Results 81 to 90 of about 2,878,066 (285)

Emerging Therapeutic Strategies for Hearing Loss

open access: yesAdvanced Therapeutics, EarlyView.
Challenges still exist in treating hearing loss in cases of severe damage to hair cells or spiral ganglion neurons. Here, a schematic diagram of cochlear sensory hair cells and auditory nerves is presented. It is found that in normal Corti organs, hair cells have upright stereocilia at the top and auditory neurons at the base. Ototoxic drugs, noise, or
Shanying Han   +9 more
wiley   +1 more source

Advances in Microfluidic Cochlea‐On‐A‐Chip

open access: yesAdvanced Science, EarlyView.
This review systematically examines diverse cell sources for inner ear organoids and outlines stepwise induction protocols. Furthermore, it discusses current applications and prospective developments of cochlea‐on‐a‐chip technologies in areas such as deafness modeling, mechanistic studies, and drug evaluation, with particular focus on gene‐therapy drug
Tian Shen   +10 more
wiley   +1 more source

Kindler′s syndrome: A case series of three Indian children

open access: yesIndian Journal of Dermatology, 2010
Kindler′s syndrome is a very rare genodermatosis characterized by acral blistering starting in infancy, photosensitivity, progressive poikiloderma, cutaneous atrophy, and various forms of mucosal involvement.
Ghosh Sudip   +4 more
doaj  

IncRNA‐ZFAS1, an Emerging Gate‐Keeper in DNA Damage‐Dependent Transcriptional Regulation

open access: yesAdvanced Science, EarlyView.
LncZFAS1 plays a crucial role during DNA damage response in mammalian cells. Loss of lncZFAS1 results in deficient DNA lesion removal and reduced cell viability. Mechanistically, lncZFAS1 modulates RNAPII phosphorylation and transcription and thereby promotes both GG‐NER and TC‐NER upon UV damage.
Jiena Liu   +10 more
wiley   +1 more source

Advancements in Bio‐Integrated Flexible Electronics for Hemodynamic Monitoring in Cardiovascular Healthcare

open access: yesAdvanced Science, EarlyView.
This review explores the cutting‐edge development of bio‐integrated flexible electronics for real‐time hemodynamic monitoring in cardiovascular healthcare. It covers key physiological indicators, innovative sensing mechanisms, and materials considerations. This paper highlights the application of both invasive and non‐invasive devices in cardiovascular
Ke Huang, Zhiqiang Ma, Bee Luan Khoo
wiley   +1 more source

Myositis-specific and myositis-associated autoantibody profiles and their clinical associations in a large series of patients with polymyositis and dermatomyositis

open access: yesClinics, 2013
OBJECTIVE: To analyze the prevalence of myositis-specific and myositis-associated autoantibodies and their clinical correlations in a large series of patients with dermatomyositis/polymyositis.
Marcela Gran Pina Cruellas   +4 more
doaj   +1 more source

Natural Carotenoids a Weapon to Fightagainst Life Style Related Disorders

open access: yes, 2018
Carotenoids have gained consumer interest because of their unique biological functions to promote human health. They belong to a group of isoprenoid pigments with abundance in nature.
Shabbir U, Nuzhat H
semanticscholar   +1 more source

Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine

open access: yesAdvanced Science, EarlyView.
Neural organoids provide a versatile platform for neurological research. Advances in organoid technology have partially achieved human neural tissue complexity in terms of tissue structure, cell diversity, and neural signaling, offering insights into neural disorders and regenerative strategies. Technology advances from biomaterials, bio‐manufacturing,
Ruiqi Huang   +4 more
wiley   +1 more source

High‐Gain PMMA‐Modified Graphene Photodetectors for Dual‐Wavelength Secure Communication Utilizing Distinct Temporal Photoresponses

open access: yesAdvanced Science, EarlyView.
The bipolar photoresponses with temporally distinguishable characteristics in a PMMA‐modified graphene photodetector are successfully achieved. Through systematic harnessing of these wavelength‐dependent temporal dynamics as encrypted and key signals, an effective encryption system for optical communication systems is developed.
Jinhua Wu   +5 more
wiley   +1 more source

Seven- and 23-year-old Siblings with Papulonodular Lesions after Sun Exposure: A Quiz

open access: yesActa Dermato-Venereologica, 2021
Davide Neri   +4 more
doaj   +1 more source

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