Results 251 to 260 of about 8,151 (283)

Extracorporeal photopheresis: a review

Blood Reviews, 2001
Extracorporeal phototherapy (ECP) is a therapeutic approach based on the biological effect of psoralen 8-methoxypsoralen (8-MOP) and ultraviolet light A (UVA) on mononuclear cells collected by apheresis, and reinfused into the patient. Photopheresis is widely used for the treatment of patients with advanced cutaneous T-cell lymphoma (CTLC).
A, Oliven, Y, Shechter
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Extracorporeal Photopheresis as a Treatment Option for Immune-Related Adverse Events: Two Case Reports and a Prospective Study

Journal of immunotherapy
The wide use of immune checkpoint inhibitors has increased the frequency of immune-related adverse events (irAEs). While many are managed with corticosteroids or hormone substitution, up to 14.9% of irAEs are steroid-refractory or steroid-dependent and ...
T. Ruf, Farnaz Rahimi, D. Anz, Amanda Tufman, Suzanna Salzer, S. Zierold, D. Tomsitz, L. E. French, L. Heinzerling   +8 more
semanticscholar   +1 more source

Photopheresis; the risk of photoallergy

Journal of Photochemistry and Photobiology B: Biology, 1996
Photopheresis is a therapy for several T-cell-mediated disorders, aiming at a specific immune response against the pathogenic clone of T cells involved. With photopheresis, a mixture of patients' buffy coat and plasma, which contains 8-methoxypsoralen (8-MOP), is diluted with phosphate-buffered saline (PBS) and exposed to ultraviolet A radiation (UVA).
H P, van Iperen, G M, Beijersbergen van Henegouwen   +1 more
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[Extracorporeal photopheresis].

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1995
Extracorporeal photopheresis is a new therapeutic approach developed by Edelson et al.; it is conceptually designed for the management of diseases mediated by malignant lymphocyte pathology, such as cutaneous T-cell-lymphoma (CTCL), and other disorders mediated by aberrant lymphocyte function, e.g. autoimmune diseases.
B, Prinz, G, Plewig
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Extracorporeal photopheresis technical aspects

Transfusion and Apheresis Science, 2003
Extracorporeal photochemotherapy is a monotherapy first developed by Edelson et al. in 1987. It is a therapy in which 8-methoxypsoralen (8-MOP) containing lymphocytes are exposed to a long wavelength ultraviolet radiation (UVA) in an extracorporeal system.
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Extracorporeal Photopheresis After Heart Transplantation

Immunotherapy, 2014
The addition of extracorporeal photopheresis (ECP) to a standard immunosuppressive drug therapy after heart transplantation in clinical studies has shown to be beneficial, for example, by reducing acute rejection, allograft vasculopathy or CMV infection.
Markus J, Barten, Maja-Theresa, Dieterlen   +1 more
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Retinal Toxic Reactions Following Photopheresis

Archives of Dermatology, 2007
Extracorporeal photochemotherapy (ECP), also known as photopheresis, is a generally well-tolerated therapeutic, immunomodulatory approach successfully used in cutaneous T-cell lymphoma and other diseases produced by T-lymphocytes such as graft vs host disease.On 2 separate occasions, a 54-year-old white man with Sézary syndrome developed cutaneous ...
Jose Manuel, Vagace, Guillermo, Gervasini, Fernando, Morais, Julio, Benitez, Nieves, Alonso, Diego, de Argila, Isabel, Arranz, Roberto, Bajo   +7 more
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PHOTOPHERESIS AND AUTOIMMUNE DISEASES

Rheumatic Disease Clinics of North America, 2000
Although several case reports and case series suggest efficacy for photopheresis in the treatment of autoimmune diseases, few controlled studies have been conducted to test this hypothesis. After a decade of interest, multiple case reports, open trials, and one controlled study, the role of photopheresis in autoimmune disease remains to be established.
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Immunomodulation in Transplantation with Photopheresis

Artificial Organs, 1996
Abstract: Photopheresis is a technique in which peripheral blood mononuclear cells, in the presence of a photoacti‐vatable compound, are exposed extracorporeally to ultraviolet A light and reinfused, inducing a host autoregula‐tory immune response. Experimental work and ongoing clinical studies are helping to define the role of this novel, safe, and ...
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Extracorporeal Photopheresis

2012
Extracorporeal photopheresis (ECP) is the first FDA approved cellular photoimmunotherapy for cancer and has demonstrated efficacy in T-cell mediated disorders including prevention and treatment of acute and chronic graft-versus-host disease, organ transplant rejection, scleroderma, Crohn s disease and diabetes mellitus.
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