Results 101 to 110 of about 44,938 (292)
Photosensitizer fluorescence emission during photodynamic therapy applied to dermatological diseases
, 2011 We present a first approach to predict the photosensitizer fluorescence dependence with depth during the Photodynamic Therapy applied to a skin disease commonly treated in the dermatological clinical practice.
F. Fanjul-Vélez +9 more
core +1 more source
Rewiring Pyroptosis to Potentiate Cancer Immunotherapy via a Gasdermin D Agonist Bypassing Caspase‐3
Advanced Science, EarlyView.This work introduces a small‐molecule agonist, DIBDO, that bypasses Casp‐3 to directly trigger GSDMD‐mediated pyroptosis in tumors. Activated by glutathione, DIBDO generates singlet oxygen and molecular iodine, blocking Casp‐3 pathways and inducing immunogenic cell death.
Dan Zhao +6 more
wiley +1 more source
Use of Cyclodextrins in Anticancer Photodynamic Therapy Treatment
Molecules, 2018 Photodynamic therapy (PDT) is mainly used to destroy cancerous cells; it combines the action of three components: a photoactivatable molecule or photosensitizer (PS), the light of an appropriate wavelength, and naturally occurring molecular oxygen. After
Amina Ben Mihoub +8 more
doaj +1 more source
Bodipy photosensitizer linked hybrid nanomaterials for photodynamic therapy [PDF]
, 2021 Photodynamic therapy (PDT) is an alternative clinically approved treatment method to obliterate the cancerous lesion by producing reactive oxygen species (ROS) via activated photosensitizer (PS) molecule at a certain wavelength1. In recent years, Bodipy (
Pehlivanoglu, Suray +3 more
core
Advanced Science, EarlyView.A supramolecular pyroptotic thermal switch encapsulates I3− within β‐cyclodextrin (β‐CD) and undergoes CaCO3 mineralization. Upon lysosomal acidification, CaCO3 is degraded, releasing Ca2+ and I3−. Concurrently, BODIPY activation converts I3− into I2, inducing oxidative stress and Ca2+ overload, which together trigger caspase‐3/GSDME‐mediated ...
Dan Wu +8 more
wiley +1 more source
Advanced Science, EarlyView.A viral luminogenic reporter with chemiluminescence/fluorescence dual‐response and efficient renal clearance was developed for non‐invasive imaging and urinalysis of H1N1 virus protease, allowing for remote detection of H1N1 virus infections and monitoring of antiviral therapeutic efficacy in living mice.
Bankang Ruan +9 more
wiley +1 more source
Hyperflav — perspective photosensitizer for PDT: cell studies
, 2010 Present studies investigated the effectiveness in vitro of Hyperflav application as a photosensitizer for photodynamic ...
Kholin, V.V. +4 more
core +1 more source
, 2018 Due to the rapid development of bacterial resistance, there is an urgent need to explore new antibacterial agents to substitute for traditional antibiotic therapy.
Yu Zhao (104852) +15 more
core +1 more source
Black Hole Quencher‐Enhanced Plasmonic Photothermal Conversion
Advanced Science, EarlyView.Researchers have developed a universal method to boost plasmonic photothermal conversion by attaching black hole quencher (BHQ) molecules to matched metal nanostructures. This hybrid approach increases efficiency by roughly threefold, reaching up to 69.1% in the near‐infrared‐II window.
Ruiyuan Zhang +3 more
wiley +1 more source
Enhanced cellular uptake of lactosomes using cell-penetrating peptides
Science and Technology of Advanced Materials, 2016 Polymeric micelles that are composed of synthetic polymers are generally size controllable and can be easily modified for various applications. Lactosomes (A3B-type) are biodegradable polymeric micelles composed of an amphipathic polymer, including three
Akiya Akahoshi +5 more
doaj +1 more source