Exploring the Role of Extracorporeal Photopheresis in Kidney Transplant Management. [PDF]
Transplant DirectExtracorporeal photopheresis (ECP) is emerging as an apoptotic cell-based therapy that suppresses alloimmunity, promotes donor-specific regulation, and reduces the need for conventional maintenance immunosuppression.
Nicoli M, Rovira J, Diekmann F.
europepmc +3 more sources
Lower incidence of chronic graft-versus-host disease after ruxolitinib plus extracorporeal photopheresis versus ruxolitinib alone in steroid-refractory acute graft-versus-host disease following allogeneic stem cell transplantation [PDF]
HaematologicaWe compared long-term outcomes in 78 patients with steroid-refractory acute graft-versushost disease (SR-aGVHD) treated at the University Medical Center Hamburg, Germany between December 2015 and August 2022 who received either ruxolitinib alone (Ruxo ...
Iryna Lastovytska +14 more
doaj +3 more sources
Extracorporeal Photopheresis Stimulates Tissue Repair after Transplantation [PDF]
Transplantation DirectExtracorporeal photopheresis (ECP) is a safe and effective therapy with long-established indications in treating T cell–mediated immune diseases, including steroid refractory graft-versus-host disease and chronic rejection after heart or lung ...
Fabiola Arella, MSc +2 more
doaj +3 more sources
Successful prevention of BK-polyomavirus nephropathy using extracorporeal photopheresis for immunosuppression minimisation following severe BK polyomavirus replication after kidney transplantation in a double lung transplant recipient, a case report [PDF]
BMC NephrologyBackground BK-polyomavirus (BKpyV) nephropathy (BKVN) is associated with end-stage kidney disease in kidney and non-kidney solid organ transplantation, with no curative treatment.
Florent Von Tokarski +12 more
doaj +3 more sources
Extracorporeal Photopheresis in Lung Transplantation: Present Applications and Emerging Research. [PDF]
Transplant DirectExtracorporeal photopheresis (ECP) is an immunomodulatory therapy currently used as an add-on treatment for the prevention and management of organ rejection in lung transplantation.
Alemanno S, Jaksch P, Benazzo A.
europepmc +2 more sources
Transplantation DirectBackground. The benefit of extracorporeal photopheresis on the course of kidney transplant rejection is unknown. The aim of our study was to investigate the variations in transcriptomics on graft biopsies when extracorporeal photopheresis was used to ...
Arnaud Lionet, MD +9 more
doaj +2 more sources
Potential Impact of Extracorporeal Photopheresis on Trained Immunity and Organ Transplant Acceptance. [PDF]
Transplant DirectExtracorporeal photopheresis (ECP) is a well-established, safe, and effective immunomodulatory therapy currently used in clinics to decrease T cell–mediated immunity in various disorders, including autoimmune diseases and chronic rejection in organ ...
Tocco C, Ochando J.
europepmc +2 more sources
Extracorporeal Photopheresis: Does It Have a Potential Place Among Cell-based Therapies? [PDF]
Transplant DirectExtracorporeal photopheresis (ECP) is a therapeutic intervention for modulating immune responses using an autologous apoptotic cell-based product, known as a photopheresate.
Parsonidis P, Wekerle T.
europepmc +2 more sources
Extracorporeal photopheresis in acute and chronic steroid‑refractory graft-versus-host disease: an evolving treatment landscape [PDF]
Leukemia, 2022 Patients with steroid-refractory graft-versus-host disease (GvHD) are known to have a poor prognosis and for decades no approved drug has been available to treat this serious condition.
H. Greinix, F. Ayuk, R. Zeiser
semanticscholar +2 more sources
Extracorporeal photopheresis for the prevention of rejection after lung transplantation: a prospective randomised controlled trial. [PDF]
Eur Respir JBackground Lung transplant recipients have the worst long-term outcomes of all solid organs due to acute rejection and chronic lung allograft dysfunction (CLAD).
Benazzo A +15 more
europepmc +2 more sources