Results 151 to 160 of about 15,911 (308)

The role of ClpX in erythropoietic protoporphyria

open access: yesHematology, Transfusion and Cell Therapy, 2018
Hemoglobin is an essential biological component of human physiology and its production in red blood cells relies upon proper biosynthesis of heme and globin protein.
Jared C. Whitman   +2 more
doaj  

Phytochemicals in Cancer Therapy: A Structured Review of Mechanisms, Challenges, and Progress in Personalized Treatment

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT Cancer is a major global health concern. Therefore, new treatment options are needed. The phytochemicals have different chemical structures. It also exhibits several other biological activities. Therefore, these compounds are promising anticancer agents. This review aims to identify and assess new candidates for anticancer therapy. Researchers
Alaa A. A. Aljabali   +11 more
wiley   +1 more source

Lower lip squamous cell carcinoma in patients with photosensitive disorders: Analysis of cases treated at the Brazilian National Cancer Institute (INCA) from 1999 to 2012

open access: gold, 2017
JFP Borges   +7 more
openalex   +1 more source

Photo‐triggered Hyaluronic Acid Hydrogel for 3D Culture and Cell Recovery

open access: yesChemBioChem, Accepted Article.
Properties of semi‐synthetic hydrogels can be fine‐tuned making these attractive for various applications in regenerative medicine. Here, we describe a hydrogel platform based on hyaluronic acid (HA) modified by (1R,8S,9S)‐bicycle[6.1.0]non‐4‐yn‐9‐ylmethanol (BCN) and a cross‐linker composed of light sensitive o‐nitrobenzyl and polyethylene glycol (PEG)
Francesco Palmieri   +8 more
wiley   +1 more source

Development and Recent Advances in SLIPT‐PM: A Chemogenetic Platform for Manipulating Signaling at the Plasma Membrane

open access: yesChemBioChem, EarlyView.
SLIPT‐PM enables the translocation of tag‐fused proteins from the cytoplasm to the plasma membrane using a synthetic self‐localizing ligand. This user‐friendly system permits reversible control of diverse signaling pathways. This concept article highlights the key features and current applications of SLIPT‐PM as a powerful tool in chemical and ...
Shuya Ohira   +3 more
wiley   +1 more source

Investigating the mechanisms of capsicum in age‐related hearing loss: Based on network pharmacology

open access: yesEye &ENT Research, EarlyView.
Abstract Background To explore the material basis and action mechanism of the chemical component gene of pepper on presbycusis, and to provide a reference for the traditional Chinese medicine treatment of age‐related hearing loss (ARHL). Methods The chemical composition and action targets of traditional Chinese medicine flavor of pepper were searched ...
Yan Wang   +9 more
wiley   +1 more source

Epilepsy syndromes classification

open access: yesEpilepsia Open, EarlyView.
Abstract Epilepsy syndromes are distinct electroclinical entities which have been recently defined by the International League Against Epilepsy Nosology and Definitions Task Force. Each syndrome is associated with “a characteristic cluster of clinical and EEG features, often supported by specific etiologic findings”.
Elaine C. Wirrell   +4 more
wiley   +1 more source

Quantitative magnetic resonance imaging traits as endophenotypes for genetic mapping in epilepsy. [PDF]

open access: yes
Over the last decade, the field of imaging genomics has combined high-throughput genotype data with quantitative magnetic resonance imaging (QMRI) measures to identify genes associated with brain structure, cognition, and several brain-related disorders.
Alhusaini, S   +3 more
core  

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