Results 61 to 70 of about 337,219 (230)

Hederagenin Attenuates Morphine Addiction via GABAA1‐Mediated Modulation of Ca2+–CaMK–CREB Signaling in Ventral Tegmental Dopaminergic Neurons

Advanced Science, EarlyView.
Hederagenin is identified as a GABAA1‐targeting natural compound that suppresses morphine‐associated reward by restraining Ca2+–CaMK–cAMP–CREB signaling in ventral tegmental dopaminergic neurons. RVG29‐modified liposomal delivery further enhances brain accumulation and behavioral efficacy, providing a mechanistically defined strategy for natural ...
Hongyang Jiang, Ziting Zhou, Nannan Xue, Jiasi Deng, Yuanyuan Zhou, Xinying Lv, Yuxuan Wang, Yi Zhang, Haotian Pan, Geyan Xu, Yinkun Tao, Mengran Li, Xin Cui, Hongyue Ma, Qian Wang, Zhigang Lu   +15 more
wiley   +1 more source

Array Polarimetry and Optical-Differencing Photometry [PDF]

Symposium - International Astronomical Union, 1995
Array detectors have improved the efficiency of optical polarimetry sufficiently for this technique to become part of the standard arsenal of observational facilities. However, we could gain even more: spatially-differentiating photometry can be implemented as an option of array Polarimeters and low-noise, high-frame-rate array detectors will allow ...
openaire   +1 more source

The Calibration of theSwiftUVOT Optical Observations: A Recipe for Photometry [PDF]

Publications of the Astronomical Society of the Pacific, 2006
Accepted for publication in PASP (2006 Jan issue). Significantly improved version with many more standard stars.
Li, W, Jha, S, Filippenko, AV, Bloom, JS, Pooley, D, Foley, RJ, Perley, DA   +6 more
openaire   +3 more sources

SaNDi-SHoP: Searching for Satellites’N’Disks with a Star-Hopping Program

Astronomy & Astrophysics
Context. Over the past decade, advances in high-contrast imaging instrumentation, coupled with extreme adaptive optics systems, have enabled the discovery of tens of planets and brown dwarfs orbiting at wide separations from their host stars (a ≳ 10 au).
Bernardi A., Zurlo A., Lazzoni C., Desidera S., Mesa D., Pérez S., Nogueira P. H., Barbato D., Dasgupta A.   +8 more
doaj   +1 more source

A Gut‐Brain Axis Underlying Succinate‐Associated Compulsive‐Like Behavior

Advanced Science, EarlyView.
Gut‐derived succinate is associated with an excitatory‐inhibitory imbalance in dmPFC glutamatergic neurons, involving microglial SUCNR1 activation and vagal afferent signaling via upregulated gut 5‐HT4 receptors along the DVC‐CeA‐dmPFC circuit, changes that are linked to excessive compulsive‐like behavior.
Yi Li, Ying‐Dan Zhang, Wei Wang, Xin‐Yi Wu, Di Li, Xin Gong, Fei Tian, Meng‐Yu Dai, Jian Gao, Zi‐Feng Zheng, Zi‐Yang Bi, Dong‐Dong Shi, Zhen Wang   +12 more
wiley   +1 more source

A Molecularly Defined Midbrain Circuit Mechanism for Sound‐Driven Defensive Behavior and Anxiety

Advanced Science, EarlyView.
Schematic diagram showing the Cbln2+ ICx–dPAG circuit for sound‐driven defensive and anxiety‐like behaviors. ABSTRACT The innate defense behaviors in response to threatening sounds play a fundamental role in survival. However, the neural circuits that detect threat‐relevant auditory cues and transform them into defensive behaviors remain poorly defined.
Jie Cao, Xingxing Lai, Lifang Huo, Zhouyuan Zheng, Qian Zhang, Zhimin Ye, Panpan Wan, Chao Ma, Congping Shang   +8 more
wiley   +1 more source

Optical Photometry of the GRB 010222 Afterglow

, 2001
The optical afterglow of GRB 010222 was observed using the recently installed 2-m telescope at the Indian Astronomical Observatory, Hanle, and the telescopes at the Vainu Bappu Observatory, Kavalur, beginning ~ 0.6 day after the detection of the event.
Cowsik, R., Prabhu, T. P., Anupama, G. C., Bhatt, B. C., Sahu, D. K., Ambika, S., Padmakar, Bhargavi, S. G.   +7 more
openaire   +2 more sources

Long-Term Optical Photometry of the Dwarf Nova VW HYI [PDF]

International Astronomical Union Colloquium, 1987
AbstractLong-term five-colour photometry of the dwarf nova VW Hyi shows no evidence for a secular change of the flux during the quiescent interval between normal outbursts (3σ upper limits between 0.16 and 0.20 mag in the five passbands). However, the amplitudes in the orbital B-U and U-W colour curves change during quiescence.
S. F. Van Amerongen, J. Van Paradijs
openaire   +1 more source

Image sharpening metrics and search strategies for indirect adaptive optics [PDF]

, 2000
Adaptive optics is concerned with the correction of turbulence induced aberrations and mis-alignments in optical systems. It is an expensive and complicated technology which has been developed for astronomy and defence applications.
Doble, N., Doble, Nathan
core  

Flickers, Bursts, and Dips: Detecting Rapid Variability with the g(2) Autocorrelation Function

The Astrophysical Journal
Rapid optical transient events can be hard to detect because of the limited number of photons they produce. I discuss a method of inferring the presence of fast, chaotic variability in photometry using the normalized autocorrelation function, what is ...
Brian C. Lacki
doaj   +1 more source