pain modulation and suggests potential therapeutic implications for pain management.
Yunhe Zhu +8 more
wiley +1 more source
Research on Physics-Informed Transformer for Space Object Shape Classification
Estimating the shape of space objects helps infer key characteristics such as object type, mass, and potential operational status, thereby providing critical decision-making support for space threat assessment.
Mengci Li +10 more
doaj +1 more source
Cleaning Efficacy of Air Polishing on Tobacco‐Stained Resin Composite: An In‐Vitro Study
ABSTRACT Objective To evaluate the efficacy of air‐polishing on color change and surface roughness of resin composite and enamel specimens after standardized cigarette smoke exposure. Methods Sixty composite/enamel specimens were exposed daily to cigarette smoke in an automated chamber over four 14‐day cycles (five cigarettes/day).
Lukas Sigwart +2 more
wiley +1 more source

