Results 61 to 70 of about 9,348 (281)

Photosensitizers-Loaded Nanocarriers for Enhancement of Photodynamic Therapy in Melanoma Treatment

Pharmaceutics, 2023
Malignant melanoma poses a significant global health burden. It is the most aggressive and lethal form of skin cancer, attributed to various risk factors such as UV radiation exposure, genetic modifications, chemical carcinogens, immunosuppression, and ...
Ana Maria Udrea, Adriana Smarandache, Andra Dinache, Catalina Mares, Simona Nistorescu, Speranta Avram, Angela Staicu   +6 more
doaj   +1 more source

Negotiating in a Foreign Land: Understanding the Curious Interactions Between Intracellular Mitochondria and Internalized Nanoparticles

Advanced Materials Interfaces, EarlyView.
Therapeutic nano‐drug delivery systems interact with cellular mitochondria in a multitude of ways. While the complexity of such interactions disrupts the mitochondrial electron transport chain and increases reactive oxygen species production, thereby contributing to nanoparticle toxicity, they also present unique theranostic opportunities in diseases ...
Sourav Bhattacharjee
wiley   +1 more source

Photodynamic inactivation of in vitro bacterial cultures from pressure ulcers Inativação fotodinâmica de culturas de bactérias in vitro provenientes de úlceras de pressão

Acta Cirúrgica Brasileira, 2006
PURPOSE: To evaluate in vitro the antibacterial effect of diode laser light of wavelength 650 nm, in association with the photosensitive substance toluidine blue, on the bacteria in infected skin ulcers.
Paulo de Tarso Camillo de Carvalho, Ana Paula da Costa Marques, Felipe Abdalla dos Reis, Ana Carulina Guimarães Belchior, Iandara Schettert Silva, Carlos Alexandre Habitante, Daniela Aparecida Sussai   +6 more
doaj   +1 more source

Photodynamic Inactivation of Bacteria and Biofilms with Benzoselenadiazole-Doped Metal-Organic Frameworks

Molecules, 2022
Bacterial biofilms are difficult to treat due to their resistance to traditional antibiotics. Although photodynamic therapy (PDT) has made significant progress in biomedical applications, most photosensitizers have poor water solubility and can thus ...
Liang Luan, Lehan Du, Wenjun Shi, Yunhui Li, Quan Zhang   +4 more
doaj   +1 more source

Gold-riboflavin hybrid nanostrucutures as possible photodynamic therapy agents [PDF]

, 2023
This study reports on the optical properties of hybrid nanostructures that comprise gold nanoparticles (Au NPs) and biomolecule riboflavin (vitamin B2, Rb).
Tošić, Dragana, Pajović, Jelena, Đoković, Vladimir, Božanić, Dušan, Dojčilović, Radovan   +4 more
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SNAP-tag technology mediates site specific conjugation of antibody fragments with a photosensitizer and improves target specific phototoxicity in tumor cells [PDF]

, 2022
S.2487-2495Cancer cells can be killed by photosensitizing agents that induce toxic effects when exposed to nonhazardous light, but this also causes significant damage to surrounding healthy cells.
Kampmeier, F., Merk, H.F., Hussain, A.F., Tur, M.K., Barth, S., Felbert, V. von   +5 more
core   +1 more source

Extrusion Bioprinting for Wound Healing: Innovations in Functionalized Bioinks and Bioprinting Technology

Advanced Materials Technologies, EarlyView.
Extrusion‐based bioprinting (EBB) has emerged as a versatile biofabrication platform capable of precisely depositing bioinks composed of biomaterials, cells, and bioactive agents to generate patient‐specific, biomimetic skin constructs. This paper presents a state‐of‐the‐art and forward‐looking overview of EBB for wound healing, encompassing printing ...
Hien‐Phuong Le, Anh Tuan Trong Tran, Ammara Waheed, Tran Thanh Tung, Dusan Losic   +4 more
wiley   +1 more source

Effect of antibacterial photodynamic therapy with chitosan nanoparticles on Aggregatibacter actinomycetemcomitans

Photodiagnosis and Photodynamic Therapy
Background: This study aimed to assess the effect of antibacterial photodynamic therapy (aPDT) with chitosan nanoparticles on Aggregatibacter actinomycetemcomitans (A. actinomycetemcomitans) in the culture medium. Materials and Methods: In this in vitro,
Amir Mohammad Kamalou, Ferena Sayar, Babak Iranpour   +2 more
doaj   +1 more source

Genome‐Wide CRISPR Screen Identifies a microRNA Orchestrating Pleiotropic Resistance to Targeted Therapy and T Cell Immunity in Melanoma

Advanced Science, EarlyView.
A genome‐wide microRNA CRISPR screen identifies miR‐18a as a master regulator of cross‐resistance in melanoma. Loss of miR‐18a activates the AJUBA–YAP/Hippo axis to confer BRAFi resistance and enhances THBS1–CD47 interaction to impair CD8+ T cell immunity. hnRNP A1 is identified as an upstream regulator of miR‐18a processing.
Zhao Wang, Haotian Liu, Xueqi Wang, Jianjin Teng, Zihan Zheng, Jingya Zhang, Wanyi Xiao, Qian Liang, Jiaxin Li, Xiaomeng Jia, Xin Feng, Hongzhang Cui, Menghan Luo, Tielong Yang, Liuxing Wu, Ke Zhao, Weilong Yang, Mulin Jun Li, Dandan Huang, Jilong Yang   +19 more
wiley   +1 more source

Combined exposure to natural UV radiation and irritant, sensitizing and photosensitizing substances [PDF]

, 2010
Celem pracy badawczej była ocena narażenia zawodowego pracowników na łączne oddziaływanie naturalnego promieniowania UV i czynników chemicznych. Reprezentatywną grupą pracowników narażonych na łączne oddziaływanie szkodliwych dla zdrowia czynników była ...
Pośniak, M., Wolska, A., Szewczyńska, M., Głogowski, P.   +3 more
core