Results 151 to 160 of about 44,938 (292)

Photoactivated Platinum Complexes: Targeting Membrane Proteins and Organelles for Precision Cancer Therapy

open access: yesAngewandte Chemie, EarlyView.
This review highlights an emerging anticancer approach integrating platinum agents into photodynamic therapy (PDT) and photoactivated chemotherapy (PACT) systems, further augmented by cancer cell membrane‐ and organelle‐targeting. By directing photoactivated platinum complexes from nontargeted distribution to cancer cells or defined subcellular sites ...
Shu Chen   +3 more
wiley   +2 more sources

Self-assembly of Mitochondria-targeted Photosensitizer to Increase Photostability and Overcome Hypoxia in Photodynamic Therapy

open access: yes, 2019
The development of photosensitizer for cancer photodynamic therapy has been challenged due to its low photostability and therapeutic inefficacy under hypoxic tumor microenvironment.
Ryu, Ja-Hyoung   +3 more
core  

Acetylene Semi‐Hydrogenation by Photocatalysis

open access: yesAngewandte Chemie, EarlyView.
Photocatalytic acetylene semi‐hydrogenation is an emerging light‐driven route to polymer‐grade ethylene, offering a mild alternative to energy‐intensive thermocatalysis. By replacing H2 co‐feed with water or other proton sources, these systems can achieve high selectivity under ambient conditions.
Anna Fortunato   +6 more
wiley   +2 more sources

ALDH Inhibition‐Primed Photocatalysis Disrupts Cancer Stemness Plasticity

open access: yesAngewandte Chemie, EarlyView.
DE‐Et converts ALDH‐mediated redox buffering into a photoredox vulnerability by coupling ALDH inhibition with red‐light‐driven catalytic NADH oxidation. This enzyme‐coupled photoredox strategy sustains mitochondrial NADH/NAD+ imbalance, induces pyroptotic tumor cell death, suppresses tumor growth in vivo, and promotes systemic antitumor immunity ...
Yujin Kim   +10 more
wiley   +2 more sources

Flavin Catalysts in Organic Synthesis

open access: yesAngewandte Chemie, EarlyView.
Flavins and their congeners are potent catalysts for organic synthesis inspired by enzymatic transformations. In addition to catalysis in the flavin ground state via covalent intermediates, the excited singlet and triplet states unlock applications including photooxidation, photoreduction, and energy transfer via sensitization.
Jan Freudenberg, Golo Storch
wiley   +2 more sources

Home - About - Disclaimer - Privacy