Results 81 to 90 of about 8,717 (203)

Dialogue Between the Clock Gene Bmal1 and Retinopathy: What Is the Exact Relationship?

CNS Neuroscience &Therapeutics, Volume 31, Issue 11, November 2025.
Circadian rhythm is offering novel insights into the pathogenesis of retinopathy. Bmal1, a key transcriptional regulator of the circadian clock, serves as a critical pathologic cofactor in retinal degeneration. Deficiency in Bmal1 contributes to a broad spectrum of retinal pathological alterations, and modulating the clock gene Bmal1 could potentially ...
Yongheng Cui, Haoyan Li, Wenhui Fan, Hao Wu, Jiale Wang, Chengkang Qu, Ning Pu, Ye Tao   +7 more
wiley   +1 more source

Persistent activation of transducin by bleached rhodopsin in salamander rods. [PDF]

, 1996
The hydrolysis-resistant GTP analogue GTP-gamma-S was introduced into rods isolated from the retina of the salamander Ambystoma tigrinum to study the origin of the persistent excitation induced by intense bleaching illumination.
Cornwall, MC, Fain, GL, Matthews, HR
core  

Synthesis of C8‐Vinyl Chlorophylls d and f Impairs Far‐Red Light Photoacclimation and Growth Under Far‐Red Light

Physiologia Plantarum, Volume 177, Issue 6, November/December 2025.
ABSTRACT The inducible biosynthesis of chlorophylls d and f enables a subset of specialised cyanobacteria to perform oxygenic photosynthesis under far‐red light—in the absence of visible wavelengths—via a process termed far‐red light photoacclimation. These pigments, like the more common chlorophylls a and b, typically carry an ethyl substituent at the
Afeefa K. Chaudhary, Lorenz K. Fuchs, Krzysztof Pawlak, Gregory F. Dykes, Royston Goodacre, Dennis J. Nürnberg, Daniel P. Canniffe   +6 more
wiley   +1 more source

Photoreceptor degeneration has heterogeneous effects on functional retinal ganglion cell types

The Journal of Physiology, Volume 603, Issue 21, Page 6599-6621, November 1, 2025.
Abstract figure legend Photoreceptor loss has heterogeneous effects on functional retinal ganglion cell (RGC) types. A, illustrations of cross‐sections of rd10 retinae at different time points during degeneration. Left: P30, rod degeneration has commenced, cones are still unaffected.
Nadine Dyszkant, Jonathan Oesterle, Yongrong Qiu, Merle Harrer, Timm Schubert, Dominic Gonschorek, Thomas Euler   +6 more
wiley   +1 more source

Determining Optimal Test Parameters for Assessing Dark Adaptation in People With Intermediate Age-Related Macular Degeneration [PDF]

, 2018
Purpose: The primary aim was to determine optimal test conditions for evaluating dark adaptation in intermediate age-related macular degeneration (iAMD) in order to minimize test time while maintaining diagnostic sensitivity.
Binns, A. M., Crabb, D. P., Edwards, L. A., Taylor, D. J.   +3 more
core   +1 more source

Exceptional Visual‐Opsin Coexpression and Phenotypic Diversity in Outer‐Retinal Photoreceptors of Caenophidian Snakes

Journal of Comparative Neurology, Volume 533, Issue 10, October 2025.
In snakes, profound differences in retinal architecture are observed between diurnal and nocturnal species. Additionally, in the rod‐dominated retinas of nocturnal snakes, coexpression of the cone opsins SWS1 and LWS in individual cones is common, while rhodopsin (RH1) is restricted to typical rods.
Einat Hauzman, Silke Haverkamp, Juliana H. Tashiro, Irene L. Gügel, Natalia F. Torello‐Viera, Thaís B. Guedes, Pavel Němec, Nicholas R. Casewell, Cassandra M. Modahl, Maria Ermelinda Oliveira, Ana Lúcia C. Prudente, Daniel O. Mesquita, Dora Fix Ventura, David J. Gower   +13 more
wiley   +1 more source

The effect of bleach duration and age on the ERG photostress test [PDF]

, 2011
Background: The ERG photostress test assesses the recovery of the focal 41 Hz ERG following exposure to a bright light that bleaches a significant proportion of photopigment.
AA Paupoo, Alison Binns, AM Binns, AM Binns, Ashley Wood, C Owsley, C Owsley, DA Newsome, DC Coile, GR Jackson, JM Bland, M Hollins, NL Mata, PN Dimitrov, RL Steinmetz, SH Sarks, TD Lamb, Tom Margrain, WAH Rushton, YH Aldebasi   +19 more
core   +1 more source

Dietary Omega‐3 Long‐Chain Polyunsaturated Fatty Acids Can Enhance Ecologically Relevant Cognitive Traits in Juvenile Brown Trout

Ecology and Evolution, Volume 15, Issue 10, October 2025.
With this study, we tested the role of dietary n‐3 LC PUFA on behaviour and cognition of brown trout Salmo trutta from different lacustrine and riverine populations. Secondly, we tested the ecological relevance of these traits evaluating fish resource acquisition in a semi‐natural stream mesocosm through the inspection of stomach contents.
Stefano Mari, Stefan Auer, Benedikte Austad, Pernilla Hansson, Simon Vitecek, Mourine J. Yegon, Libor Závorka   +6 more
wiley   +1 more source

G-Protein Coupled Receptor Kinase 2 Minimally Regulates Melanopsin Activity in Intrinsically Photosensitive Retinal Ganglion Cells.

PLoS ONE, 2015
Phosphorylation is a primary modulator of mammalian G-protein coupled receptor (GPCR) activity. The GPCR melanopsin is the photopigment of intrinsically photosensitive retinal ganglion cells (ipRGCs) in the mammalian retina. Recent evidence from in vitro
Timothy J Sexton, Russell N Van Gelder
doaj   +1 more source

Primate photopigments and primate color vision. [PDF]

Proceedings of the National Academy of Sciences, 1996
The past 15 years have brought much progress in our understanding of several basic features of primate color vision. There has been particular success in cataloging the spectral properties of the cone photopigments found in retinas of a number of primate species and in elucidating the relationship between cone opsin genes and their photopigment ...
openaire   +2 more sources