Results 101 to 110 of about 30,561 (295)

Bidirectional Photoswitching of a Tailored Azobenzene with Red and Far‐Red Light Involving Triplet Sensitization in an Aqueous System

Advanced Science, EarlyView.
The action spectrum of a tailored azobenzene is shifted toward bio‐optical window through the chemical modification of its singlet and triplet energy levels. Consequently, the bidirectional photo‐switching of azobenzene in physiological conditions is achieved when excited by red and far‐red light, which offers greater tissue penetration.
Mila Miroshnichenko, Helen Hölzel, Edvinas Orentas, Karolis Kazlauskas, Pedro Ferreira, Fabienne Dumoulin, Carles Alcaide, Miquel Solà, Roger Bresolí‐Obach, Santi Nonell, Pankaj Bharmoria, Kasper Moth‐Poulsen   +11 more
wiley   +1 more source

Development of new photosensitizers for photodynamic therapy

, 2010
In the photo-dynamic therapy (PDT) uses it, that certain compounds, called photosensitizers, for cells only in the light toxicity. Thus, for example, tumor cells are killed in the organism targeted.
Ramaiah, Danaboyina, Epe, von Bernd
core   +1 more source

Global Trends and Research Progress of Photodynamic Therapy in Skin Cancer: A Bibliometric Analysis and Literature Review

Clinical, Cosmetic and Investigational Dermatology, 2023
Jiachen Sun,1,* Hongqing Zhao,1,* Lin Fu,2,* Jing Cui,3,* Yuguang Yang1 1Department of Dermatology, Fourth Medical Center of Chinese PLA General Hospital, Beijing, People’s Republic of China; 2Plastic Surgery Hospital, Chinese Academy of ...
Sun J, Zhao H, Fu L, Cui J, Yang Y
doaj  

Dual‐Mode Type I/II Photosensitization of a Stable Mesoporous Hydrogen‐Bonded Organic Framework for Antibacterial Therapy

Advanced Science, EarlyView.
A π‐conjugated donor–acceptor PDI monomer undergoes hydrogen‐bonded self‐assembly to form a robust mesoporous framework. The ordered molecular arrangement promotes efficient intersystem crossing and charge separation, leading to simultaneous Type I and Type II reactive oxygen species generation with a high singlet oxygen quantum yield.
Yi‐Lun Cheng, Hui Yuan, Yuhang Li, Zi‐Yu Wang, Rui Wang, Qi Yin, Xue‐Ning Ren, Miao Zheng, Yi Zeng, Tian‐Fu Liu, Zaisheng Ye   +10 more
wiley   +1 more source

Modulating the Charge Transfer Channels via Constructing Charge‐Assisted Hydrogen‐Bonded Organic Frameworks for Enhanced Photosynthesis of Hydrogen Peroxide

Advanced Science, EarlyView.
This work reports a strategy of engineering charge‐assisted hydrogen bonds to tailor charge transfer channels in HOFs, significantly improving their performance in photocatalytic H2O2 production. ABSTRACT The production of H2O2 via artificial photosynthesis is often limited by inefficient charge‐carrier separation, causing significant charge ...
Yajun Zhao, Xianzhi Lan, Tiantian Chen, Qijie Mo, Chao Peng, Jianbo Jia, Jiewei Liu, Cheng‐Yong Su   +7 more
wiley   +1 more source

Thionation Induces Efficient Generation of Excited Triplet State and Singlet Oxygen: Heavy Atom-Free BODIPY Photosensitizers Based on S1(n,π*) State

, 2020
The attachement of SR (R is alkyl or phenyl) makes BODIPY efficiently generate excited triplet state (T1) and singlet oxygen with quantum yield up to 0.82 (compared to 0.10 of parent BODIPY). This affords an efficient method to synthesize heavy atom free
Wenbin, Hu, XIan-Fu, Zhang, Mingyu, Liu
core   +1 more source

Heavy-Atom-Free Photosensitizers: From Molecular Design to Applications in the Photodynamic Therapy of Cancer

, 2021
ConspectusPhotodynamic therapy (PDT) is a clinically approved therapeutic modality that has shown great potential for the treatment of cancers owing to its excellent spatiotemporal selectivity and inherently noninvasive nature.
윤주영
core   +1 more source

Photodynamic Priming and Minocycline Overcome Chemoresistance by Reprogramming the Pancreatic Tumor Immune Microenvironment In Vivo

Advanced Science, EarlyView.
Dual priming with minocycline and photodynamic priming reprograms the pancreatic tumor microenvironment to overcome chemoresistance. By suppressing DNA repair enzyme Tdp1, inducing photooxidative damage, and enhancing irinotecan delivery via light‐activated nanoencapsulation, this strategy remodels the tumor microenvironment and drives immune ...
Fernanda V. Cabral, Jose Quilez‐Alburquerque, Olivia Mooradian, Shivendran Vytheswarran, Badri Parshad, Girgis Obaid, Huang‐Chiao Huang, Tayyaba Hasan   +7 more
wiley   +1 more source

Tyrosinase Driven‐Intracellular Polymerization of a Porphyrin Derivative Induced Immunogenic Death of Melanoma Cells and Strengthened Photodynamic Therapy

Advanced Science, EarlyView.
This study uses tyrosinase, which is highly expressed in melanoma, to drive porphyrins to polymerize and self‐assemble within tumor cells to form retented microstructures. This process induces immunogenic death and activates immune responses (M1 macrophages, dendritic cells, CD8+T cells), turning “cold” tumors into “hot” tumors.
Mian Tang, Junteng Qiu, Yunfeng Lu, Yahui Song, Xinyu Zhou, Tianshun Duan, Xuanqi Peng, Caixia Yin, Cheng Gao, Ruibing Wang   +9 more
wiley   +1 more source

Tungsten photosensitizers

, 2014
The development of photosensitizers is of great interest due to their ability to carry out difficult inorg. and org. reactions in their excited states. We have developed a new class of homoleptic arylisocyanide tungsten photosensitizers, W(CNAr)_6, and ...
Sattler, Wesley, Gray, Harry B., Winkler, Jay R.   +2 more
core