Results 111 to 120 of about 17,615 (249)

Melanopsin‐Mediated Post‐Illumination Pupillary Response in Idiopathic Rapid Eye Movement (REM) Sleep Behavior Disorder and Parkinson's Disease

open access: yesMovement Disorders, EarlyView.
Abstract Aims To conduct a case–control study to investigate melanopsin‐mediated post‐illumination pupillary response (PIPR) in patients with Parkinson's disease (PD), video‐polysomnography‐confirmed isolated/idiopathic rapid eye movement (REM) sleep behavior disorder (iRBD), and age‐matched healthy controls (HC). Methods PIPR was measured at 6 s after
Joey W.Y. Chan   +16 more
wiley   +1 more source

Small‐Molecule Kinase Inhibitors Modulating Circadian Rhythms

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT The circadian clock mechanism generates 24‐h rhythms crucial for regulating various physiological processes, and its dysregulation has been implicated in numerous diseases. In cells, the circadian clock operates through a transcriptional‐translational feedback loop, where phosphorylation plays a pivotal role in maintaining accurate circadian ...
Irene Castellino   +3 more
wiley   +1 more source

Peptide‐based antibacterial nanoplatforms: Design principles, stimuli‐regulated behaviors, and applications

open access: yesResponsive Materials, EarlyView.
Peptide‐based antibacterial nanoplatforms, encompassing self‐assembled peptides and peptide‐engineered inorganic, polymeric, and lipid nanocarriers, are systematically reviewed. The article highlights design principles and stimuli‐responsive regulation for improving peptide stability, delivery efficiency, and antibacterial performance.
Peng Tan   +8 more
wiley   +1 more source

Small‐Scale Magnetic Soft Robots for Medical Applications: From Laboratory to Clinical Use

open access: yesSmartBot, EarlyView.
Small‐scale magnetic soft robots are emerging as promising platforms for minimally invasive diagnosis and therapy in complex in vivo environments. This review compares untethered and tethered medical magnetic robots in parallel across five translational stages, from basic performance testing to clinical evaluation.
Xingxing Ke   +29 more
wiley   +1 more source

Neuropsychological influences on visual photosensitivity and its treatment in traumatic brain injury. [PDF]

open access: yesBMJ Open Ophthalmol
Bhatt S   +16 more
europepmc   +1 more source

Recent Advances in Photocatalyst‐Driven Protein Labeling and Proximity Mapping

open access: yesThe Chemical Record, EarlyView.
Photocatalyst‐driven protein labeling and proximity mapping have rapidly advanced as powerful strategies for spatiotemporal control in complex biological environments. This review integrates recent developments across single‐electron transfer and energy transfer‐based mechanisms and highlights how catalyst design, reactive intermediates, and diffusion ...
Shinichi Sato   +3 more
wiley   +1 more source

Skin health in oncology: evidence-based skin care for cancer patients. [PDF]

open access: yesOncologist
Kaminsky A   +5 more
europepmc   +1 more source

Printing to Fight Antimicrobial Resistance Through Nano/Microstructured Platforms

open access: yesThe Chemical Record, EarlyView.
Additive manufacturing enables the rational design of structured antimicrobial platforms across multiple length scales, from nanofibrous scaffolds and droplet microreactors to 3D and 4D printed constructs. By engineering confinement, interfacial chemistry, and stimuli‐responsive release, these systems exert localized action through complementary ...
Giorgia Puleo   +11 more
wiley   +1 more source

Peptide‐directed nanovehicles enabling tumor‐selective ROS amplification and antitumor immunity

open access: yesVIEW, EarlyView.
Cancer cells are vulnerable to oxidative stress, yet exploit immune tolerance to escape destruction. In contrast, their metabolic profile is markedly altered to support rapid proliferation, accompanied by elevated production of reactive oxygen species (ROS).
Manuela Calin   +3 more
wiley   +1 more source

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