Results 11 to 20 of about 85,015 (305)

Towards overcoming obstacles of type II photodynamic therapy: Endogenous production of light, photosensitizer, and oxygen

open access: yesActa Pharmaceutica Sinica B, 2023
Conventional photodynamic therapy (PDT) approaches face challenges including limited light penetration, low uptake of photosensitizers by tumors, and lack of oxygen in tumor microenvironments.
Lin Yu   +7 more
semanticscholar   +1 more source

A supramolecular photosensitizer derived from an Arene-Ru(II) complex self-assembly for NIR activated photodynamic and photothermal therapy

open access: yesNature Communications, 2022
Effective photosensitizers are of particular importance for the widespread clinical utilization of phototherapy. However, conventional photosensitizers are usually plagued by short-wavelength absorption, inadequate photostability, low reactive oxygen ...
Gang Xu   +7 more
semanticscholar   +1 more source

Rationally designed monoamine oxidase A‐activatable AIE molecular photosensitizer for the specific imaging and cellular therapy of tumors

open access: yesAggregate, 2022
Due to both the requirements of repeated complex organic synthesis and tedious biochemical verification experiments for the screening of new photosensitizers, the development of a satisfactory photosensitizer with excellent photosensitivity and highly ...
Yingcai Hu   +5 more
semanticscholar   +1 more source

A cell membrane-targeting AIE photosensitizer as a necroptosis inducer for boosting cancer theranostics

open access: yesChemical Science, 2022
The exploration of cellular organelle-specific anchoring photosensitizers with both prominent fluorescence imaging behavior and extraordinary reactive oxygen species (ROS) production capability is highly in demand but remains a severe challenge for ...
N. Niu   +7 more
semanticscholar   +1 more source

The photosensitizer-based therapies enhance the repairing of skin wounds

open access: yesFrontiers in Medicine, 2022
Wound repair remains a clinical challenge and bacterial infection is a common complication that may significantly delay healing. Therefore, proper and effective wound management is essential.
Xiaoying Ning   +4 more
doaj   +1 more source

Accessing Photoredox Transformations with an Iron(III) Photosensitizer and Green Light.

open access: yesJournal of the American Chemical Society, 2021
Efficient excited-state electron transfer between an iron(III) photosensitizer and organic electron donors was realized with green light irradiation.
Akin Aydogan   +10 more
semanticscholar   +1 more source

Photoinduced Endosomal Escape Mechanism: A View from Photochemical Internalization Mediated by CPP-Photosensitizer Conjugates

open access: yesMolecules, 2020
Endosomal escape in cell-penetrating peptide (CPP)-based drug/macromolecule delivery systems is frequently insufficient. The CPP-fused molecules tend to remain trapped inside endosomes and end up being degraded rather than delivered into the cytosol. One
Tet Htut Soe   +2 more
doaj   +1 more source

Photosensitizer Nanoparticles Boost Photodynamic Therapy for Pancreatic Cancer Treatment

open access: yesNano-Micro Letters, 2021
Current clinical studies of photodynamic therapy against pancreatic cancer are reviewed. Advantages of nanoparticles in boosting therapeutic efficacy of photodynamic therapy for pancreatic cancer treatment are summarized.
Huanyu Yang   +4 more
semanticscholar   +1 more source

PHOTODYNAMIC THERAPY: NEW LIGHT IN MEDICINE WORLD

open access: yesIndonesian Journal of Chemistry, 2010
Photodynamic therapy (PDT) is a considerably new kind of photochemotherapeutic treatment in medical field. It combines the use of three components, which are a photosensitizer, light and oxygen. Photosensitizer is a compound activated by light.
Venny Santosa, Leenawaty Limantara
doaj   +1 more source

Photodynamic action of the red laser on Propionibacterium acnes [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2017
: Background: Photodynamic therapy is a therapeutic modality that has consolidated its activity in the photooxidation of organic matter, which arises from the activity of reactive oxygen species.
Rogério Rodrigo Ramos   +5 more
doaj   +1 more source

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