Results 171 to 180 of about 6,309 (244)

Antibacterial Hydrogel Dressing With Ca2+‐Dependent Hyaluronidase Responsiveness for Accelerating Wound Healing via On‐Demand Release of AIE Photosensitizers

Exploration, EarlyView.
This study innovates a Ca2+‐responsive hydrogel dressing that releases AIE photosensitizers on‐demand. Low Ca2+ enhances bacterial hyaluronidase (HAase) activity, degrading hyaluronic acid dressing to trigger antibacterial ROS release, while high Ca2+ inhibits HAase, preventing overdosing.
Rongwei Cui, Hao Yang, Miaomiao Kang, Zhijun Zhang, Weilin Xu, Yang Jiang, Lizhou Xu, Xiao‐Yong Zhan, Luhan Zhang, Yunsheng Xu, Dong Wang, Ben Zhong Tang, Danyang Li   +12 more
wiley   +1 more source

Asymmetric Lip Hyperpigmentation in a Transplant Patient. [PDF]

Dermatopathology (Basel)
Kimpe V, Alvarez Martinez D, Menzinger S, Kaya G.   +3 more
europepmc   +1 more source

Immunosuppressive Microenvironment Reprogramming by Synergistic Sonodynamic Therapy of Phthalocyanine‐MOF Hybrids for Hepatocellular Carcinoma

Exploration, EarlyView.
Hepatocellular carcinoma presents a formidable clinical challenge, constructing a hypoxic and immunosuppressive microenvironment that renders conventional therapies largely ineffective. In response, we have developed Pc@Zr‐MOF, a phthalocyanine‐integrated metal‐organic framework hybrid engineered to penetrate this defensive barrier.
Han Wu, Lihui Gu, Jiahao Xu, Chuyue Zhang, Mingda Wang, Chao Li, Lanqing Yao, Yongkang Diao, Yuchen Li, Fujie Chen, Huixuan Fan, Yuze Zhao, Feng Shen, Tian Yang   +13 more
wiley   +1 more source

Impact of ecological UV radiation on the photochemistry of nuclear DNA. [PDF]

Biophys Rev
Sánchez AG, Gabrielli A, Keszenman DJ.
europepmc   +1 more source

Visible Photosensitizing Disinfectant Spray for Combating Multidrug‐Resistant Candidozyma Auris in Healthcare Settings

Exploration, EarlyView.
We designed and synthesized a dual‐type AIE photosensitizer (named TB) spray, containing a cationic quaternary ammonium unit and a glycosyl‐targeted boronic acid moiety, characterized for the elimination of biofilm infections of Candidozyma auris (C. auris) on high‐touch surfaces.
Xiaoyu Xu, Ming‐Yu Wu, Baoping Li, Jie Li, Siyu Chen, Luojia Chen, Donghu Yu, Liupiaopiao Yang, Ziyu Hong, Huaqin Pan, Wei Xiang, Shun Feng, Jong Seung Kim, Lianrong Wang, Zhiqiang Li, Shi Chen, Meijia Gu   +16 more
wiley   +1 more source

Leveraging the Aminothiol-Specific Phosphorogenic Response of Iridium(III) Thioester Complexes for the Development of Intracellular Sensors and Cancer Phototherapeutics. [PDF]

JACS Au
Mak EC, Chen Z, Lee LC, Yan LL, Yam VW, Lo KK.   +5 more
europepmc   +1 more source

Microengineering the Liver: Strategies for Constructing Functional Liver‐on‐a‐Chip Devices

Exploration, EarlyView.
This review summarizes recent advances in liver‐on‐a‐chip (LOC) technologies, including fabrication strategies and functional integration approaches, and discusses their promising applications in drug screening and related biomedical fields. ABSTRACT Reliable in vitro liver models are indispensable for researching liver diseases and developing ...
Jie Wang, Ziwei Liang, Jiapu Wang, Zongyi Li, Shaojie Wang, Yan Wei, Xin Xie, Di Huang   +7 more
wiley   +1 more source

High Quantum Yields and Biomedical Fluorescent Imaging Applications of Photosensitized Trivalent Lanthanide Ion-Based Nanoparticles. [PDF]

Int J Mol Sci
Tegafaw T, Zhao D, Liu Y, Yue H, Saidi AKAA, Baek A, Kim J, Chang Y, Lee GH.   +8 more
europepmc   +1 more source

Advanced extracellular vesicle immunotherapy

FlexMat, EarlyView.
A diagrammatic depiction of the therapeutic applicability of extracellular vesicles (EVs) in immunotherapy. This review explores the dual roles of tumor‐derived and immune cell‐derived EVs in cancer immunotherapy, discusses recent progress in EV engineering that improve their clinical utility, and evaluates their potential to augment existing ...
Jingjing Zhang, Yunfei Mu, Xianyue Ji, Xiaoting Jiang, Ruiheng Wang, Xianguang Ding, Lianhui Wang   +6 more
wiley   +1 more source

Nanostructural and nanomechanical alterations of photosensitized lipid membranes due to light induced formation of reactive oxygen species. [PDF]

Sci Rep
Zolcsák Á, Kiss B, Bozó T, Somkuti J, Vona I, Kellermayer M, Herenyi L.   +6 more
europepmc   +1 more source