Results 61 to 70 of about 5,937 (149)
Delivery Systems for Therapeutic Genome Editing: Challenges, Innovations, and Future Perspectives
MedComm, Volume 7, Issue 7, July 2026.Schematic illustration of four emerging CRISPR–Cas delivery platforms defined by distinct design principles and structural features: virus‐mimicking nanosystems (e.g., VLPs), cell‐derived extracellular vesicles, cell‐penetrating peptides, and stimuli‐responsive scaffolds. These platforms enable spatiotemporally controlled delivery of RNPs, mRNA, or DNA
Meijia Yang +9 more
wiley +1 more source
Microbial Biotechnology, Volume 19, Issue 6, June 2026.A heterologous T3SS turns Pseudomonas protegens Pf‐5 into a programmable molecular syringe that delivers Bg9562 into Fusarium hyphae, suppresses fungal pathogens, enhances rhizosphere colonization and protects tomato plants from wilt. This modular platform offers a transferable strategy for next‐generation fungal biocontrol.
Yuyuan Peng +15 more
wiley +1 more source
Phylogenetic tree of Photorhabdus.
, 2018 Maximum likelihood tree of a 588 bp of the recA region for 13 Photorhabdus isolates from Nam Nao National Park, Phetchabun Province, Thailand (codes ending with TH), together with 16 Photorhabdus sequences downloaded from the GenBank database ...
Raxsina Polseela (5089397) +5 more
core +1 more source
Transcript abundance of photorhabdus insect-related (Pir) toxin in Manduca sexta and Galleria mellonella infections [PDF]
, 2016 In this study, we assessed pirAB toxin transcription in Photorhabdus luminescens laumondii (strain TT01) (Enterobacteriaceae) by comparing mRNA abundance under in vivo and in vitro conditions.
Castagnola, Anaïs +14 more
core +1 more source
Discovery of H2 Receptor Antagonists as Colistin Enhancers by Targeting Acid Stress Response
Advanced Science, Volume 13, Issue 26, 8 May 2026.This study identifies YqgB as a key target for restoring colistin susceptibility in mcr‐positive pathogens under acidic conditions by remodeling phospholipid composition and reducing LPS modification. Deep learning‐based screening reveals H2 receptor antagonists as novel colistin adjuvants. Further investigations indicate that ranitidine and famotidine
Jinju Cai +7 more
wiley +1 more source
RUDN Journal of Medicine, 2013 The article presents results of clinical case. New pathogen, a gram-negative bacterium Photorhabdus asymbiotica, was isolated. Identified a new causative agent of acute pyelonephritis on the background of urolithiasis — a gram-negative bacterium ...
V P Avdoshin +4 more
doaj
Insects, 2020 The fruit fly Drosophila melanogaster forms a magnificent model for interpreting conserved host innate immune signaling and functional processes in response to microbial assaults.
Ioannis Eleftherianos, Upasana Sachar
doaj +1 more source
Agricultural and Forest Entomology, Volume 28, Issue 2, Page 298-313, May 2026.Out of 136 identified EPNs, only 18 (8 Steinernema and 6 Heterorhabditis) are commercialised globally, highlighting a major gap between discovery and application. High production costs and inconsistent field efficacy are the leading obstacles to the widespread commercialisation of EPN‐based biocontrol products.
Ndivhuwo Ramatsitsi +2 more
wiley +1 more source
eLife, 2019 Photorhabdus is a highly effective insect pathogen and symbiont of insecticidal nematodes. To exert its potent insecticidal effects, it elaborates a myriad of toxins and small molecule effectors.
Isabella Vlisidou +5 more
doaj +1 more source
Genetic Variation in Chemical Defence Affects Protection of an Herbivorous Insect Against Predation
Molecular Ecology, Volume 35, Issue 9, May 2026.ABSTRACT Genetic variation contributes to intraspecific differences in the chemical defence in many insect species, yet the underlying genetic mechanisms remain poorly understood. The horseradish flea beetle, Phyllotreta armoraciae, sequesters glucosinolates from its horseradish host plant and activates them using endogenous myrosinase enzymes.
Johannes Körnig +9 more
wiley +1 more source