Results 71 to 80 of about 11,034 (258)

A Universal Protein Ladder for Standardization of Diverse FRET Assays

Advanced Science, EarlyView.
Translating FRET measurements from in vitro to intracellular environments requires universal benchmarks. We present a modular protein ladder using TPR motifs to harmonize data across diverse platforms. This predictable calibration curve bridges single molecule FRET measurements, with cell based measurements including FLIM‐FRET.
Evelyn R. Smith, Katie L. Gelder, Lewis Hunter‐Craig, Daniel A. Bose, Timothy D. Craggs, Alison E. Twelvetrees   +5 more
wiley   +1 more source

Low-dose high-resolution chest CT in adults with cystic fibrosis: intraindividual comparison between photon-counting and energy-integrating detector CT

European Radiology Experimental
Background Regular disease monitoring with low-dose high-resolution (LD-HR) computed tomography (CT) scans is necessary for the clinical management of people with cystic fibrosis (pwCF).
Marko Frings, Matthias Welsner, Christin Mousa, Sebastian Zensen, Luca Salhöfer, Mathias Meetschen, Nikolas Beck, Denise Bos, Dirk Westhölter, Johannes Wienker, Christian Taube, Lale Umutlu, Benedikt M. Schaarschmidt, Michael Forsting, Johannes Haubold, Sivagurunathan Sutharsan, Marcel Opitz   +16 more
doaj   +1 more source

Nanovesicles With Mechanically Induced Adjuvanticity for Robust Melanoma Vaccination Toward Tumor‐Associated Macrophages

Advanced Science, EarlyView.
Rigidity‐tunable nanovesicle (P‐Pm) with mechanically induced adjuvanticity toward tumor‐associated macrophages (TAMs) was designed to engineer R848/gp100 antigen ‐loaded nanovaccine (P@Rg‐Pm), which achieved outstanding anti‐tumor outcomes in both therapeutic and preventive model of B16‐F10 melanoma.
Bangyue Luo, Liyan Qiu
wiley   +1 more source

Improvement of chest low-dose CT image quality with photon counting detector CT

Zhongguo linchuang yanjiu
Objective To compare the image quality of photon-counting detector CT (PCD-CT) images with that of conventional energy-integrating detector CT (EID-CT) images in chest low-dose CT (LDCT) imaging, and to investigate whether PCD-CT can achieve better ...
YUAN Yong, CHEN Jiliang, LUO Song, HUANG Ling   +3 more
doaj   +1 more source

Dual Lineages of Langerhans Cells Cooperate to Restore the Immune Barrier after Skin Injury

Advanced Science, EarlyView.
After skin injury, the epidermal immune barrier is rebuilt by two sources of Langerhans cells. Resident Langerhans cells first move into the wound during re‐epithelialization, guided by CXCR2 signaling. Later, recruited monocytes become long‐lived Langerhans cells.
Axel D. Schmitter‐Sánchez, Nicholas Basista, Sudhanshu Mishra, Hyeri Kim, Audrey Bench, Catherine Matte‐Martone, Min‐Soo Seo, Gun Woo Lee, Sangbum Park   +8 more
wiley   +1 more source

Evaluation of an Analytic Reconstruction Method as a Platform for Spectral Cone-Beam CT

IEEE Access, 2018
With the fast development of photon counting detection techniques, spectral computed tomography (CT) with a photon counting detector has attracted considerable attention by increasing energy resolution to identify and discriminate materials.
Huihua Kong, Rui Liu, Jinxiao Pan, Hengyong Yu   +3 more
doaj   +1 more source

Nanometer Layer Coating to Lactose Particles for Optimization of Dexamethasone Pulmonary Delivery

Advanced Science, EarlyView.
Nanometer layer coating (NLC) was investigated and its mechanism illustrated by advanced characterization techniques. The effects and application for the inhalation of dexamethasone (DEX) were demonstrated through in vitro and in vivo evaluation. This approach increased DEX bioavailability and enabled the dose to be reduced to 1/30 of the intravenous ...
Qin Nie, Jiahe Liu, Xiangyu Zhao, Siying Yang, Han Sun, Bingqian Jia, Xiaohong Ren, Xintao Chen, Lixin Sun, Li Wu, Caifen Wang, Jiwen Zhang   +11 more
wiley   +1 more source

Advancing Aortic Dissection Imaging: First Clinical Experience of Photon-Counting CT with Ultra-Fast Spectral Imaging

Diagnostics
Background: Computed tomography (CT) is the standard of reference for diagnosis and follow-up in aortic dissection (AD). Localizing the entry and identifying false and true lumen are as important as differing post-treatment changes from contrast media ...
Daniel Dillinger, Maria Weiss, Hanns L. Kaatsch, Christian Bauer, Achim Hagen, Matthias F. Froelich, Stephan Waldeck, Daniel Overhoff   +7 more
doaj   +1 more source

Engineering Ultrastable Intrinsic Radicals: Graphene Quantum Dots With NIR‐II Emission for Dynamic Deep‐Tissue Bioimaging

Advanced Science, EarlyView.
Stable radicals are attractive for photonic and quantum information technologies but are often limited by instability. We stabilize intrinsic radicals in graphene quantum dots via 2D polymerization of perylene derivatives, where bilayer defect confinement suppresses quenching (100–500 K).
Qin Xu, Yijie Hou, Bingzhe Wang, Tesen Zhang, Yupeng Liu, Shuaiqi Li, Maohua Chen, Guichuan Xing, Dongbo Guo, Songnan Qu   +9 more
wiley   +1 more source

Ultra-high spatial resolution at photon-counting computed tomography: technical insights and sustainable applications in cardiothoracic imaging

European Radiology Experimental
The latest technological advancements in CT enable the exploration of unprecedented limits of spatial resolution in in vivo imaging. Nowadays, ultra-high-resolution imaging is available by using CT with detector elements at or smaller than 0.25 mm along ...
Mariaelena Occhipinti, Alberto Clemente, Carmelo De Gori, Vincenzo Positano, Danilo Neglia, Simona Celi, Antonella Meloni, Sergio Berti, Filippo Cademartiri   +8 more
doaj   +1 more source