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Photorhabdusand a Host of Hosts

Annual Review of Microbiology, 2009
Photorhabdus is a member of the family Enterobacteriaceae that lives in a mutualistic association with a Heterorhabditis nematode worm. The nematode worm burrows into insect prey and regurgitates Photorhabdus, which goes on to kill the insect. The nematode feeds off the growing bacteria until the insect tissues are exhausted, whereupon they reassociate
Waterfield, Nick R.   +2 more
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The tc genes of Photorhabdus: a growing family

Trends in Microbiology, 2001
The toxin complex (tc) genes of Photorhabdus encode insecticidal, high molecular weight Tc toxins. These toxins have been suggested as useful alternatives to those derived from Bacillus thuringiensis for expression in insect-resistant transgenic plants.
N R, Waterfield   +4 more
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Identifying Anti-host Effectors in Photorhabdus

2016
The death of the insect host is an essential part of the life cycle of Photorhabdus, and as a result, this bacterium comes equipped with a dazzlingly large array of toxins and virulence factors that ensure rapid insect death. Elucidation of the key players in insect infection and mortality has therefore proved difficult using traditional ...
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The regulation of pathogenicity and mutualism in Photorhabdus

Current Opinion in Microbiology, 2006
Photorhabdus is a genus of insect-pathogenic bacteria that also maintains a mutualistic interaction with Heterorhabditid nematodes. Bacteria in this genus are members of the family Enterobacteriaceae and are, therefore, closely related to many important mammalian pathogens. This bacteria-nematode complex has been exploited as a biocontrol agent that is
Susan A, Joyce   +2 more
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Rho-modifying bacterial protein toxins from Photorhabdus species

Toxicon, 2016
Photorhabdus bacteria live in symbiosis with entomopathogenic nematodes. The nematodes invade insect larvae, where they release the bacteria, which then produce toxins to kill the insects. Recently, the molecular mechanisms of some toxins from Photorhabdus luminescens and asymbiotica have been elucidated, showing that GTP-binding proteins of the Rho ...
Jank, Thomas   +2 more
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Oral toxicity of Photorhabdus toxins against thrips species

Journal of Invertebrate Pathology, 2005
The oral toxicity of excretion products of several Photorhabdus and Xenorhabdus strains was tested on two thrips species: Frankliniella occidentalis and Thrips tabaci. Out of 46 Photorhabdus isolates and six Xenorhabdus isolates only six North American P. temperata isolates were toxic to the thrips species. After 7 days of drinking from P.
Gerritsen, L.J.M.   +2 more
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Generation of thermostable monomeric luciferases from Photorhabdus luminescens

Biochemical and Biophysical Research Communications, 2002
Bacterial luciferases and the genes encoding these light-emitting enzymes have an increasing number of applications in biological sciences. Temperature lability and the heterodimeric nature of these luciferases have been the major obstacles for their widespread use, for instance, as genetic reporters.
Annette, Westerlund-Karlsson   +2 more
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The Regulation of Secondary Metabolism in Photorhabdus

2016
A general definition of secondary metabolism is that it consists of the metabolic pathways and the products of metabolism that are not absolutely required for the survival of the organism. Using this definition, it is now well established that Photorhabdus elaborate an extensive secondary metabolism during the post-exponential phase of bacterial growth.
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Photorhabdus luminescens subsp. kleinii subsp. nov. (Enterobacteriales: Enterobacteriaceae)

Current Microbiology, 2010
Association between bacteria Photorhabdus and their nematode hosts Heterorhabditis represents one of the emerging models in symbiosis studies. In this study, we isolated the bacterial symbionts of the nematode Heterorhabditis georgiana. Using gyrB sequences for phylogenetic analysis, these strains were shown to be part of the species of Photorhbdus ...
Ruisheng, An, Parwinder S, Grewal
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Photorhabdus asymbiotica as an Insect and Human Pathogen

2016
Photorhabdus asymbiotica is a species of bacterium that is pathogenic to humans whilst retaining the ability to infect insect hosts. Currently, there are two recognised subspecies, P. asymbiotica subsp. asymbiotica and P. asymbiotica subsp. australis with strains isolated from various locations in the USA, Australia, Thailand, Nepal and Europe.
Alexia, Hapeshi, Nick R, Waterfield
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