Results 101 to 110 of about 23,176 (215)

Iloperidone treatment mitigates the Juvenile Huntington's Disease phenotype possibly via Sigma‐1 Receptor Modulation

The FEBS Journal, EarlyView.
We investigated the potential of iloperidone as an activator of Sigma‐1 receptor (S1R) neuroprotective function in juvenile Huntington's disease (jHD). We tested iloperidone on cortical neurons differentiated from patient‐derived iPSCs, demonstrating that it acts as a S1R agonist, decreasing apoptosis, huntingtin aggregation, and oxidative stress ...
Ersilia Fornetti, Gaia Galluzzi, Mario Frezzini, Cécile Exertier, Vittorio Brufani, Gianni Colotti, Giancarlo Ruocco, Jessica Rosati, Angelo Luigi Vescovi, Daniele Narzi, Ilaria Genovese, Andrea Ilari   +11 more
wiley   +1 more source

FORECASTOR. I. Finding Optics Requirements and Exposure Times for the Cosmological Advanced Survey Telescope for Optical and UV Research Mission

The Astronomical Journal
The Cosmological Advanced Survey Telescope for Optical and ultraviolet Research (CASTOR) is a proposed Canadian-led 1 m class space telescope that will carry out ultraviolet and blue optical wide-field imaging, spectroscopy, and photometry.
Isaac Cheng, Tyrone E. Woods, Patrick Côté, Jennifer Glover, Dhananjhay Bansal, Melissa Amenouche, Madeline A. Marshall, Laurie Amen, John Hutchings, Laura Ferrarese, Kim A. Venn, Michael Balogh, Simon Blouin, Ryan Cloutier, Nolan Dickson, Sarah Gallagher, Martin Hellmich, Vincent Hénault-Brunet, Viraja Khatu, Cameron Lawlor-Forsyth, Cameron Morgan, Harvey Richer, Marcin Sawicki, Robert Sorba   +23 more
doaj   +1 more source

The Photodetector Array Camera and Spectrometer (PACS) on the Herschel Space Observatory [PDF]

, 2010
The Photodetector Array Camera and Spectrometer (PACS) is one of the three science instruments on ESA's far infrared and submillimetre observatory. It employs two Ge:Ga photoconductor arrays (stressed and unstressed) with 16x25 pixels, each, and two ...
A. Contursi, A. Mazy, A. Poglitsch, Ade, Agnese, B. Ali, B. Altieri, B. Marquet, B. Vandenbussche, Billot, C. Cara, C. Jamar, C. Jean, C. Kiss, C. van Hoof, C. Waelkens, Cantalupo, D. Cesarsky, D. Lemke, D. Lutz, D. Schmitt, Duband, E. Callut, E. Doumayrou, E. Renotte, E. Sturm, E. Wieprecht, E. Wiezorrek, F. Kerschbaum, F. Montfort, Fischer, Fletcher, Fruchter, G. Jakob, G. Tofani, H. Bischof, H. Feuchtgruber, Huygen, Inguscio, J. Blommaert, J. Cepa, J. de Jong, J. Herreros, J. Martignac, J. Putzeys, J. Schreiber, J. Schubert, J. Stegmaier, J.-L. Augueres, J.-M. Gillis, K. Exter, K. Okumura, Katterloher, Kraft, Kraft, Krause, L. Barl, L. Duband, L. Morbidelli, L. Rodriguez, Looney, M. Benedettini, M. Inguscio, M. Nielbock, M. Sauvage, M. Thiel, M. Wetzstein, Merken, Müller, Müller, N. Belbachir, N. Billot, N. Geis, O. Boulade, O. H. Bauer, O. Krause, Ottensamer, P. Agnèse, P. Andreani, P. Merken, P. Popesso, P. Royer, P. Saraceno, Pilbratt, Poglitsch, Poglitsch, Poglitsch, Poglitsch, R. Cerulli, R. Genzel, R. Huygen, R. Katterloher, R. Orfei, R. Ottensamer, R. Vavrek, Renotte, S. Madden, S. Pezzuto, S. Regibo, Schreiber, Schulz, Shirahata, Simoens, Stegmaier, T. Henning, T. Müller, U. Grözinger, U. Klaas, V. Doublier, V. Reveret, W. De Meester, Wieprecht, Y. Creten, Z. Balog   +113 more
core   +2 more sources

