Results 121 to 130 of about 30,561 (295)

Photocatalyzed Dehalogenation Using Iron(III) Photosensitizers

, 2022
Due to its high abundance, low cost and low toxicity, photosensitizers based on iron have long been considered as the holy grail for photochemical applications. Unfortunately, with a few exceptions, these photosensitizers suffer from extremely short, sub-
Photo-IUPAC 2022, Troian-Gautier, Ludovic   +1 more
core  

H2S‐Amplified “Three‐in‐One” Antibacterial Strategy for Periodontitis Treatment Using a Photosensitive Pillararene‐Embedded COF/MOF Hybrid

Advanced Science, EarlyView.
The integration of ROS‐generating systems with H2S depletion strategies effectively overcomes the limitations imposed by endogenous antioxidant defenses on ROS‐based antimicrobial therapies. In this study, the Cu‐MOF is incorporated into pillararene‐embedded COF, achieving a “three‐in‐one” antimicrobial effect that markedly alleviated periodontal ...
Shuang Liang, Meng‐Hao Li, Liang Cheng, Tian‐Shou Zhang, Hui Hui, Yan Wang, Hong‐Pu Zhang, Bo‐Wen Liu, Lin Wang, Ying‐Wei Yang   +9 more
wiley   +1 more source

Chemistry Of Photofrin II And Some New Photosensitizers

, 1989
© 1989 SPIE. All rights reserved. The biological activity of a series of porphyrin dimers and trimers with ester and ether linkages, related to Photofrin II and some new photosensitizers with better optical properties are discussed.
Daniel F. Maichrzycki, Pandey, Ravindra K., Kevin M. Smith, Thomas J. Dougherty, Dougherty, Thomas J., Ravindra K. Pandey, Majchrzyckil, Daniel F., Smith, Kevin M.   +7 more
core   +1 more source

Supramolecular Assembly of Stepped‐Persistent ROS Nanogenerator for Sustained Tumor Immunotherapy

Advanced Science, EarlyView.
ROS catalytic systems often fail to achieve both effective tumor elimination and persistent immune activation due to their monotonous ROS production profiles. A stepped‐persistent ROS nanogenerator was developed by supramolecularly assembling multiple ROS generation modules within a nanofiber structure to simultaneously extend ROS generation duration ...
Zhenqiang Wang, Ming Qin, Wenjing Lai, Shiwen Chen, Fengling Wang, Dandan Xie, Maohua Chen, Changpeng Hu, Kui Wang, Rong Zhang, Guobing Li   +10 more
wiley   +1 more source

Senescent Cell Derived Artificial Vesicle‐Based Senolytic Sonovaccine Platform with Augmented Lymph Node Delivery and Antigen Cross‐Presentation Efficacy

Advanced Science, EarlyView.
A senolytic sonovaccine platform (SenoVac) is developed, in which senescent cell‐derived vesicles serve as broad senescent cell antigen reservior. The “2‐step” click chemistry strategy for effective lymph node delivery, and ultrasound‐triggered endosomal escape to boost cross‐presentation, ensures efficient senescent cell clearance and disease ...
Liang Zhang, Yubo Lai, Jia Wang, Lingling Liu, Jieyuan An, Mi Qu, Yuan Liang, Bijun Tan, Guodong Yang, Xuekang Yang, Lijun Yuan   +10 more
wiley   +1 more source

A Dye‐Sensitized Sensor for Oxygen Detection under Visible Light

Advanced Science
Sensors that can accurately assess oxygen (O2) concentrations in real time are crucial for a wide range of applications spanning personal health monitoring, environmental protection, and industrial process development.
Lionel Wettstein, Julia Specht, Vera Kesselring, Leif Sieben, Yanlin Pan, Daniel Käch, Dominika Baster, Frank Krumeich, Mario El Kazzi, Máté J. Bezdek   +9 more
doaj   +1 more source

Encapsulation of Porphyrinic Photosensitizers into Polymers monitored by NMR Spectroscopy

, 2016
Owing to several favorable properties such as phototoxicity combined with tumor accumulation and low dark toxicity, porphyrinic compounds have been playing an important role as photosensitizers in photodynamic therapy (PDT) for a long time. However, most
Vermathen, Martina, Furrer, Julien, Gjuroski, Ilche   +2 more
core  

Machine Learning‐Driven Prediction of Microplastic Aging Processes and Environmental Risk Assessment Across Multi‐Media Systems

Advanced Science, EarlyView.
This perspective proposes a cohesive machine learning strategy to decode microplastic aging. It advocates for Federated Learning to dismantle global data silos and introduces the TRACE framework (TRansport, Aging, Corona, Ecotoxicity). By integrating physics‐informed modeling with causal discovery, this approach bridges the laboratory‐field gap to ...
Yaping Lyu, Xinran Qiu, Xing Li, Tianhuan Yang, Xuetao Guo, Hao Qiu, Peng Zhang   +6 more
wiley   +1 more source

Inside‐Outside ROS Therapeutic Strategy Based on Piezoelectric Nano‐Urchin for Drug‐Resistant Bacteria Biofilm Infections

Advanced Science, EarlyView.
The contribution of this study lies not only in enabling effective treatment of drug‐resistant biofilm infections, but also in establishing a transferable therapeutic paradigm: Ultrasound‐triggered mechanical forces synergistically enhance piezoelectric polarization and nanozyme activity, driving functional ROS generation inside and outside biofilms ...
Xinjian Guo, Jin Yang, Mengjie An, Bingjie Lin, Tao Liu, Limin Zhang   +5 more
wiley   +1 more source

Cellular Uptake and Phototoxicity Optimization of Arene Ruthenium Porphyrin Derivatives

Inorganics
In this study, dinuclear and tetranuclear arene ruthenium porphyrins were synthesized and assessed for their potential as photosensitizers (PSs) in photodynamic therapy (PDT) using the Colo205 colon cancer cell line as a model system.
Zeinab Janbeih, Manuel Gallardo-Villagrán, Bruno Therrien, Mona Diab-Assaf, Bertrand Liagre, Ludmil Benov   +5 more
doaj   +1 more source