Results 51 to 60 of about 1,280,422 (280)

New Methods for Quantification of Visual Photosensitivity Threshold and Symptoms

, 2017
Visual photosensitivity is a common subjective symptom found in many conditions including ocular disorders and neurological disorders such as achromatopsia, migraine and traumatic brain injury.
Byron L. Lam, MD
core   +2 more sources

Evaluation of the Effectiveness of Sunscreens for Photosensitive Disorders

Nishi Nihon Hifuka, 2011
2009年5月から12月の7ヵ月間に5施設の医療機関を受診した光線過敏症患者およびエリテマトーデスなど日光により増悪を来す疾患患者49例に対し，日光露光部へのサンスクリーン剤3製品の4週間の使用試験を実施した。サンスクリーン剤は，紫外線吸収剤を含まず紫外線散乱剤として微粒子酸化チタンを配合した「ノブ®UVローションEX」，「ノブ®UVシールドEX」および「ノブ®UVスティックEX」である。2例において，塗布部位での紅斑やそう痒にて使用を中止したが，皮膚症状は中止数日後に軽快した。また使用中止を除いた47例において，試験前後に担当医師による皮膚所見を得るとともに，テープストリッピング法により得た表皮角層から，酸化タンパクおよびTNF-αの測定を行い，試験前後の有意な差を認めた。さらに ...
FUKUNAGA, Atsushi, NISHIGORI, Chikako, ITO, Kei, SHIMIZU, Hiroshi, SASAKI, Rikako, KATO, Mayumi, MIYACHI, Yoshiki, TAKEUCHI, Satoshi, TASHIRO, Akari, FURUE, Masutaka   +9 more
openaire   +1 more source

Intravital Multimodal Imaging of Human Cortical Organoid Transplantation in a Mouse Model of Chronic Stroke

Advanced Science, EarlyView.
A multimodal intravital imaging platform enables longitudinal tracking of human cortical organoids transplanted into chronic stroke lesions. By combining surgical microscopy, MRI, bioluminescence imaging, and two‐photon fluorescence microscopy, the platform captures graft placement, viability dynamics, and cellular‐scale morphology in vivo, offering a ...
Jinghui Wang, Guanda Qiao, Honglin Tan, Colleen Russel, Baixuan Yang, Mengyang Jacky Li, Kexin Wang, Jiadi Xu, Chengyan Chu, Miroslaw Janowski, Tian‐Ming Fu, Piotr Walczak, Yajie Liang   +12 more
wiley   +1 more source

One photon and two photon process in photo-decomposition of germanium oxygen deficient centres

, 1997
There has been much debate on the fundamental mechanism of photosensitivity in germanium-doped silica optical fibres. The importance of the effect, which was discovered by K.O.Hill in 1978, has been well demonstrated by the still rapidly increasing ...
Dong, L., Bagratashvili, V.N., Tsypina, S.I.   +2 more
core   +1 more source

Photosensitivity From Avapritinib: Pharamacovigilance Analysis

, 2022
Certain protein kinase inhibitors have been reported to cause photosensitivity. Avapritinib is a tyrosine kinase inhibitor that was approved in January 2020.
Brandon Chu, Ajit Venkatakrishnan, Pushkar Aggarwal   +2 more
core   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Clinical analysis of CHD2 gene mutations in pediatric patients with epilepsy

Pediatric Investigation, 2022
Importance CHD2 is a member of the chromodomain helicase DNA‐binding (CHD) family of proteins, which have important roles in the regulation of gene expression. Dysregulation of this protein may lead to various disorders.
Weixing Feng, Fang Fang, Xiaohui Wang, Chunhong Chen, Junlan Lu, Jie Deng   +5 more
doaj   +1 more source

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

Advanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale, Marie Celine Lefevre, Alessio Carmignani, Maria Cristina Ceccarelli, Matteo Battaglini, Attilio Marino, Gianni Ciofani   +6 more
wiley   +1 more source

Prefrontal cortex neurons encode ambient light intensity differentially across regions and layers

Nature Communications
While light can affect emotional and cognitive processes of the medial prefrontal cortex (mPFC), no light-encoding was hitherto identified in this region. Here, extracellular recordings in awake mice revealed that over half of studied mPFC neurons showed
Elyashiv Zangen, Shira Hadar, Christopher Lawrence, Mustafa Obeid, Hala Rasras, Ella Hanzin, Ori Aslan, Eyal Zur, Nadav Schulcz, Daniel Cohen-Hatab, Yona Samama, Sarah Nir, Yi Li, Irina Dobrotvorskia, Shai Sabbah   +14 more
doaj   +1 more source

Advances and Perspectives in Graphene‐Based Quantum Dots Enabled Neuromorphic Devices

Advanced Science, EarlyView.
Graphene‐based QDs are zero‐dimensional carbon nanomaterials with pronounced quantum confinement and tunable electronic structures. Herein, we summarize their synthesis strategies and functionalization methods, and highlight their functional roles and operating mechanisms in devices, as well as recent advances in neuromorphic electronics. We anticipate
Yulin Zhen, Wei Zeng, Zherui Zhao, JiYu Zhao, Ziyan Huang, Zhuo Chen, Kui Zhou, Guanglong Ding, Su‐Ting Han, Ye Zhou   +9 more
wiley   +1 more source