Results 81 to 90 of about 46,741 (295)

Nanotechnology in photodynamic therapy

open access: yesOral Oncology Reports
Photodynamic therapy (PDT) is a minimally invasive treatment that employs a photosensitizer to destroy cancer cells. Its efficiency is determined by the activation light features, which include the photosensitizer molecule, light wavelength, tumour ...
Shrikant B. Mali   +2 more
doaj   +1 more source

Shaping Rolling Circle Amplification Products into DNA Nanoparticles by Incorporation of Modified Nucleotides and Their Application to In Vitro and In Vivo Delivery of a Photosensitizer

open access: yesMolecules, 2018
Rolling circle amplification (RCA) is a robust way to generate DNA constructs, which are promising materials for biomedical applications including drug delivery because of their high biocompatibility.
Kyoung-Ran Kim   +6 more
doaj   +1 more source

Wireless sequential dual light delivery for programmed PDT in vivo

open access: yesLight: Science & Applications
Using photodynamic therapy (PDT) to treat deep-seated cancers is limited due to inefficient delivery of photosensitizers and low tissue penetration of light. Polymeric nanocarriers are widely used for photosensitizer delivery, while the self-quenching of
Jiayi Liu   +7 more
doaj   +1 more source

Recent Approaches towards the Development of Ru(II) Polypyridyl Complexes for Anticancer Photodynamic Therapy

open access: yesCHIMIA, 2021
Photodynamic therapy (PDT) is a remarkable alternative or complementary technique to chemotherapy, radiotherapy or immunotherapy to treat certain forms of cancer.
Albert Gandioso   +2 more
doaj   +1 more source

Precisely Regulating 2.45 s Pure Blue Room‐Temperature Phosphorescence via Supramolecular Coordination

open access: yesAdvanced Science, EarlyView.
Herein, a pure deep blue room‐temperature phosphorescence (415 nm) with lifetime up to 2.45 s is successfully achieved by a covalently crosslinking purely organic material based on boric acid (BA) and 3,5‐dicarboxyphenylboronic acid (BOP) through a simple dehydration reaction, which can be adjusted precisely by supramolecular coordination with ...
Jun Wang   +5 more
wiley   +1 more source

Trifluoromethyl Boron Dipyrromethene Derivatives as Potential Photosensitizers for Photodynamic Therapy

open access: yesMolecules, 2018
In this study, two novel boron dipyrromethene-based photosensitizers (BDP3 and BDP6) substituted with three or six trifluoromethyl groups have been synthesized and characterized with various spectroscopic methods, and their photo-physical, photo-chemical,
Jian-Yong Liu   +3 more
doaj   +1 more source

Toward Singlet Oxygen Delivery at a Measured Rate: A Self-Reporting Photosensitizer

open access: yes, 2016
A Bodipy-based energy transfer cassette with a singlet oxygen reactive linker between the donor and acceptor modules has an interesting emergent property, if the acceptor module is also a photosensitizer.
Engin U. Akkaya (1789234)   +1 more
core   +1 more source

Carrier‐Free Stimulus‐Responsive Theranostic Nanoprodrug Enabling GSH‐Consumption‐Promoted Chemo‐Photodynamic Cancer Therapy

open access: yesAdvanced Science, EarlyView.
Leveraging the critical role of glutathione (GSH) in mediating drug resistance and scavenging reactive oxygen species (ROS) in cancer cells, a carrier‐free GSH‐consuming theranostic nanoprodrug, consisting of a BODIPY photosensitizer and the chemotherapeutic drug paclitaxel linked through a GSH‐consuming drug linker, is developed to deeply explore the ...
Hansheng Huang, Binglin Sui
wiley   +1 more source

A Self-Oxygenating Photosensitizer Enhances Photodynamic Antibacterial Therapy In Periodontitis

open access: yesInternational Dental Journal
Aim or purpose: There is reduced antibacterial efficacy in hypoxic microenvironments for existing photosensitizers exhibit. So, we designed a photosensitizer with catalytic oxygen-generation properties to enhance the therapeutic effect of antibacterial ...
Liu Yi, Shen Daonan, Ding Yi
doaj   +1 more source

Unlocking Long‐Lived Charge‐Separated State in Pentamethine Cyanine Based on Anionic Hofmeister Effect for Photodynamic Immunotherapy

open access: yesAdvanced Science, EarlyView.
Based on the anionic Hofmeister effect, a universal strategy of incorporation of stereo‐π anion BPh4− into a series of Cy5 skeletons to unlock long‐lived charge‐separated states was reported, wherein the weak electronic coupling and low charge recombination driving force hinder the charge recombination process, elevating the oxygen‐independent ROS ...
Xuan Zhao   +9 more
wiley   +1 more source

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