Extracorporeal photopheresis as induction therapy in lung transplantation for cystic fibrosis: a pilot randomized trial [PDF]
IntroductionExtracorporeal photopheresis (ECP) is a viable treatment that slows the progression of chronic lung allograft dysfunction. Despite its immunoregulatory potential, data on extracorporeal photopheresis as an induction therapy remain rather ...
Ilaria Righi +19 more
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Is a Functional Cure Possible in Autoimmune Diseases? Evidence from Trigger Eradication, Transplantation, and Cellular Therapies [PDF]
Introduction Traditionally considered incurable, autoimmune diseases (AIDs) may—in specific circumstances—achieve sustained remission or even a “functional cure,” defined as durable clinical and laboratory remission without immunosuppression. This review
Jozélio Freire de Carvalho +1 more
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Extracorporeal Photopheresis—An Overview
Extracorporeal photopheresis (ECP) has been in clinical use for over three decades after receiving FDA approval for the palliative treatment of the Sézary Syndrome variant of cutaneous T-cell lymphoma (CTCL) in 1988.
Ara Cho +2 more
doaj +3 more sources
Extracorporeal Photopheresis Stimulates Tissue Repair after Transplantation [PDF]
Extracorporeal photopheresis (ECP) is a safe and effective therapy with long-established indications in treating T cell–mediated immune diseases, including steroid refractory graft-versus-host disease and chronic rejection after heart or lung ...
Fabiola Arella, MSc +2 more
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Extracorporeal photopheresis as a therapeutic approach for treatment resistant immune-related adverse events in anti-PD-1-treated melanoma patients [PDF]
BackgroundCheckpoint inhibition induced immune-related adverse events (irAE) may be steroid-dependent or steroid-refractory and are associated with increased morbidity, mortality and potentially compromised anti-tumor immunity.
Carl Maximilian Thielmann +23 more
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Lower incidence of chronic graft-versus-host disease after ruxolitinib plus extracorporeal photopheresis versus ruxolitinib alone in steroid-refractory acute graft-versus-host disease following allogeneic stem cell transplantation [PDF]
We compared long-term outcomes in 78 patients with steroid-refractory acute graft-versushost disease (SR-aGVHD) treated at the University Medical Center Hamburg, Germany between December 2015 and August 2022 who received either ruxolitinib alone (Ruxo ...
Iryna Lastovytska +14 more
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Use of Extracorporeal Photopheresis Treatment Over Time (2001–2023) in Alberta, Canada: A Retrospective Cohort Study [PDF]
Louis Girard +7 more
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Have no fear, IR is here: A case of right brachiocephalic vein /svc recanalization for port placement [PDF]
A patient with a history of cystic fibrosis and bilateral lung transplant presented internal jugular port placement for extracorporeal photopheresis in the setting of acute rejection.
Garrett DePalma, DO, Tomas Mujo, DO
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Extracorporeal photopheresis is an established procedure for refractory graft-versus-host disease, a major complication associated with notable morbidity and mortality in patients with allogeneic hematopoietic stem cell transplant.
Adriana Sassone +4 more
doaj +1 more source
Extracorporeal photopheresis (ECP), an immunomodulatory therapy for the treatment of chronic graft-versus-host disease (cGvHD), exposes isolated white blood cells to photoactivatable 8-methoxypsoralen (8-MOP) and UVA light to induce the apoptosis of T ...
Eidi Christensen +7 more
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