Results 41 to 50 of about 17,615 (249)

Waveguide Photoactuators: Materials, Fabrication, and Applications

Advanced Robotics Research, EarlyView.
Waveguide photoactuators convert guided light into mechanical motion. Their tethered‐flexible design enables minimally invasive surgery and confined‐space robotics. This review aims to guide materials selection, device design, and system integration, accelerating the transition of waveguide photoactuators from laboratory prototypes to versatile ...
Minjie Xi, Hemin Pan, Yang Zong, Yongfeng Mei, Jizhai Cui   +4 more
wiley   +1 more source

Clinical analysis of CHD2 gene mutations in pediatric patients with epilepsy

Pediatric Investigation, 2022
Importance CHD2 is a member of the chromodomain helicase DNA‐binding (CHD) family of proteins, which have important roles in the regulation of gene expression. Dysregulation of this protein may lead to various disorders.
Weixing Feng, Fang Fang, Xiaohui Wang, Chunhong Chen, Junlan Lu, Jie Deng   +5 more
doaj   +1 more source

Intravital Multimodal Imaging of Human Cortical Organoid Transplantation in a Mouse Model of Chronic Stroke

Advanced Science, EarlyView.
A multimodal intravital imaging platform enables longitudinal tracking of human cortical organoids transplanted into chronic stroke lesions. By combining surgical microscopy, MRI, bioluminescence imaging, and two‐photon fluorescence microscopy, the platform captures graft placement, viability dynamics, and cellular‐scale morphology in vivo, offering a ...
Jinghui Wang, Guanda Qiao, Honglin Tan, Colleen Russel, Baixuan Yang, Mengyang Jacky Li, Kexin Wang, Jiadi Xu, Chengyan Chu, Miroslaw Janowski, Tian‐Ming Fu, Piotr Walczak, Yajie Liang   +12 more
wiley   +1 more source

Evaluation of the Effectiveness of Sunscreens for Photosensitive Disorders

Nishi Nihon Hifuka, 2011
2009年5月から12月の7ヵ月間に5施設の医療機関を受診した光線過敏症患者およびエリテマトーデスなど日光により増悪を来す疾患患者49例に対し，日光露光部へのサンスクリーン剤3製品の4週間の使用試験を実施した。サンスクリーン剤は，紫外線吸収剤を含まず紫外線散乱剤として微粒子酸化チタンを配合した「ノブ®UVローションEX」，「ノブ®UVシールドEX」および「ノブ®UVスティックEX」である。2例において，塗布部位での紅斑やそう痒にて使用を中止したが，皮膚症状は中止数日後に軽快した。また使用中止を除いた47例において，試験前後に担当医師による皮膚所見を得るとともに，テープストリッピング法により得た表皮角層から，酸化タンパクおよびTNF-αの測定を行い，試験前後の有意な差を認めた。さらに ...
FUKUNAGA, Atsushi, NISHIGORI, Chikako, ITO, Kei, SHIMIZU, Hiroshi, SASAKI, Rikako, KATO, Mayumi, MIYACHI, Yoshiki, TAKEUCHI, Satoshi, TASHIRO, Akari, FURUE, Masutaka   +9 more
openaire   +1 more source

HNRNPD Induces Radioresistance in Nasopharyngeal Carcinoma by Sequestering GRAMD4 mRNA in Stress Granules

Advanced Science, EarlyView.
HNRNPD promotes radioresistance in nasopharyngeal carcinoma by enhancing stress granule assembly and sequestering GRAMD4 mRNA. This suppresses GRAMD4 translation and inhibits mitochondrial apoptosis. Targeting the integrated stress response with ISRIB restores GRAMD4 expression and sensitizes tumors to radiotherapy, revealing a translational control ...
Yingzi Li, Tong Xiang, Yuanyuan Liu, Desheng Weng, Jingjing Zhao, Hao Chen, Yan Tang, Songzuo Xie, Hao Zhang, Jun Luo, Xinyi Yang, Qiuzhong Pan, Muping Di, Jianchuan Xia   +13 more
wiley   +1 more source

Prefrontal cortex neurons encode ambient light intensity differentially across regions and layers

Nature Communications
While light can affect emotional and cognitive processes of the medial prefrontal cortex (mPFC), no light-encoding was hitherto identified in this region. Here, extracellular recordings in awake mice revealed that over half of studied mPFC neurons showed
Elyashiv Zangen, Shira Hadar, Christopher Lawrence, Mustafa Obeid, Hala Rasras, Ella Hanzin, Ori Aslan, Eyal Zur, Nadav Schulcz, Daniel Cohen-Hatab, Yona Samama, Sarah Nir, Yi Li, Irina Dobrotvorskia, Shai Sabbah   +14 more
doaj   +1 more source

Amiodarone-associated optic neuropathy in the treatment of cardiovascular diseases

Российский офтальмологический журнал, 2020
An increase in the growth of cardiovascular diseases has been observed in the last few years. Cardiac rhythm disturbances, especially atrial fibrillation, in absence of cardioversion and proper prophylaxis lead to thromboembolic complications.
E. E. Ioyleva, N. A. Gavrilova, A. V. Zinov’eva, M. V. Kats   +3 more
doaj   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Topiramate-Induced Acute Myopia, Diplopia, and Photosensitivity: A Case Report

Beyoglu Eye Journal, 2019
Topiramate is primarily used as an antiepileptic drug. It has also demonstrated effectiveness in migraine prophylaxis, depression, trigeminal neuralgia, bipolar disorders, and idiopathic intracranial hypertension. The drug has a large number of potential
Murat Kocamaz, Onur Karadag
doaj   +1 more source

Primary Cutaneous CD30+ Anaplastic Large T Cell Lymphoma in a Patient Treated with Cyclosporine for Actinic Reticuloid

Case Reports in Dermatological Medicine, 2020
Actinic reticuloid (AR)—a subtype of chronic actinic dermatitis—clinically and histopathologically shows lymphoma-like features. We report a male patient initially diagnosed with erythrodermic cutaneous T cell lymphoma (CTCL) who developed severe ...
T. Gambichler, N. Patsinakidis, L. Susok, M. H. Segert, M. Doerler   +4 more
doaj   +1 more source