30 Doradus - Ultraviolet and optical stellar photometry

The Astrophysical Journal, 1993
Ultraviolet Imaging Telescope (UIT) UV magnitudes in four bands, together with optical B magnitudes, are presented for up to 314 early-type stars located in a 9.7 x 9.7 arcmin field centered on R136. The magnitudes have an rms uncertainty estimated at 0.10 mag from a comparison between the UIT magnitudes and the IUE spectra.
Jesse K. Hill, Ralph C. Bohlin, Kwang-Ping Cheng, Michael N. Fanelli, Paul Hintzen, Robert W. O'Connell, Morton S. Roberts, Andrew M. Smith, Eric P. Smith, Theodore P. Stecher   +9 more
openaire   +1 more source

Long‐read sequencing‐based atlas of tissue‐specific expression of DNM1L transcript variants

The FEBS Journal, EarlyView.
Targeted long‐read sequencing resolves full‐length DNM1L (Drp1) isoforms and reveals conserved, tissue‐specific expression patterns across human and mouse tissues. Functional assays show that Drp1 isoforms differ in their ability to drive mitochondrial fission, independent of abundance, with specific exons modulating activity.
Feng Yan, Jafar S. Jabbari, Naomi X. L. Ling, Anne M. Kong, Jia Q. Truong, Marnie L. Maddock, Ayeshah A. Rosdah, Christopher G. Langendorf, Lifang Zhang, Jarmon G. Lees, Sebastian Bass‐Stringer, Danise Ann Onda, Alice Pébay, Mirella Dottori, Kim Loh, Jessica K. Holien, Sean Lal, Nadia M. Davidson, Jonathan S. Oakhill, Shiang Y. Lim   +19 more
wiley   +1 more source

Keck and Hubble Observations Show that MOA-2008-BLG-379Lb is a Super-Jupiter Orbiting an M Dwarf

The Astronomical Journal
We present high angular resolution imaging that detects the MOA-2008-BLG-379L exoplanet host star using Keck adaptive optics and the Hubble Space Telescope.
David P. Bennett, Aparna Bhattacharya, Jean-Philippe Beaulieu, Naoki Koshimoto, Joshua W. Blackman, Ian A. Bond, Clément Ranc, Natalia Rektsini, Sean K. Terry, Aikaterini Vandorou, Jessica R. Lu, Jean Baptiste Marquette, Greg Olmschenk, Daisuke Suzuki   +13 more
doaj   +1 more source

The Asymptotic Giant Branch and the Tip of the Red Giant Branch as Probes of Star Formation History: The Nearby Dwarf Irregular Galaxy KKH 98 [PDF]

, 2010
We investigate the utility of the asymptotic giant branch (AGB) and the red giant branch (RGB) as probes of the star formation history (SFH) of the nearby (D=2.5 Mpc) dwarf irregular galaxy, KKH 98.
Ammons, S. M., Dalcanton, J., Dolphin, A., Girardi, Leo, Koo, D. C., Max, C., Melbourne, J., Williams, B.   +7 more
core   +2 more sources

The hidden science of haptics: A pedagogical review of tactile evaluation in cosmetics

International Journal of Cosmetic Science, EarlyView.
This review explores the physiological basis of tactile perception and critically examines classical and emerging sensory methods used in cosmetics, advocating for broader methodological integration and recognition of sensory analysis in the field. Abstract Sensory analysis is a cornerstone of cosmetic development, yet remains underrepresented in peer ...
Morgane Postec, Daria Terescenco, Ecaterina Gore   +2 more
wiley   +1 more source

Probing Disk Ice Content and Polycyclic Aromatic Hydrocarbon Emission through Multiband MagAO+Clio Images of HD 141569

The Astrophysical Journal
We present resolved images of the inner disk component around HD 141569A using the Magellan adaptive optics system with the Clio2 1–5 μ m camera, offering a glimpse of a complex system thought to be in a short evolutionary phase between protoplanetary ...
Jay K. Kueny, Alycia J. Weinberger, Jared R. Males, Katie M. Morzinski, Laird M. Close, Katherine B. Follette, Philip M. Hinz   +6 more
doaj   +1 more source

Data-calibrated point spread function prediction

Astronomy & Astrophysics
Context. Precise knowledge of the point spread function (PSF) underpins many data analysis steps in astronomy, from photometry and astrometry to source de-blending and deconvolution.
Kuznetsov Arseniy, Neichel Benoit, Oberti Sylvain, Fusco Thierry   +3 more
doaj   +1 more source