Results 81 to 90 of about 1,507,381 (281)

Combined effects of thermal neutrons, gamma rays, red band light and neutron capture agents to the morphological indicators of cells line L929 in vitro

Ядерна фізика та енергетика, 2016
ombined effect of neutron, gamma and light (red band) irradiation to morphological changes in the cell culture was investigated. It was found that in the presence of photosensitizing agents with neutron capture properties with molecular structure and ...
H. Yo. Lavrenchuk, Yu. B. Shevchenko, V. V. Tryshyn, V. A. Libman, I. V. Kozlovska, D. D. Gapeenko, Ya. V. Pshenychnyi, V. M. Venedyktov, Yu. S. Ivanov   +8 more
doaj  

ANTIMICROBIAL ACTIVITY AND CHEMICAL COMPOSITION OF TWO EXPERIMENTAL GELS BASED ON ESSENTIAL OILS

Studia Universitatis Babes-Bolyai Chemia, 2020
In this study, the comparative testing of the antimicrobial efficacy of 2 experimental photosensitizers (PS-H; PS-T) based on natural compounds with a commercial one based on toluidine blue O (TBO) FotoSan® was performed, by antimicrobial tests with G ...
Laura Monica DASCALU (RUSU), Marioara MOLDOVAN, Doina PRODAN, Irina CIOTLAUS, Rahela CARPA, Razvan ENE, Sorina SAVA, Radu CHIFOR, Mindra Eugenia BADEA   +8 more
doaj   +1 more source

Photosensitizing Nanoparticles and The Modulation of Reactive Oxygen Species generation [PDF]

, 2015
The association of PhotoSensitizer (PS) molecules with nanoparticles (NPs) forming photosensitizing NPs, has emerged as a therapeutic strategy to improve PS tumor targeting, to protect PS from deactivation reactions and to enhance both PS solubility and ...
Dayane Batista Tada, Mauricio S. Baptista, Dayane B. Tada, Mauricio da Silva Baptista   +3 more
core   +1 more source

Rewiring Pyroptosis to Potentiate Cancer Immunotherapy via a Gasdermin D Agonist Bypassing Caspase‐3

Advanced Science, EarlyView.
This work introduces a small‐molecule agonist, DIBDO, that bypasses Casp‐3 to directly trigger GSDMD‐mediated pyroptosis in tumors. Activated by glutathione, DIBDO generates singlet oxygen and molecular iodine, blocking Casp‐3 pathways and inducing immunogenic cell death.
Dan Zhao, Lingling Zhang, Yue Wen, Lianghui Cheng, Sidan Tian, Fanling Meng, Liang Luo   +6 more
wiley   +1 more source

Investigation into Novel Mitochondrial Targeting Cyanine Dyes as Potential Photosensitizing Agents for Photodynamic Therapy [PDF]

Carbocyanine dyes are a class of organic compounds with high conjugation that enable them to act as photosensitizing agents in photodynamic therapy (PDT).
Brewer, David
core   +1 more source

A Supramolecular Thermal Switch for Precision Pyroptosis via Host−Guest Recognition and Electrostatic Interactions

Advanced Science, EarlyView.
A supramolecular pyroptotic thermal switch encapsulates I3− within β‐cyclodextrin (β‐CD) and undergoes CaCO3 mineralization. Upon lysosomal acidification, CaCO3 is degraded, releasing Ca2+ and I3−. Concurrently, BODIPY activation converts I3− into I2, inducing oxidative stress and Ca2+ overload, which together trigger caspase‐3/GSDME‐mediated ...
Dan Wu, Jie Zhou, Yibin Cao, Kunmin Ping, Borui Zhao, Yanrong Yang, Chunyang Yu, Xinyang Yu, Shaolong Qi   +8 more
wiley   +1 more source

ADME potential of porphyrin derivative from petroleum [PDF]

BIO Web of Conferences
Chlorins are tetrapyrrole pigments that are formally described as partially hydrogenated porphyrins, specifically dihydroporphyrins. This structural difference gives them distinct chemical and photophysical properties that are essential for their ...
Koleva Yana, Trifonova Viktoria, Kolev Asen, Tasheva Yordanka   +3 more
doaj   +1 more source

Renal Clearable Luminogenic Reporter for Ultrasensitive Influenza Virus Imaging and Efficient Antiviral Therapies Monitoring in Living Mice

Advanced Science, EarlyView.
A viral luminogenic reporter with chemiluminescence/fluorescence dual‐response and efficient renal clearance was developed for non‐invasive imaging and urinalysis of H1N1 virus protease, allowing for remote detection of H1N1 virus infections and monitoring of antiviral therapeutic efficacy in living mice.
Bankang Ruan, Chudan Liang, Meilin Hu, Weiping Xu, Jingjing Che, Jun Qian, Bingcai Jiang, Linna Liu, Xiancai Ma, Jiaguo Huang   +9 more
wiley   +1 more source

Black Hole Quencher‐Enhanced Plasmonic Photothermal Conversion

Advanced Science, EarlyView.
Researchers have developed a universal method to boost plasmonic photothermal conversion by attaching black hole quencher (BHQ) molecules to matched metal nanostructures. This hybrid approach increases efficiency by roughly threefold, reaching up to 69.1% in the near‐infrared‐II window.
Ruiyuan Zhang, Xinru Chen, Lin Shen, Jin Li   +3 more
wiley   +1 more source

Engineering a 660 nm‐Responsive Optogenetic Inducer of Pyroptosis for Precision Cancer Therapy

Advanced Science, EarlyView.
This study reports a bioorthogonal pyroptosis inducer, PyroRACS. By using a red‐light‐responsive Cre‐On genetic switch to control the expression of highly cytotoxic GSDMDNT, PyroRACS enables the artificial induction of pyroptosis with precise spatiotemporal control.
Mengkai Zhang, Zhichao Li, Yonghao Ma, Yangyang Sun, Wei Chen, Weiren Huang   +5 more
wiley   +1 more source