Results 61 to 70 of about 1,280,422 (280)

Amiodarone-associated optic neuropathy in the treatment of cardiovascular diseases

Российский офтальмологический журнал, 2020
An increase in the growth of cardiovascular diseases has been observed in the last few years. Cardiac rhythm disturbances, especially atrial fibrillation, in absence of cardioversion and proper prophylaxis lead to thromboembolic complications.
E. E. Ioyleva, N. A. Gavrilova, A. V. Zinov’eva, M. V. Kats   +3 more
doaj   +1 more source

Melanopsin, photosensitive ganglion cells, and seasonal affective disorder

Neuroscience & Biobehavioral Reviews, 2013
In two recent reports, melanopsin gene variations were associated with seasonal affective disorder (SAD), and in changes in the timing of sleep and activity in healthy individuals. New studies have deepened our understanding of the retinohypothalamic tract, which translates environmental light received by the retina into neural signals sent to a set of
Roecklein, Kathryn A, Wong, Patricia M, Miller, Megan A, Donofry, Shannon D, Kamarck, Marissa L, Brainard, George C   +5 more
openaire   +3 more sources

Integrated Photoelectrode and Electrolyte Engineering via Carbon Quantum Dots for Self‐Powered H2O/O2‐Mediated Portable Photoelectrochemical Cells

Advanced Science, EarlyView.
Surface‐charged N‐CQDs serve as both electrolyte additives and photocathode modifiers. Electrodeposited N‐CQDs on Cu2O form a stable composite, steering 4e− ORR toward water. A quasi‐solid electrolyte with N‐CQDs aids charge migration, electrode‐electrolyte interfacial compatibility and replenishes active sites.
Yang Wu, Hui‐Min Duan, Chen‐Guang Li, Tian‐Xu Zeng, Jian‐Long Li, Xue‐Tong Cheng, Yun Jing, Wei‐Zhe Li, Qing Li, Xu Tian, Jiwu Zhao, Anders Thapper, Hong‐Yan Wang   +12 more
wiley   +1 more source

The face of Non‐photosensitive trichothiodystrophy phenotypic spectrum: A subsequent study on paediatric population

Molecular Genetics & Genomic Medicine
Background Non‐photosensitive trichothiodystrophies (TTDs) are a diverse group of genodermatoses within the subset of conditions known as “sulphur‐deficient brittle hair” syndromes.
Giulia Pascolini, Martina Lipari, Federica Gaudioso, Luca Fania, Giovanni Di Zenzo, Biagio Didona   +5 more
doaj   +1 more source

Topiramate-Induced Acute Myopia, Diplopia, and Photosensitivity: A Case Report

Beyoglu Eye Journal, 2019
Topiramate is primarily used as an antiepileptic drug. It has also demonstrated effectiveness in migraine prophylaxis, depression, trigeminal neuralgia, bipolar disorders, and idiopathic intracranial hypertension. The drug has a large number of potential
Murat Kocamaz, Onur Karadag
doaj   +1 more source

Primary Cutaneous CD30+ Anaplastic Large T Cell Lymphoma in a Patient Treated with Cyclosporine for Actinic Reticuloid

Case Reports in Dermatological Medicine, 2020
Actinic reticuloid (AR)—a subtype of chronic actinic dermatitis—clinically and histopathologically shows lymphoma-like features. We report a male patient initially diagnosed with erythrodermic cutaneous T cell lymphoma (CTCL) who developed severe ...
T. Gambichler, N. Patsinakidis, L. Susok, M. H. Segert, M. Doerler   +4 more
doaj   +1 more source

UBE2O Drives Immune Evasion and Radioimmunotherapy Resistance in Lung Cancer by Degrading CDKL1 to Induce PD‐L1 Transcription

Advanced Science, EarlyView.
UBE2O targets CDKL1 for the degradation to upregulate PD‐L1 expression and promotes resistance to radioimmunotherapy in lung cancer, supporting the potential of targeting UBE2O as a promising therapeutic strategy. ABSTRACT Resistance to radioimmunotherapy is one of the primary causes of treatment failure in lung cancer patients; however, the underlying
Huichan Xue, Xiaohua Jie, Zhiwei Liu, Ruoxin Fang, Shuo Wu, Xiaorong Dong, Shuangbing Xu   +6 more
wiley   +1 more source

PFKFB4 Deubiquitination by USP10 Enhances Fumarate Metabolism to Orchestrate the KDM1A/Rad51 Axis and Confer Radioresistance in Lung Cancer

Advanced Science, EarlyView.
USP10 binds to and stabilizes PFKFB4, enhancing glycolytic ATP production, which activates the urea cycle and elevates fumarate. This inhibits histone demethylase KDM1A, leading to increased H3K4me1 enrichment at the Rad51 promoter and direct activation of Rad51 transcription, which confers lung cancer radioresistance. The PFKFB4 inhibitor 5MPN targets
Yunshang Chen, Zilong Wu, Yongqiang Yang, Ruoxin Fang, Huichan Xue, Rui Zhou, Gang Wu, Xiaohua Jie   +7 more
wiley   +1 more source

Review of Gastrointestinal Capsule Robots: Materials, Actuation, Diagnostics, and Therapeutics

Advanced Science, EarlyView.
This review examines gastrointestinal capsule robots through a systems engineering lens, covering shell materials, actuation and localization strategies, diagnostic modalities, therapeutic interventions, and commercialization status. By mapping the complete technological chain from fabrication to clinical deployment, this work identifies critical gaps ...
Zengsheng Li, Zhongguo Ren, Yiliang Lin, Xianfeng Xia, Tianlong Li, Kai Fung Chan, Philip Wai Yan Chiu, Wei Peng Yong, Mengmeng Sun   +8 more
wiley   +1 more source

Photodistributed toxic epidermal necrolysis in association with lamotrigine and tanning bed exposure

JAAD Case Reports, 2021
Kristen Russomanno, MD, Ashley DiLorenzo, MD, Joshua Horeczko, BA, Min Deng, MD, Michael Cardis, MD, Vesna Petronic-Rosic, MD, MSc, MBA, Laura S. Johnson, MD, Helena B. Pasieka, MD, MS   +7 more
doaj   +1 more source