Results 101 to 110 of about 40,842 (301)

Hyperflav — perspective photosensitizer for PDT: cell studies

, 2010
Present studies investigated the effectiveness in vitro of Hyperflav application as a photosensitizer for photodynamic ...
Kholin, V.V., Yermak, P.V., Saienko, T.V., Gamaleia, N.F., Shalamay, A.S.   +4 more
core   +1 more source

Photocatalysis and Photodynamic Therapy in Diabetic Foot Ulcers (DFUs) Care: A Novel Approach to Infection Control and Tissue Regeneration

Molecules
Photocatalysis and photodynamic therapy have been increasingly used in the management of diabetic foot ulcers (DFUs), and their integration into increasingly innovative treatment protocols enables effective infection control.
Paweł Mikziński, Karolina Kraus, Rafał Seredyński, Jarosław Widelski, Emil Paluch   +4 more
doaj   +1 more source

Tyrosinase Driven‐Intracellular Polymerization of a Porphyrin Derivative Induced Immunogenic Death of Melanoma Cells and Strengthened Photodynamic Therapy

Advanced Science, EarlyView.
This study uses tyrosinase, which is highly expressed in melanoma, to drive porphyrins to polymerize and self‐assemble within tumor cells to form retented microstructures. This process induces immunogenic death and activates immune responses (M1 macrophages, dendritic cells, CD8+T cells), turning “cold” tumors into “hot” tumors.
Mian Tang, Junteng Qiu, Yunfeng Lu, Yahui Song, Xinyu Zhou, Tianshun Duan, Xuanqi Peng, Caixia Yin, Cheng Gao, Ruibing Wang   +9 more
wiley   +1 more source

FRET Quenching of Photosensitizer Singlet Oxygen Generation

, 2016
The development of activatable photodynamic therapy (PDT) has demonstrated a utility for effective photosensitizer quenchers. However, little is known quantitatively about Forster resonance energy transfer (FRET) quenching of photosensitizers, even ...
Mark T. Jarvi (2291113), Thomas T. Tidwell (1856539), Jonathan F. Lovell (527318), Yuanqin Liu (2277457), Annette D. Allen (2233894), Wei-Guo Cao (2387386), Gang Zheng (29050), Juan Chen (61123), Brian C. Wilson (706366)   +8 more
core   +1 more source

Overview of Potential Clinical Applications of Hemoglobin Vesicles (HbV) as Artificial Red Cells, Evidenced by Preclinical Studies of the Academic Research Consortium

Journal of Functional Biomaterials, 2017
Hemoglobin (Hb) is the most abundant protein in whole blood. This fact implies that the oxygen binding and releasing function of Hb is the most vital for sustaining life.
Hiromi Sakai
doaj   +1 more source

Dumbbell‐Structured Plasmonic‐Enhanced Optical Nanoprobes Boosting Photo‐Magnetic‐Acoustic Multimodal Imaging‐Guided Photodynamic‐Photothermal Synergistic Treatment and Immunogenic Death in Nasopharyngeal Carcinoma

Advanced Science, EarlyView.
This study reports a novel rationally‐designed optical nanoprobe based on dumbbell‐shaped mesoporous silica‐coated gold nanorods, loaded with rare‐earth oxides, photosensitizers, and tumor‐targeted peptides, enabling plasmonic‐enhanced multimodal imaging and PTT‐PDT synergy.
Baikang Zhuang, Yubiao Yang, Wen Han, Yi Tang, Chengxin Yao, Fuli Zhao, Wenxiao Fang, Jinjie Li, Xiaolan Huo, Yiqian An, Yuanzhi Shao, Botao Gao, Jinchang Yin   +12 more
wiley   +1 more source

Stability enhanced polyelectrolyte-coated gold nanorod-photosensitizer complexes for high/low power density photodynamic therapy

, 2014
Photodynamic therapy (PDT) is a promising treatment modality for cancer and other malignant diseases, however safety and efficacy improvements are required before it reaches its full potential and wider clinical use.
Chen, Xiaoyuan, Shi, Zhenzhi, Zhao, Xinmei, Wu, Aiguo, Ren, Wenzhi, Zou, Yuehong, Gong, An, Brown, Eric Michael Bratsolias   +7 more
core  

Combining Metal Nanoparticles with an Ir(III) Photosensitizer

We report on a new photocatalytic system that consists of an iridium-based photosensitizer that has been encapsulated into the pores of the metal–organic framework (MOF) MIL-101, which have then been loaded with metal nanoparticles. Loading with Ni leads
Martin Friedrich (11688613), Stephan Kümmel (1281717), Rhett Kempe (1510705), Mara Klarner (11688610), Birgit Weber (1727971), Gerald Hörner (2732863), Jürgen Senker (1682578), Thiago Branquinho de Queiroz (11688616), Sebastian Hammon (11688607)   +8 more
core   +1 more source

Self-Assembly of Mitochondria-Targeted Photosensitizer to Increase Photostability and Photodynamic Therapeutic Efficacy in Hypoxia

, 2020
The development of photosensitizers for cancer photodynamic therapy has been challenging due to their low photostability and therapeutic inefficacy in hypoxic tumor microenvironments.
Ryu, Ja-Hyoung, Jana, Batakrishna
core   +2 more sources

Self-assembled aldehyde dehydrogenase-activatable nano-prodrug for cancer stem cell-enriched tumor detection and treatment

Nature Communications
Cancer stem cells, characterized by high tumorigenicity and drug-resistance, are often responsible for tumor progression and metastasis. Aldehyde dehydrogenases, often overexpressed in cancer stem cells enriched tumors, present a potential target for ...
Bowen Li, Jianwu Tian, Fu Zhang, Chongzhi Wu, Zhiyao Li, Dandan Wang, Jiahao Zhuang, Siqin Chen, Wentao Song, Yufu Tang, Yuan Ping, Bin Liu   +11 more
doaj   +1 more source