Results 71 to 80 of about 8,151 (283)

Extracorporeal Photopheresis in Dermatology

Actas Dermo-Sifiliográficas (English Edition), 2009
Extracorporeal photochemotherapy or photopheresis is an immunomodulatory therapy that combines leukapheresis with phototherapy. Blood from the patient is processed to give a leukocyte-rich plasma, which is then treated ex vivo with a photosensitizer and ultraviolet A radiation before reinfusion back into the patient.
L, Pérez-Carmona, A, Harto-Castaño, E, Díez-Recio, P, Jaén-Olasolo   +3 more
openaire   +2 more sources

scRNA‐Seq reveals anti‐lymphoma immune responses in mogamulizumab‐associated skin eruptions

Journal of the European Academy of Dermatology and Venereology, EarlyView.
CCR4 was expressed in malignant clones and regulatory T cells in untreated CTCL, that were decreased in MAR. Malignant clones in MAR showed a silenced phenotype with decreases in central memory markers SELL and CCR7, and GTP‐binding member GIMAP7 and upregulation of MMP2 inhibitor TIMP2 and tumour suppressor gene RUNX3.
Shannon Meledathu, Agata Kurowski, Malini P. Naidu, Jonas Adalsteinsson, Shane A. Meehan, Natalia Alkon, Lauren R. Port, Sumanth Chennareddy, Emry R. Cohenour, Grace Christensen, Jonah Shulman, Nicholas Gulati, Constanze Jonak, Patrick M. Brunner   +13 more
wiley   +1 more source

Chart review study of real-world clinical outcomes in patients with cutaneous T-cell lymphoma treated with extracorporeal photopheresis in the US in 2017–2019

Journal of Dermatological Treatment
Background Response rates of approved systemic therapies for cutaneous T-cell lymphoma (CTCL) hover near 30%, suggesting unmet need. This study describes real-world treatment patterns and response rates of extracorporeal photopheresis (ECP) in CTCL ...
Michael Girardi, Kacie Carlson, Xingyue Huang, Shelby L. Corman, Patrick Edmundson, Jordana Schmier, Hrishikesh P. Kale, Rutika Raina, Francine Foss   +8 more
doaj   +1 more source

Not all intravenous immunoglobulin preparations are equally well tolerated [PDF]

, 2010
Intravenous immunoglobulin (IVIG) is used for many indications beyond the original substitution in primary antibody deficiency. Whereas many reports mention adverse reactions, no comparative data exist concerning the incidence of side-effects among the ...
Benden, C, Boehler, A, Feldmeyer, L, French, L E, Haile, S R, Hofbauer, F G L, Speich, R   +6 more
core   +1 more source

Extracorporeal photopheresis: how, why and for whom?

Pediatric Hematology/Oncology and Immunopathology, 2023
   Extracorporeal photopheresis is a method of cell therapy that was developed and introduced into clinical practice of various specialties over 30 years ago but its mechanism of action, clinical application and the possibility of further modification ...
I. Kumukova, P. Trakhtman, E. Kurnikova
semanticscholar   +1 more source

Apoptosis kinetics of purified and PBMC‐associated lymphocytes after photopheresis‐like 8‐methoxypsolaren/UVA treatment

Photochemistry and Photobiology, EarlyView.
Extracorporeal photopheresis (ECP) induces apoptosis in circulating immune cells, but its kinetics vary slightly depending on the cell type. We compared the progression of apoptosis in PBMCs versus highly purified T cells exposed to 8‐methoxypsoralen and ultraviolet A.
Carlos Agustin Villegas‐Valverde, Imilla Casado Hernandez, Yandy Marx Castillo‐Aleman, Gisela Maria Suarez‐Formigo, Amar Riaz, Antonio Alfonso Bencomo‐Hernandez, Yendry Ventura‐Carmenate   +6 more
wiley   +1 more source

Extracorporeal photopheresis—New insights into an old procedure

Transfusion Medicine, EarlyView.
Abstract Background Extracorporeal photopheresis (ECP) is a safe immunomodulatory strategy that induces cell‐type selective apoptosis through photodynamic processes. Despite decades of use, the mechanisms underlying ECP remain largely unexplored, particularly in studies examining specific immune cell subsets in ex vivo setups.
Sabine Seiffert, Janine Kirchberg, Enrica Bach, Victoria Menger, Mandy Brückner, Ulrich Sack, Ulrike Köhl, Uwe Platzbecker, Andreas Boldt, Marco Herling, Vladan Vučinić   +10 more
wiley   +1 more source

Eccrine poromatosis following chemotherapy and radiation therapy [PDF]

, 2019
Eccrine poroma presents as a single, symptomless erythematous papule in areas with a high density of eccrine sweat glands. Although rare, eccrine poromas can present as multiple lesions, otherwise known as eccrine poromatosis.
Chiu, Melvin, Kim, Gene, Nguyen, Khoa
core  

A European Multi-Center Analysis of Extracorporeal Photopheresis as Therapy for Chronic Lung Allograft Dysfunction

Transplant International
Extracorporeal photopheresis (ECP) is used by few lung transplant centers to treat chronic lung allograft dysfunction (CLAD). Although reported results suggest a beneficial effect on CLAD progression, evidence is limited to single center experiences. The
A. Benazzo, C. Bagnera, F. Ius, C. Del Fante, J. Gottlieb, K. Hoetzenecker, Federica Meloni, P. Jaksch, M. Greer   +8 more
semanticscholar   +1 more source

Extracorporeal photopheresis induces NETosis in neutrophils derived from patients with chronic graft‐vs‐host disease

Journal of clinical apheresis, 2023
Extracorporeal photopheresis (ECP) is considered an effective treatment for patients with chronic graft vs host disease (cGVHD) and demonstrates efficacy in ameliorating GVHD.
I. Goldberg, G. Granot, A. Telerman, S. Partouche, T. Shochat, Erez Halperin, A. Gafter-Gvili, Liat Shargian, M. Yeshurun, P. Raanani, O. Wolach, V. Yahalom   +11 more
semanticscholar   +1 more source