Results 101 to 110 of about 9,348 (281)

Flanking‐Group Engineering Unlocks Emerging Functionalities in Diketopyrrolopyrrole Semiconductors

Advanced Science, EarlyView.
This review presents a comprehensive and unified perspective of flanking‐group engineering in Diketopyrrolopyrrole (DPP) based organic semiconductors that connects molecular‐level design with cross‐device functionalities. By integrating insights from molecular design, solid‐state packing, and device physics, this review seeks to establish general ...
Xiaoyun Wu, Shanshan Zhou, Meng Li, Aung Ko Ko Kyaw, Xiao‐Lei Shi, Qian Liu   +5 more
wiley   +1 more source

A Multicenter Phase II Study on Photodynamic Therapy Using Talaporfin Sodium (ME2906) and a Semiconductor Laser (PNL6405CIN) for Intraepithelial Tumors of the Cervix

Reproductive Medicine and Biology
Purpose Conization for high‐grade cervical intraepithelial neoplasia (CIN2–3) often harms obstetric outcomes. Photodynamic therapy (PDT) with talaporfin sodium provides a cervix‐sparing alternative with short photosensitivity.
Hirotake Murakami, Masaru Sakamoto, Hisamori Kato, Kiyohiko Miyake, Kenji Umayahara, Toshiya Itoh, Madoka Matsuya, Toshiaki Shibata, Toshiyuki Uchida, Masakazu Abe, Tomomi Kotani, Hiroaki Itoh, Naohiro Kanayama   +12 more
doaj   +1 more source

Medications and cutaneous reactions to sunlight: analysis of photosensitizing agents [PDF]

Introducere Reacțiile adverse cutanate la expunerea solară reprezintă un aspect important al efectelor secundare ale medicamentelor. Aproximativ 10% din populație poate experimenta astfel de reacții, iar pacienții spitalizați prezintă un risc crescut.
Mihalachi-Anghel, Maria, Pogonea, Ina, Chiriac, Tatiana, Latus, Svetlana   +3 more
core  

Dual‐Functional Silent‐Region SERS Nanoplatform for Real‐Time Bacterial Tracking and Wound Healing Therapy

Advanced Science, EarlyView.
ABSTRACT Bacterial wound infections, particularly those caused by Escherichia coli and Pseudomonas aeruginosa, are difficult to treat due to biofilm formation, multidrug resistance, and chronic inflammation. Here, we report a multifunctional nanoplatform based on a surface‐enhanced Raman scattering (SERS) probe that enables simultaneous photodynamic ...
Hanbin Deng, Rui Wang, Dianqi Zhang, Wei Zhang, Jaebum Choo, Fabiao Yu, Shaowen Cheng   +6 more
wiley   +1 more source

Indocyanine green-activated photodynamic therapy with diode laser eradicates Enterococcus faecalis in infected root canals: An in vitro study

Dental Research Journal
Background: The current endodontic disinfection techniques may be supplemented with photodynamic therapy (PDT), which is believed to eliminate intracanal bacteria more efficiently.
Ali Falah Rfysh, Mohammed Rahid Hameed, Saeed Asgary, Mustafa Shubbar   +3 more
doaj   +1 more source

Rewiring Pyroptosis to Potentiate Cancer Immunotherapy via a Gasdermin D Agonist Bypassing Caspase‐3

Advanced Science, EarlyView.
This work introduces a small‐molecule agonist, DIBDO, that bypasses Casp‐3 to directly trigger GSDMD‐mediated pyroptosis in tumors. Activated by glutathione, DIBDO generates singlet oxygen and molecular iodine, blocking Casp‐3 pathways and inducing immunogenic cell death.
Dan Zhao, Lingling Zhang, Yue Wen, Lianghui Cheng, Sidan Tian, Fanling Meng, Liang Luo   +6 more
wiley   +1 more source

A Supramolecular Thermal Switch for Precision Pyroptosis via Host−Guest Recognition and Electrostatic Interactions

Advanced Science, EarlyView.
A supramolecular pyroptotic thermal switch encapsulates I3− within β‐cyclodextrin (β‐CD) and undergoes CaCO3 mineralization. Upon lysosomal acidification, CaCO3 is degraded, releasing Ca2+ and I3−. Concurrently, BODIPY activation converts I3− into I2, inducing oxidative stress and Ca2+ overload, which together trigger caspase‐3/GSDME‐mediated ...
Dan Wu, Jie Zhou, Yibin Cao, Kunmin Ping, Borui Zhao, Yanrong Yang, Chunyang Yu, Xinyang Yu, Shaolong Qi   +8 more
wiley   +1 more source

Molecular Engineering Boosts Photon‐Activated Immunotherapy for Prostate Cancer Through Concurrent Pyroptosis and cGAS‐STING Pathway Activation

Angewandte Chemie, EarlyView.
The engineered DTSe‐based photosensitizer, DZTSe, emerges as an avant‐garde molecular entity, which can distribute to both the endoplasmic reticulum and mitochondria to concurrently trigger pyroptosis and activate the cGAS‐STING pathway. This dual‐action strategy effectively reprograms the tumor microenvironment, enabling potent eradication of primary ...
Cheng Zhang, Xiaolan Yin, Jeongyeon Hong, Qixian Chen, Weijie Chi, Jingyun Wang, Juyoung Yoon, Haidong Li   +7 more
wiley   +2 more sources

Photodynamic Therapy: Occupational Hazards and Preventative Recommendations for Clinical Administration by Healthcare Providers [PDF]

, 2016
Objective: Photodynamic therapy (PDT) as a medical treatment for cancers is an increasing practice in clinical settings, as new photosensitizing chemicals and light source technologies are developed and applied.
James A. Radosevich (2243890), Steven E. Lacey (7931000), William A. Paradise (7931003), Michael D. Colvard (7931006), John D. Breskey (7930997), Benjamin J. Vesper (2243887)   +5 more
core  

Renal Clearable Luminogenic Reporter for Ultrasensitive Influenza Virus Imaging and Efficient Antiviral Therapies Monitoring in Living Mice

Advanced Science, EarlyView.
A viral luminogenic reporter with chemiluminescence/fluorescence dual‐response and efficient renal clearance was developed for non‐invasive imaging and urinalysis of H1N1 virus protease, allowing for remote detection of H1N1 virus infections and monitoring of antiviral therapeutic efficacy in living mice.
Bankang Ruan, Chudan Liang, Meilin Hu, Weiping Xu, Jingjing Che, Jun Qian, Bingcai Jiang, Linna Liu, Xiancai Ma, Jiaguo Huang   +9 more
wiley   +1 more source