Design of Photosensitizing Agents for Targeted Antimicrobial Photodynamic Therapy [PDF]
Molecules, 2020 Photodynamic inactivation of microorganisms has gained substantial attention due to its unique mode of action, in which pathogens are unable to generate resistance, and due to the fact that it can be applied in a minimally invasive manner.
Maxime Klausen +2 more
doaj +11 more sources
Ιnclusion Complexes of Magnesium Phthalocyanine with Cyclodextrins as Potential Photosensitizing Agents [PDF]
Bioengineering, 2023 In this work, the preparation of inclusion complexes, (ICs) using magnesium phthalocyanine (MgPc) and various cyclodextrins (β-CD, γ-CD, HP-β-CD, Me-β-CD), using the kneading method is presented.
Eleni Kavetsou +5 more
doaj +7 more sources
A Skin Cancer Prophylaxis Study in Hairless Mice Using Methylene Blue, Riboflavin, and Methyl Aminolevulinate as Photosensitizing Agents in Photodynamic Therapy [PDF]
Pharmaceuticals, 2021 The high incidence of sunlight-induced human skin cancers reveals a need for more effective photosensitizing agents. In this study, we compared the efficacy of prophylactic photodynamic therapy (PDT) when methylene blue (MB), riboflavin (RF), or methyl ...
Hans Christian Wulf +4 more
doaj +5 more sources
Photosensitizing agents and the risk of non-melanoma skin cancer: a population-based case-control study. [PDF]
J Invest Dermatol, 2013 It is well-known that ultraviolet (UV) light exposure and a sun sensitive phenotype are risk factors for the development of non-melanoma skin cancer (NMSC), including basal cell carcinoma (BCC) and squamous cell carcinoma (SCC).
Robinson SN +5 more
europepmc +7 more sources
From non-covalent binding to irreversible DNA lesions: nile blue and nile red as photosensitizing agents. [PDF]
Sci Rep, 2016 We report a molecular modeling study, coupled with spectroscopy experiments, on the behavior of two well known organic dyes, nile blue and nile red, when interacting with B-DNA.
Gattuso H +4 more
europepmc +3 more sources
Identification of topical photosensitizing agents in humans.
Journal of Investigative Dermatology, 1978 A method is described for the detection of topical photosensitizers in humans. Test agents were applied to the untanned midback under an occlusive dressing for 6 hr and then exposed to broad-spectrum radiation containing UV-A and visible wavelengths from
K. Kaidbey, A. Kligman
semanticscholar +5 more sources
Amphiphilic Protoporphyrin IX Derivatives as New Photosensitizing Agents for the Improvement of Photodynamic Therapy [PDF]
Biomedicines, 2022 Photodynamic therapy (PDT) is a non-invasive therapeutic modality based on the interaction between a photosensitive molecule called photosensitizer (PS) and visible light irradiation in the presence of oxygen molecule.
Stéphane Desgranges +7 more
doaj +2 more sources
Carbohydrate–Porphyrin Conjugates with Two‐Photon Absorption Properties as Potential Photosensitizing Agents for Photodynamic Therapy [PDF]
, 2011 We report the synthesis of a series of conjugated zinc porphyrin oligomers designed as photodynamic therapy agents. These compounds exhibit exceptionally high two-photon absorption cross-sections, redshifted linear absorption spectra, and high singlet ...
Sylvain Achelle +4 more
semanticscholar +2 more sources
Drug Intake and Actinic Keratosis: A Case-Control Study [PDF]
Dermatology Practical & Conceptual, 2021 Background: Actinic keratosis (AK) is a form of premalignant keratinocyte dysplasia. Recently, the role of photosensitizing drugs in the development of AK has been postulated.
Andrea Sechi +5 more
doaj +3 more sources
A novel in vitro method for the detection and characterization of photosensitizers. [PDF]
PLoS ONE, 2010 Photoactivation and binding of photoactive chemicals to proteins is a known prerequisite for the formation of immunogenic photoantigens and the induction of photoallergy.
Nadine Karschuk +8 more
doaj +6 more sources