Results 41 to 50 of about 22,843 (189)

A novel image reconstruction method applied to deep Hubble Space Telescope Images [PDF]

, 1997
We have developed a method for the linear reconstruction of an image from undersampled, dithered data, which has been used to create the distributed, combined Hubble Deep Field images -- the deepest optical images yet taken of the universe. The algorithm,
Fruchter, Andrew, Hook, Richard
core   +3 more sources

Estrogen Alleviates Sevoflurane‐Induced Neurotoxicity by Inhibiting ERα‐Tau Binding

Advanced Science, EarlyView.
Sevoflurane‐induced neurotoxicity exhibits sex differences, and estrogen can mitigate these effects; however, its protective action appears to be time‐window dependent, which may be related to the competitive binding of estrogen and Tau to ERα. Abstract Sevoflurane‐induced neurotoxicity is age‐dependent, but the role of sex differences is unclear ...
Feixiang Li, Bingqing Gong, Zichen Song, Nuo Yang, Yuming Liu, Jinqin Zhang, Dujuan Li, Yongyan Yang, Yonghao Yu   +8 more
wiley   +1 more source

MCAO near-IR photometry of the Globular Cluster NGC 6388: MAD observations in crowded fields

, 2008
Deep photometry of crowded fields, such as Galactic Globular Clusters, is severely limited by the actual resolution of ground-based telescopes. On the other hand, the Hubble Space Telescope does not provide the near-infrared (NIR) filters needed to allow
A. Baruffolo, A. Moretti, A. P. Milone, A. Sarajedini, Anderson, Anderson, Arcidiacono, Ashman, Bedin, Bedin, Busso, C. Arcidiacono, Caloi, Carretta, Cassisi, Catelan, D'Antona, D'Antona, De Angeli, E. Diolaiti, E. Marchetti, G. Piotto, Girardi, Gratton, Gullieuszik, Harris, Hawarden, Hughes, J. Anderson, J. Farinato, J. Kolb, L. R. Bedin, Lee, M. Lombini, Marchetti, Milone, Pancino, Penny, Pietrinferni, Piotto, Piotto, R. Brast, R. Donaldson, R. Falomo, R. Ragazzoni, Ragazzoni, Ragazzoni, Ragazzoni, Raimondo, Rich, Rich, S. Tordo, Salaris, Sarajedini, Schlegel, Sirianni, Stetson, Valenti, Yoon   +58 more
core   +2 more sources

cGAS Inhibits ALDH2 to Suppress Lipid Droplet Function and Regulate MASLD Progression

Advanced Science, EarlyView.
cGAS is a cytosolic DNA sensor known for innate immune defense. cGAS binds and suppresses ALDH2 are showed, limiting acetyl‐CoA production. cGAS loss activates ALDH2, promoting histone acetylation, lipogenesis, and lipid droplets accumulation. cGas‐/‐ mice on a high‐fat diet show signs of worsened MASLD.
Ying Wang, Yu Deng, Jianfeng Chen, Quentin Hahn, David S. Umbaugh, Zhigang Zhang, Yanqiong Zhang, Sarah E. Rowe, Lupeng Li, Laura E. Herring, Brian P. Conlon, Edward A. Miao, Blossom Damania, Anna Mae Diehl, Pengda Liu   +14 more
wiley   +1 more source

The orbit of the brown dwarf binary Gl 569B [PDF]

, 2001
We present photometric, astrometric and spectroscopic observations of the nearby (9.8 pc) low-mass binary Gl 569Bab (in turn being a companion to the early-M star Gl 569A), made with the Keck adaptive optics facility.
B. F. Lane, Baraffe I., Bessell M. S., Bruhweiler F., Casali M. M., Delfosse X., E. L. Martin, Festin L., Grossman A. S., Heintz W. D., Huensch M., Jones H. R. A., Jones H. R. A., M. C. Britton, M. R. Zapatero Osorio, Pallavicini R., Perryman M. A. C., S. R. Kulkarni   +17 more
core   +2 more sources

Synaptic Dysfunction in the Anterior Cingulate Cortex Underlies Pain‐Anxiety Comorbidity in a Mandibular Asymmetry Mouse Model

Advanced Science, EarlyView.
This study establishes a mandibular asymmetry (MA) mouse model that recapitulates chronic orofacial pain and anxiety comorbidity. Anterior cingulate cortex (ACC) hyperactivation and synaptic dysfunction are identified as central neural mechanisms underlying these pathologies, with chemogenetic inhibition of ACC CaMKII+ neurons effectively reversing ...
Zhaoyichun Zhang, Yanran Zhang, Jialin Si, Honghui Mao, Feng He, Jin Ning, Guaiguai Ma, Xiaohua Chen, Haoxiang Xiao, Yuanyuan Zhu, Haifeng Zhang, Yifan Lu, Qian Liu, Meng Nian, Shiquan Sun, Shibin Yu, Shengxi Wu, Ze Fan, Zuolin Jin, Jing Huang   +19 more
wiley   +1 more source

Ex vivo liquid core fiber photometry with high-resolution 3D printing

Sensors and Actuators Reports
High resolution 3D printing emerges as an alternative to microfabrication due to its fine resolution along with one-step manufacturing. Thus, it is broadly used in many fields, such as biological and chemical applications.
Yu Chang, Can Wang, Ke Du
doaj   +1 more source

SFADI: the Speckle-Free Angular Differential Imaging method [PDF]

, 2017
We present a new processing technique aimed at significantly improving the angular differential imaging method (ADI) in the context of high-contrast imaging of faint objects nearby bright stars in observations obtained with extreme adaptive optics (EXAO)
Antoniucci, Simone, Causi, Gianluca Li, Mattioli, Massimiliano, Pedichini, Fernando, Stangalini, Marco, Testa, Vincenzo   +5 more
core   +2 more sources

Astrocytic PERK Deficiency Drives Prefrontal Circuit Dysfunction and Depressive‐Like Behaviors

Advanced Science, EarlyView.
Chen et al. show that the endoplasmic reticulum (ER) stress sensor PERK is downregulated in prefrontal cortex (PFC) astrocytes in major depressive disorder and in chronic‐stress mouse models. In young mice, astrocyte‐specific PERK loss reduces the synaptogenic cue thrombospondin‐1 (TSP1), leading to synaptic and circuit deficits and depressive‐like ...
Kai Chen, Riya Gupta, Yosuke M. Morizawa, Yu Qin, Xingyu Du, Cynthia Pang, Osama Al‐Dalahmah, Maura B. Dupont, Guang Yang   +8 more
wiley   +1 more source

New Astronomical Observatory Design for the Detection and Tracking of Satellite Objects: The Satellite Robotic Observatory (SRO)

Remote Sensing
Robotic Astronomical Observatories (RAOs) have provided very good results in different research projects in astrophysics/astronomy. Their applications in the detection, tracking, and identification of near-Earth objects have contributed to the ...
Francisco Espartero, Javier Cubas, David Nespral, Santiago Pindado   +3 more
doaj   +1 more source